Detailed information NTG0298388

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: DK875_RS10030
• Genome accession: NZ_CP030020
• Coordinates: 2040404..2040685 (-)
• Length: 93 a.a.
• NCBI ID: WP_002936550.1
• Uniprot ID: G7SD61
• Organism: Streptococcus suis strain ISU2514
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2035404..2045685

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK875_RS09995 (DK875_10400)	-	2035816..2036367 (-)	552	WP_014636756.1	folate family ECF transporter S component	-
DK875_RS10000 (DK875_10410)	-	2036682..2037869 (-)	1188	WP_002936543.1	acetate kinase	-
DK875_RS10005 (DK875_10415)	comYH	2037919..2038872 (-)	954	WP_002936545.1	class I SAM-dependent methyltransferase	Machinery gene
DK875_RS10010 (DK875_10420)	comGG	2038929..2039339 (-)	411	WP_002936546.1	competence type IV pilus minor pilin ComGG	-
DK875_RS10015 (DK875_10425)	comGF/cglF	2039317..2039751 (-)	435	WP_002936547.1	competence type IV pilus minor pilin ComGF	Machinery gene
DK875_RS10020 (DK875_10430)	comYE	2039738..2040031 (-)	294	WP_002936548.1	competence type IV pilus minor pilin ComGE	Machinery gene
DK875_RS10025 (DK875_10435)	comGD	2040115..2040423 (-)	309	WP_002936549.1	competence type IV pilus minor pilin ComGD	-
DK875_RS10030 (DK875_10440)	comYC	2040404..2040685 (-)	282	WP_002936550.1	competence type IV pilus major pilin ComGC	Machinery gene
DK875_RS10035 (DK875_10445)	comYB	2040687..2041559 (-)	873	WP_053866392.1	type II secretion system F family protein	Machinery gene
DK875_RS10040 (DK875_10450)	comYA	2041471..2042421 (-)	951	WP_002936562.1	competence type IV pilus ATPase ComGA	Machinery gene
DK875_RS10045 (DK875_10455)	-	2042507..2043457 (+)	951	WP_002936565.1	S66 peptidase family protein	-
DK875_RS10050 (DK875_10460)	-	2043492..2043857 (-)	366	WP_002936568.1	DUF1033 family protein	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10452.31 Da
• Isoelectric Point: 5.1667

>NTDB_id=298388 DK875_RS10030 WP_002936550.1 2040404..2040685(-) (comYC) [Streptococcus suis strain ISU2514]
MKKLVEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSKQKDAVQEKGNAAVVKVVESQMELYELEHDEEATVEDLQQAGYI
TEKQAKQYATAKK

Nucleotide

• Length: 282 bp

>NTDB_id=298388 DK875_RS10030 WP_002936550.1 2040404..2040685(-) (comYC) [Streptococcus suis strain ISU2514]
ATGAAAAAATTAGTTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTCGTTTTGGGGATCATTAGCCTGCT
CTTGCTCTTATTTGTGCCAAATTTGAGCAAACAAAAGGATGCTGTTCAAGAGAAAGGAAATGCTGCCGTTGTCAAAGTAG
TGGAGAGTCAGATGGAGCTCTACGAATTGGAACATGACGAGGAAGCAACGGTGGAGGATTTGCAACAGGCAGGTTATATT
ACTGAAAAACAAGCAAAACAGTATGCTACGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: G7SD61

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	92.473	100	0.925
comGC/cglC	Streptococcus pneumoniae TIGR4	68.182	94.624	0.645
comGC/cglC	Streptococcus pneumoniae Rx1	68.182	94.624	0.645
comGC/cglC	Streptococcus pneumoniae D39	68.182	94.624	0.645
comGC/cglC	Streptococcus pneumoniae R6	68.182	94.624	0.645
comGC/cglC	Streptococcus mitis SK321	69.412	91.398	0.634
comGC/cglC	Streptococcus mitis NCTC 12261	69.412	91.398	0.634
comYC	Streptococcus gordonii str. Challis substr. CH1	65.169	95.699	0.624
comYC	Streptococcus mutans UA140	61.364	94.624	0.581
comYC	Streptococcus mutans UA159	61.364	94.624	0.581
comGC	Lactococcus lactis subsp. cremoris KW2	59.091	94.624	0.559
comGC	Staphylococcus aureus MW2	50	83.871	0.419
comGC	Staphylococcus aureus N315	50	83.871	0.419
comGC	Bacillus subtilis subsp. subtilis str. 168	46.667	80.645	0.376