Detailed information NTG0289177

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: DCE79_RS12260
• Genome accession: NZ_CP029002
• Coordinates: 2511915..2512388 (-)
• Length: 157 a.a.
• NCBI ID: WP_234417403.1
• Uniprot ID: -
• Organism: Lysinibacillus sp. 2017
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2506915..2517388

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DCE79_RS12235 (DCE79_12235)	rpsT	2507192..2507440 (+)	249	WP_108713319.1	30S ribosomal protein S20	-
DCE79_RS12240 (DCE79_12240)	holA	2507566..2508576 (-)	1011	WP_108713320.1	DNA polymerase III subunit delta	-
DCE79_RS12245 (DCE79_12245)	-	2508748..2508924 (+)	177	WP_108713321.1	YqzM family protein	-
DCE79_RS12250 (DCE79_12250)	-	2508965..2511286 (-)	2322	WP_108713322.1	DNA internalization-related competence protein ComEC/Rec2	-
DCE79_RS12255 (DCE79_12255)	-	2511255..2511830 (-)	576	WP_108713323.1	ComE operon protein 2	-
DCE79_RS12260 (DCE79_12260)	comEA	2511915..2512388 (-)	474	WP_234417403.1	helix-hairpin-helix domain-containing protein	Machinery gene
DCE79_RS12265 (DCE79_12265)	-	2512690..2513430 (-)	741	WP_108713325.1	class I SAM-dependent methyltransferase	-
DCE79_RS12270 (DCE79_12270)	rsfS	2513420..2513779 (-)	360	WP_108713326.1	ribosome silencing factor	-
DCE79_RS12275 (DCE79_12275)	yqeK	2513785..2514345 (-)	561	WP_108713327.1	bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK	-
DCE79_RS12280 (DCE79_12280)	-	2514314..2514904 (-)	591	WP_108713328.1	nicotinate-nucleotide adenylyltransferase	-
DCE79_RS12285 (DCE79_12285)	yhbY	2514916..2515221 (-)	306	WP_108713329.1	ribosome assembly RNA-binding protein YhbY	-
DCE79_RS12290 (DCE79_12290)	aroE	2515227..2516057 (-)	831	WP_108713330.1	shikimate dehydrogenase	-
DCE79_RS12295 (DCE79_12295)	yqeH	2516119..2517222 (-)	1104	WP_108713331.1	ribosome biogenesis GTPase YqeH	-

Sequence

Protein

• Length: 157 a.a.
• Molecular weight: 17073.26 Da
• Isoelectric Point: 4.4517

>NTDB_id=289177 DCE79_RS12260 WP_234417403.1 2511915..2512388(-) (comEA) [Lysinibacillus sp. 2017]
MDSSPQSIVVDVKGAVRYPGVYTLEDGQRIVDAIELAGGYIDQANPSIINHAQKLQDEMVIYIPKIGEEISETIEQLVQV
PQTTTSSSGSSKSGKINLNQADENGLTQLPGVGPSKAKAIIQYRTEQGQFQVIEDLKKVTGIGEKTFEQLKDLIDVK

Nucleotide

• Length: 474 bp

>NTDB_id=289177 DCE79_RS12260 WP_234417403.1 2511915..2512388(-) (comEA) [Lysinibacillus sp. 2017]
GTGGATAGCTCACCGCAATCTATAGTAGTTGATGTGAAGGGTGCTGTTCGCTATCCAGGCGTTTACACGCTTGAAGATGG
GCAACGAATTGTTGATGCTATTGAACTTGCTGGTGGTTACATCGATCAAGCAAATCCTTCTATAATTAATCATGCACAAA
AGTTGCAAGATGAGATGGTCATTTATATTCCGAAAATAGGTGAGGAGATAAGTGAAACAATCGAACAGTTGGTACAGGTA
CCGCAAACCACGACTTCCTCTAGCGGCTCTTCTAAATCTGGCAAAATCAACTTAAACCAAGCAGATGAAAATGGTTTAAC
ACAGCTGCCAGGAGTTGGTCCGTCGAAAGCAAAGGCTATTATTCAATACCGCACAGAACAAGGGCAGTTTCAAGTAATTG
AAGATTTAAAAAAAGTAACTGGTATAGGTGAAAAAACATTTGAGCAGTTAAAAGATTTAATTGATGTGAAATAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (9-63)

• Helix-hairpin-helix motif (HHH_3) (92-154)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Bacillus subtilis subsp. subtilis str. 168	48.718	99.363	0.484
comEA	Latilactobacillus sakei subsp. sakei 23K	45.455	100	0.478
comEA	Lactococcus lactis subsp. cremoris KW2	45.223	100	0.452
comEA/celA/cilE	Streptococcus mitis SK321	45.033	96.178	0.433
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	45.033	96.178	0.433
comEA/celA/cilE	Streptococcus pneumoniae Rx1	44.371	96.178	0.427
comEA/celA/cilE	Streptococcus pneumoniae D39	44.371	96.178	0.427
comEA/celA/cilE	Streptococcus pneumoniae R6	44.371	96.178	0.427
comEA/celA/cilE	Streptococcus mitis NCTC 12261	44.966	94.904	0.427
comEA	Staphylococcus aureus MW2	42.568	94.268	0.401
comEA	Staphylococcus aureus N315	43.056	91.72	0.395
comEA	Streptococcus thermophilus LMD-9	41.379	92.357	0.382