Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DP111_RS00810 Genome accession   NZ_CP030124
Coordinates   126084..127034 (+) Length   316 a.a.
NCBI ID   WP_014637312.1    Uniprot ID   -
Organism   Streptococcus suis strain SH1510     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 121084..132034
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP111_RS00800 (DP111_00800) - 124648..125013 (+) 366 WP_002936568.1 DUF1033 family protein -
  DP111_RS00805 (DP111_00805) - 125048..125998 (-) 951 WP_024394700.1 S66 peptidase family protein -
  DP111_RS00810 (DP111_00810) comYA 126084..127034 (+) 951 WP_014637312.1 competence type IV pilus ATPase ComGA Machinery gene
  DP111_RS00815 (DP111_00815) comYB 126946..127983 (+) 1038 WP_043032925.1 competence type IV pilus assembly protein ComGB Machinery gene
  DP111_RS00820 (DP111_00820) comYC 127985..128266 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  DP111_RS00825 (DP111_00825) comGD 128247..128654 (+) 408 WP_024394702.1 competence type IV pilus minor pilin ComGD -
  DP111_RS00830 (DP111_00830) comYE 128626..128919 (+) 294 WP_024394703.1 competence type IV pilus minor pilin ComGE Machinery gene
  DP111_RS00835 (DP111_00835) comGF/cglF 128906..129340 (+) 435 WP_029750050.1 competence type IV pilus minor pilin ComGF Machinery gene
  DP111_RS00840 (DP111_00840) comGG 129318..129728 (+) 411 WP_024394705.1 competence type IV pilus minor pilin ComGG -
  DP111_RS00845 (DP111_00845) comYH 129785..130738 (+) 954 WP_024394706.1 class I SAM-dependent methyltransferase Machinery gene
  DP111_RS00850 (DP111_00850) - 130788..131975 (+) 1188 WP_014637319.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35477.26 Da        Isoelectric Point: 5.2978

>NTDB_id=299412 DP111_RS00810 WP_014637312.1 126084..127034(+) (comYA) [Streptococcus suis strain SH1510]
MIQEKARKLIEEAVADRVSDIYLVPRGQDYQVYHRIMDEREFVQDLAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNEQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=299412 DP111_RS00810 WP_014637312.1 126084..127034(+) (comYA) [Streptococcus suis strain SH1510]
ATGATTCAAGAAAAAGCAAGAAAGTTGATTGAAGAGGCGGTGGCGGATAGGGTCAGTGACATTTATCTGGTTCCTCGTGG
TCAGGACTACCAAGTCTACCATCGCATCATGGATGAACGGGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGATTAAATGTTGGTGAAAAACGCCGTAGTCAGCAGGGTTCCTGTGATTATGAT
TATGGCAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGAGATTATCGTGGTAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTTAAGTTCTGGTTTGAGGCGGCCGAGCGACTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACGCTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACTATCGAGGATCCTGTCGAGATCAAGCAGGAGGATATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTGATCAAACTGTCCCTCCGCCATCGGCCAGACTTGCTCATCATCGGTGAAATTCGGGATGCGGAAACGG
CGCGGGCGGTCATCAGGGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGCCCTGAAGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGCTTGATTGG
GGGAGGAGGTGTAGTGGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGAACAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.595

98.418

0.646
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.595

98.418

0.646
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

65.484

98.101

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.952

98.418

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

53.943

100

0.541
  comGA Latilactobacillus sakei subsp. sakei 23K

41.516

87.658

0.364

Multiple sequence alignment