Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   CK207_RS00375 Genome accession   NZ_CP023054
Coordinates   73018..74127 (+) Length   369 a.a.
NCBI ID   WP_019283081.1    Uniprot ID   A0A289G7Y8
Organism   Vibrio anguillarum strain VIB43     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 68018..79127
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CK207_RS00355 (CK207_00355) rsmB 68934..70214 (-) 1281 WP_019283078.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  CK207_RS00360 (CK207_00360) fmt 70274..71221 (-) 948 WP_019283079.1 methionyl-tRNA formyltransferase -
  CK207_RS00365 (CK207_00365) def 71238..71747 (-) 510 WP_043004842.1 peptide deformylase -
  CK207_RS00370 (CK207_00370) - 71888..73018 (+) 1131 WP_069212091.1 LysM peptidoglycan-binding domain-containing protein -
  CK207_RS00375 (CK207_00375) dprA 73018..74127 (+) 1110 WP_019283081.1 DNA-processing protein DprA Machinery gene
  CK207_RS00380 (CK207_00380) - 74130..74606 (+) 477 WP_019283082.1 DUF494 family protein -
  CK207_RS00385 (CK207_00385) - 74634..75206 (+) 573 WP_029388412.1 type I DNA topoisomerase -
  CK207_RS00390 (CK207_00390) - 75279..76418 (-) 1140 WP_019283084.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  CK207_RS00395 (CK207_00395) purE 76423..76908 (-) 486 WP_010319910.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  CK207_RS00400 (CK207_00400) - 77109..77666 (+) 558 WP_010319909.1 L-threonylcarbamoyladenylate synthase -
  CK207_RS00405 (CK207_00405) hemF 77687..78601 (+) 915 WP_010319908.1 oxygen-dependent coproporphyrinogen oxidase -

Sequence

Protein


Download         Length: 369 a.a.        Molecular weight: 39821.50 Da        Isoelectric Point: 6.2355

>NTDB_id=244586 CK207_RS00375 WP_019283081.1 73018..74127(+) (dprA) [Vibrio anguillarum strain VIB43]
MEQNELAAWLAFSFVPKLGGKKLSRLASVASLAHLIDYSEQELAALGLVQEQIRYLRETAPQEVEECLSWQQAHESHYIL
TPFCDGYPSLLKEIATVPPVLFVKGRITALSDPQMAIVGSRNASPDGQRVAHQFAREFVQQGLVVTSGLALGIDGHAHDG
ALQAGGETIAVLGSGLESIYPARHKKLAQRVMESGALVSEFRPKAKPRPDNFPRRNRIISGLAVGVLVVEAAEKSGSLIT
ARYAAEQGRDVFVIPGSIANPNCHGSNQLIRCGACLVQNSEQVLSEIGTLVDWSLRQKSPQPDLFSAQSDQQLPFAELLA
NVGVEATPVDILASRTDTPVHEVMMQLLELELSGYVVAVSGGYIRKGKG

Nucleotide


Download         Length: 1110 bp        

>NTDB_id=244586 CK207_RS00375 WP_019283081.1 73018..74127(+) (dprA) [Vibrio anguillarum strain VIB43]
ATGGAGCAGAACGAATTAGCGGCGTGGCTAGCATTCAGCTTTGTGCCCAAATTGGGTGGCAAGAAACTTTCTCGCCTTGC
TAGCGTCGCTTCTCTTGCTCATTTAATTGACTATTCCGAGCAGGAGTTAGCCGCGTTGGGTCTAGTTCAAGAGCAAATCC
GTTATCTGCGCGAGACGGCCCCTCAAGAAGTTGAAGAATGCCTAAGTTGGCAGCAAGCTCATGAGTCTCATTACATCCTT
ACTCCATTTTGCGATGGTTACCCTTCTTTACTAAAAGAAATTGCTACCGTACCTCCGGTTTTATTTGTCAAAGGACGAAT
AACAGCACTCTCTGATCCGCAAATGGCGATCGTCGGCAGTCGTAATGCGAGCCCTGATGGCCAACGAGTTGCTCATCAGT
TTGCGCGAGAATTTGTGCAACAGGGCTTGGTAGTCACCAGTGGTTTGGCATTAGGTATTGATGGACATGCTCATGACGGT
GCGTTGCAAGCGGGTGGTGAGACGATTGCCGTGCTCGGTTCGGGCCTTGAATCTATTTACCCAGCGCGGCATAAAAAATT
AGCGCAACGGGTGATGGAAAGCGGAGCATTAGTCTCGGAATTTCGCCCCAAAGCCAAACCAAGGCCGGATAACTTTCCGC
GGCGCAATCGCATTATCAGCGGGTTAGCGGTTGGTGTTTTAGTGGTGGAAGCGGCGGAGAAAAGTGGCTCGTTGATCACG
GCGCGTTATGCGGCTGAGCAAGGGCGAGATGTGTTTGTTATTCCGGGCTCAATTGCCAACCCAAATTGCCACGGTAGTAA
TCAACTTATTCGTTGTGGGGCGTGCTTGGTGCAAAACAGTGAACAAGTATTGTCCGAAATTGGCACCTTAGTGGATTGGT
CATTGCGTCAAAAGTCGCCTCAACCGGATTTATTTTCAGCTCAGAGCGATCAGCAATTGCCATTTGCTGAACTGTTAGCT
AACGTAGGAGTAGAGGCTACGCCTGTTGATATTCTTGCGAGCAGGACCGATACACCTGTCCATGAAGTCATGATGCAGCT
TTTAGAGCTTGAGCTTTCAGGTTATGTTGTTGCCGTTTCTGGCGGCTATATTCGTAAAGGGAAGGGTTAG

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(313-362)

DNA recombination-mediator protein A (DNA_processg_A)

(78-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A289G7Y8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio campbellii strain DS40M4

63.661

99.187

0.631
  dprA Vibrio cholerae strain A1552

61.725

100

0.621
  dprA Glaesserella parasuis strain SC1401

45.093

100

0.461
  dprA Legionella pneumophila strain ERS1305867

43.526

98.374

0.428
  dprA Neisseria meningitidis MC58

37.468

100

0.401
  dprA Neisseria meningitidis strain C311

37.468

100

0.401
  dprA Neisseria gonorrhoeae MS11

35.878

100

0.382
  dprA Acinetobacter baumannii D1279779

39.943

95.664

0.382
  dprA Neisseria gonorrhoeae strain FA1090

35.623

100

0.379
  dprA Acinetobacter baumannii strain A118

39.045

96.477

0.377
  dprA Haemophilus influenzae Rd KW20

50

74.255

0.371
  dprA Acinetobacter baylyi ADP1

40.483

89.702

0.363

Multiple sequence alignment