Detailed information NTG0266880

Bioinformatically predicted

Overview

• Name: comYA
• Type: Machinery gene
• Locus tag: C2E46_RS01130
• Genome accession: NZ_CP026082
• Coordinates: 197153..198124 (+)
• Length: 323 a.a.
• NCBI ID: WP_000250798.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain YZ1605
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	195647..197107	197153..198124	flank	46

Gene organization within MGE regions

Location: 195647..198124

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2E46_RS01125 (C2E46_01135)	-	195647..197107 (+)	1461	WP_000468685.1	IS1182-like element IS1563 family transposase	-
C2E46_RS01130 (C2E46_01140)	comYA	197153..198124 (+)	972	WP_000250798.1	competence type IV pilus ATPase ComGA	Machinery gene

Sequence

Protein

• Length: 323 a.a.
• Molecular weight: 36768.25 Da
• Isoelectric Point: 6.9167

>NTDB_id=266880 C2E46_RS01130 WP_000250798.1 197153..198124(+) (comYA) [Streptococcus agalactiae strain YZ1605]
MVQSLAKHVIHQAVEVNAQDIYIIPKGDCYELYMRIDDERRFIDVFEFNRMASLISHFKFVAGMNVGEKRRSQLGSCDYE
LSEGRLVSLRLSSVGDYRGQESLVIRILYSGHQDLKYWFDNIKQMKEVLGARGLYLFSGPVGSGKTTLMYQLASEVFKNK
QIITIEDPVEIKNDKMLQLQLNEDIGMTYDALIKLSLRHRPDILIIGEIRDQATARAVIRASLTGVMVFSTIHAKSIPGV
YDRLIELGVNYQELENSLKLIAYQRLIGGGSLIDFETGNFKKHSSDKWNRQVDILAEEGHISKKQAQVEKIIPQETTESS
PTF

Nucleotide

• Length: 972 bp

>NTDB_id=266880 C2E46_RS01130 WP_000250798.1 197153..198124(+) (comYA) [Streptococcus agalactiae strain YZ1605]
ATGGTTCAATCATTAGCAAAGCACGTCATCCATCAGGCAGTAGAAGTAAATGCTCAAGATATTTATATCATTCCCAAAGG
TGATTGTTATGAACTCTATATGCGTATTGATGATGAAAGGCGGTTTATTGATGTTTTTGAGTTTAATAGGATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGCATGAACGTTGGAGAAAAAAGACGAAGTCAATTAGGTTCTTGTGACTATGAA
CTGTCAGAGGGAAGACTGGTTTCATTACGACTATCAAGTGTGGGAGATTATCGTGGTCAAGAATCTTTAGTTATTCGTAT
TTTGTATTCAGGTCATCAGGACTTAAAATATTGGTTTGATAATATAAAGCAAATGAAGGAAGTACTGGGTGCAAGAGGGC
TATATCTTTTTTCCGGCCCTGTGGGGAGTGGTAAAACAACTCTCATGTATCAATTAGCTTCAGAAGTATTTAAAAATAAG
CAAATTATCACGATTGAAGATCCGGTAGAAATCAAGAATGACAAGATGTTACAACTCCAATTGAATGAGGATATTGGAAT
GACTTATGATGCTTTAATCAAACTGTCTTTACGGCATCGTCCAGATATTTTAATTATCGGAGAGATTAGAGATCAAGCGA
CGGCCCGTGCTGTTATTCGTGCAAGTTTAACGGGAGTGATGGTTTTTTCTACTATTCATGCTAAAAGTATTCCCGGAGTC
TATGATAGGCTTATAGAATTAGGGGTTAACTATCAAGAGTTAGAAAATAGTCTAAAATTAATAGCATATCAACGTTTAAT
TGGAGGAGGAAGCCTAATTGACTTTGAGACAGGTAATTTTAAAAAACACTCATCAGACAAGTGGAATAGACAAGTGGATA
TCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAAACAACGGAAAGTAGT
CCAACTTTTTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (9-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYA	Streptococcus mutans UA159	68.81	96.285	0.663
comYA	Streptococcus mutans UA140	68.81	96.285	0.663
comYA	Streptococcus gordonii str. Challis substr. CH1	63.636	98.762	0.628
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	62.701	96.285	0.604
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	61.736	96.285	0.594
comGA/cglA/cilD	Streptococcus pneumoniae D39	61.736	96.285	0.594
comGA/cglA/cilD	Streptococcus pneumoniae R6	61.736	96.285	0.594
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	61.736	96.285	0.594
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	61.935	95.975	0.594
comGA	Lactococcus lactis subsp. cremoris KW2	50.621	99.69	0.505