Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   DP111_RS00845 Genome accession   NZ_CP030124
Coordinates   129785..130738 (+) Length   317 a.a.
NCBI ID   WP_024394706.1    Uniprot ID   A0A0Z8SW51
Organism   Streptococcus suis strain SH1510     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 124785..135738
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DP111_RS00805 (DP111_00805) - 125048..125998 (-) 951 WP_024394700.1 S66 peptidase family protein -
  DP111_RS00810 (DP111_00810) comYA 126084..127034 (+) 951 WP_014637312.1 competence type IV pilus ATPase ComGA Machinery gene
  DP111_RS00815 (DP111_00815) comYB 126946..127983 (+) 1038 WP_043032925.1 competence type IV pilus assembly protein ComGB Machinery gene
  DP111_RS00820 (DP111_00820) comYC 127985..128266 (+) 282 WP_011921720.1 competence type IV pilus major pilin ComGC Machinery gene
  DP111_RS00825 (DP111_00825) comGD 128247..128654 (+) 408 WP_024394702.1 competence type IV pilus minor pilin ComGD -
  DP111_RS00830 (DP111_00830) comYE 128626..128919 (+) 294 WP_024394703.1 competence type IV pilus minor pilin ComGE Machinery gene
  DP111_RS00835 (DP111_00835) comGF/cglF 128906..129340 (+) 435 WP_029750050.1 competence type IV pilus minor pilin ComGF Machinery gene
  DP111_RS00840 (DP111_00840) comGG 129318..129728 (+) 411 WP_024394705.1 competence type IV pilus minor pilin ComGG -
  DP111_RS00845 (DP111_00845) comYH 129785..130738 (+) 954 WP_024394706.1 class I SAM-dependent methyltransferase Machinery gene
  DP111_RS00850 (DP111_00850) - 130788..131975 (+) 1188 WP_014637319.1 acetate kinase -
  DP111_RS00855 (DP111_00855) - 132290..132841 (+) 552 WP_014636756.1 folate family ECF transporter S component -
  DP111_RS00860 (DP111_00860) - 132895..134151 (+) 1257 WP_024394707.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  DP111_RS00865 (DP111_00865) pepA 134196..135257 (-) 1062 WP_024394708.1 glutamyl aminopeptidase -
  DP111_RS00870 (DP111_00870) - 135404..135688 (+) 285 WP_012774909.1 DUF4651 domain-containing protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35744.84 Da        Isoelectric Point: 4.5053

>NTDB_id=299417 DP111_RS00845 WP_024394706.1 129785..130738(+) (comYH) [Streptococcus suis strain SH1510]
MNFEKIEQAYDLLLENVQTIQNQLGTNIYDAMIEQNAAYVANQHETDLVVNNNKTLKQLDLTKEEWRRAYQFLLIKANQT
EPMQYNHQFTPDSIGFILSFLVDQLVPTQKVTVLEIGSGTGNLAQTILNASQKELDYLGIEVDDLLIDLSASIADVMQAD
ISFAQGDAVRPQILKESQVILGDLPIGYYPDDQIASRYQVASPNEHTYAHHLLMEQSLKYLEKNGFAILLAPNDLLTSPQ
SDLLKGWLQEQANIVAMIALPPNLFGKAAMAKSIFVLQKKAARSLTPFVYPLQSLQEPEAIQKFMLNFKNWKQENAI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=299417 DP111_RS00845 WP_024394706.1 129785..130738(+) (comYH) [Streptococcus suis strain SH1510]
ATGAATTTTGAAAAGATCGAACAGGCTTACGACCTGCTATTAGAAAACGTACAGACTATCCAAAACCAGCTAGGTACCAA
TATCTATGATGCCATGATTGAGCAAAATGCTGCTTACGTAGCTAATCAGCATGAGACGGACCTTGTTGTCAATAATAACA
AGACCTTGAAACAACTAGATTTAACCAAGGAAGAATGGCGTCGTGCCTATCAATTCTTGCTCATCAAGGCCAATCAGACT
GAACCCATGCAGTATAATCACCAGTTCACACCAGACTCTATCGGATTTATCCTATCTTTTCTAGTAGACCAATTGGTGCC
GACTCAAAAGGTGACGGTTCTGGAAATTGGTTCGGGGACAGGCAATCTAGCTCAGACCATTCTCAACGCCAGCCAGAAAG
AATTGGATTACTTGGGGATCGAAGTGGACGACCTCTTGATTGATTTGTCGGCAAGTATTGCGGATGTCATGCAGGCAGAT
ATTTCTTTTGCTCAGGGAGATGCGGTACGTCCGCAGATTTTGAAGGAAAGTCAAGTAATTTTGGGAGATTTGCCTATTGG
CTACTATCCAGATGACCAGATTGCTAGCCGCTATCAGGTCGCCAGCCCAAATGAACATACCTACGCCCATCATTTACTCA
TGGAACAATCCCTCAAATATCTGGAAAAAAATGGTTTTGCGATTTTGTTGGCTCCAAATGATTTATTGACTAGTCCGCAA
AGCGATTTGCTGAAAGGTTGGTTACAGGAGCAAGCCAATATTGTTGCCATGATTGCCCTACCACCAAATCTCTTTGGGAA
GGCTGCTATGGCCAAGTCTATTTTTGTCTTGCAAAAGAAAGCTGCAAGATCATTGACGCCGTTTGTTTATCCCTTACAAA
GTCTTCAAGAACCAGAAGCTATTCAGAAGTTCATGCTCAATTTCAAAAATTGGAAGCAAGAGAATGCAATTTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-283)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8SW51

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

60.759

99.685

0.606
  comYH Streptococcus mutans UA159

60.443

99.685

0.603

Multiple sequence alignment