Detailed information NTG0266881

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: C2E46_RS01135
• Genome accession: NZ_CP026082
• Coordinates: 198018..199061 (+)
• Length: 347 a.a.
• NCBI ID: WP_223297804.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae strain YZ1605
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	195647..197107	198018..199061	flank	911

Gene organization within MGE regions

Location: 195647..199061

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
C2E46_RS01125 (C2E46_01135)	-	195647..197107 (+)	1461	WP_000468685.1	IS1182-like element IS1563 family transposase	-
C2E46_RS01130 (C2E46_01140)	comYA	197153..198124 (+)	972	WP_000250798.1	competence type IV pilus ATPase ComGA	Machinery gene
C2E46_RS01135 (C2E46_01145)	comYB	198018..199061 (+)	1044	WP_223297804.1	competence type IV pilus assembly protein ComGB	Machinery gene

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40014.77 Da
• Isoelectric Point: 9.9642

>NTDB_id=266881 C2E46_RS01135 WP_223297804.1 198018..199061(+) (comYB) [Streptococcus agalactiae strain YZ1605]
MDKWISWLKKDISVRNRHKSKKLSLKKQRKVVQLFNNLFASGFSLTDMVTFLKRSKLLSDCYTDRMNKALLEGKDLSKML
GELGFSDTVITQVALADLHGNISRSLLKIESYLANLLLVRKKVIEVATYPLILLSFLVLIMIGLRHYLMPQLGENNFATR
LITNVPNIFLLLLAVVLIFSLIFYIIQKRLSRIKVACFLTTIPLVGSYVKLYLTAYYAREWGNLLSQGVELDQIVKVMQN
QKSKLFREIGYDMEEGFLSGKAFHQKVLDYPFFLTELSLMIEYGQVKAKLGTELDIYADEKWEDFFTKLARATQLIQPVI
FIFVALIIVMIYAAMLLPMYQNMEILS

Nucleotide

• Length: 1044 bp

>NTDB_id=266881 C2E46_RS01135 WP_223297804.1 198018..199061(+) (comYB) [Streptococcus agalactiae strain YZ1605]
ATAGACAAGTGGATATCTTGGCTGAAGAAGGACATATCAGTAAGAAACAGGCACAAGTCGAAAAAATTATCCCTCAAGAA
ACAACGGAAAGTAGTCCAACTTTTTAATAATCTTTTTGCTAGTGGTTTTTCTTTAACTGATATGGTCACCTTCTTAAAGA
GGAGTAAGTTATTGTCTGATTGTTATACAGATAGGATGAATAAGGCATTATTAGAGGGAAAAGATTTATCAAAAATGTTA
GGAGAGTTAGGTTTTTCTGACACTGTTATCACACAGGTTGCATTAGCTGATTTGCATGGTAACATTTCAAGGAGCCTACT
AAAGATTGAGTCTTATTTAGCTAATCTTTTGTTAGTTAGAAAAAAAGTAATAGAAGTAGCTACTTACCCATTGATATTAT
TGTCTTTTCTGGTGCTAATTATGATTGGCCTTAGGCATTATTTAATGCCCCAATTAGGAGAAAATAATTTTGCAACTAGA
CTGATTACAAATGTGCCGAATATTTTCTTATTACTTTTAGCAGTTGTACTTATTTTTAGTTTAATATTTTATATTATTCA
AAAGCGATTGTCGCGCATTAAAGTAGCTTGTTTTTTAACAACAATTCCCTTAGTTGGATCATATGTTAAGCTTTATTTAA
CTGCTTACTATGCCCGTGAGTGGGGAAATTTATTAAGTCAAGGTGTTGAATTGGACCAAATTGTTAAAGTAATGCAAAAT
CAGAAATCCAAACTTTTTAGGGAAATAGGATATGACATGGAAGAAGGTTTTCTATCAGGTAAAGCATTTCACCAAAAAGT
ATTAGACTATCCGTTTTTCTTAACTGAGCTTAGTTTAATGATTGAATATGGTCAAGTTAAGGCGAAATTAGGAACAGAGT
TAGATATATATGCTGATGAGAAGTGGGAGGATTTTTTTACAAAATTAGCTAGAGCGACCCAGTTAATCCAACCTGTTATT
TTTATTTTTGTAGCTCTTATCATTGTTATGATTTATGCAGCAATGCTGTTACCAATGTATCAAAATATGGAGATATTATC
ATGA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (218-338)

• Type II secretion system (T2SS), protein F (T2SSF) (33-150)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	62.17	98.271	0.611
comYB	Streptococcus mutans UA159	61.877	98.271	0.608
comYB	Streptococcus gordonii str. Challis substr. CH1	56.012	98.271	0.55
comGB/cglB	Streptococcus mitis NCTC 12261	54.925	96.542	0.53
comGB/cglB	Streptococcus mitis SK321	54.328	96.542	0.524
comGB/cglB	Streptococcus pneumoniae Rx1	53.433	96.542	0.516
comGB/cglB	Streptococcus pneumoniae D39	53.433	96.542	0.516
comGB/cglB	Streptococcus pneumoniae R6	53.433	96.542	0.516
comGB/cglB	Streptococcus pneumoniae TIGR4	53.433	96.542	0.516
comGB	Lactococcus lactis subsp. cremoris KW2	50.148	97.118	0.487