Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGC/cglC   Type   Machinery gene
Locus tag   C2E46_RS01140 Genome accession   NZ_CP026082
Coordinates   199058..199387 (+) Length   109 a.a.
NCBI ID   WP_000793380.1    Uniprot ID   A0A0E1EKJ1
Organism   Streptococcus agalactiae strain YZ1605     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 194058..204387
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  C2E46_RS01120 (C2E46_01130) - 195053..195418 (+) 366 WP_000285374.1 DUF1033 family protein -
  C2E46_RS01125 (C2E46_01135) - 195647..197107 (+) 1461 WP_000468685.1 IS1182-like element IS1563 family transposase -
  C2E46_RS01130 (C2E46_01140) comYA 197153..198124 (+) 972 WP_000250798.1 competence type IV pilus ATPase ComGA Machinery gene
  C2E46_RS01135 (C2E46_01145) comYB 198018..199061 (+) 1044 WP_223297804.1 competence type IV pilus assembly protein ComGB Machinery gene
  C2E46_RS01140 (C2E46_01150) comGC/cglC 199058..199387 (+) 330 WP_000793380.1 competence type IV pilus major pilin ComGC Machinery gene
  C2E46_RS01145 (C2E46_01155) comYD 199362..199775 (+) 414 WP_000244259.1 competence type IV pilus minor pilin ComGD Machinery gene
  C2E46_RS01150 (C2E46_01160) comGE 199747..200046 (+) 300 WP_001872488.1 competence type IV pilus minor pilin ComGE -
  C2E46_RS01155 (C2E46_01165) comGF 200000..200461 (+) 462 WP_001874060.1 competence type IV pilus minor pilin ComGF -
  C2E46_RS01160 (C2E46_01170) comGG 200439..200810 (+) 372 WP_000601101.1 competence type IV pilus minor pilin ComGG -
  C2E46_RS01165 (C2E46_01175) comYH 200925..201899 (+) 975 WP_001008569.1 class I SAM-dependent methyltransferase Machinery gene
  C2E46_RS01170 (C2E46_01180) - 201931..203124 (+) 1194 WP_000047534.1 acetate kinase -

Sequence

Protein


Download         Length: 109 a.a.        Molecular weight: 12129.27 Da        Isoelectric Point: 10.0311

>NTDB_id=266882 C2E46_RS01140 WP_000793380.1 199058..199387(+) (comGC/cglC) [Streptococcus agalactiae strain YZ1605]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide


Download         Length: 330 bp        

>NTDB_id=266882 C2E46_RS01140 WP_000793380.1 199058..199387(+) (comGC/cglC) [Streptococcus agalactiae strain YZ1605]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTACCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(11-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1EKJ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGC/cglC Streptococcus mitis NCTC 12261

60.55

100

0.606
  comGC/cglC Streptococcus mitis SK321

59.633

100

0.596
  comYC Streptococcus gordonii str. Challis substr. CH1

61.165

94.495

0.578
  comGC/cglC Streptococcus pneumoniae TIGR4

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae R6

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae Rx1

57.798

100

0.578
  comGC/cglC Streptococcus pneumoniae D39

57.798

100

0.578
  comYC Streptococcus mutans UA159

55.238

96.33

0.532
  comYC Streptococcus mutans UA140

55.238

96.33

0.532
  comGC Lactococcus lactis subsp. cremoris KW2

63.043

84.404

0.532
  comYC Streptococcus suis isolate S10

65.854

75.229

0.495

Multiple sequence alignment