Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   CSB78_RS04650 Genome accession   NZ_CP029671
Coordinates   904356..904925 (-) Length   189 a.a.
NCBI ID   WP_000872882.1    Uniprot ID   A0A7U7EXA1
Organism   Staphylococcus aureus strain AR_0222     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 899356..909925
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CSB78_RS04605 (CSB78_0818) - 899833..900441 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  CSB78_RS04610 (CSB78_0819) rplL 900616..900984 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  CSB78_RS04615 (CSB78_0820) rplJ 901027..901527 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  CSB78_RS04625 (CSB78_0821) rplA 901799..902491 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  CSB78_RS04630 (CSB78_0822) rplK 902699..903121 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  CSB78_RS04635 (CSB78_0823) nusG 903302..903847 (-) 546 WP_001288304.1 transcription termination/antitermination protein NusG -
  CSB78_RS04640 (CSB78_0824) secE 903860..904042 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  CSB78_RS04645 (CSB78_0825) rpmG 904098..904241 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  CSB78_RS04650 (CSB78_0826) sigH 904356..904925 (-) 570 WP_000872882.1 RNA polymerase sigma factor Regulator
  CSB78_RS04655 (CSB78_0827) - 905006..905530 (-) 525 WP_000664737.1 NYN domain-containing protein -
  CSB78_RS04660 (CSB78_0828) rlmB 905530..906276 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  CSB78_RS04665 (CSB78_0829) - 906284..906688 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  CSB78_RS04670 (CSB78_0830) cysS 906681..908081 (-) 1401 WP_033863476.1 cysteine--tRNA ligase -
  CSB78_RS04675 (CSB78_0831) cysE 908065..908712 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23044.91 Da        Isoelectric Point: 9.4170

>NTDB_id=294958 CSB78_RS04650 WP_000872882.1 904356..904925(-) (sigH) [Staphylococcus aureus strain AR_0222]
MKYDLTTQDSTIKRNNSINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=294958 CSB78_RS04650 WP_000872882.1 904356..904925(-) (sigH) [Staphylococcus aureus strain AR_0222]
TTGAAATATGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATTCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

100

100

1
  sigH Staphylococcus aureus MW2

97.884

100

0.979

Multiple sequence alignment