Detailed information NTG0023020

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: GBS_RS01080
• Genome accession: NC_004368
• Coordinates: 189092..189421 (+)
• Length: 109 a.a.
• NCBI ID: WP_000793380.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae NEM316
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 184092..194421

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GBS_RS01070 (gbs0158)	-	186649..187014 (+)	366	WP_000285373.1	DUF1033 family protein	-
GBS_RS11090	comGA	187187..188158 (+)	972	WP_000250808.1	competence type IV pilus ATPase ComGA	Machinery gene
GBS_RS01075 (gbs0160)	comGB	188052..189095 (+)	1044	WP_223295592.1	competence type IV pilus assembly protein ComGB	Machinery gene
GBS_RS01080 (gbs0161)	comGC/cglC	189092..189421 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
GBS_RS01085 (gbs0162)	comGD	189396..189809 (+)	414	WP_000244259.1	competence type IV pilus minor pilin ComGD	Machinery gene
GBS_RS01090 (gbs0163)	comGE	189781..190080 (+)	300	WP_001867089.1	competence type IV pilus minor pilin ComGE	Machinery gene
GBS_RS01095 (gbs0164)	comGF	190034..190495 (+)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	Machinery gene
GBS_RS01100 (gbs0165)	comGG	190473..190844 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
GBS_RS01105 (gbs0166)	comGH	190959..191933 (+)	975	WP_001008570.1	class I SAM-dependent methyltransferase	Machinery gene
GBS_RS01110 (gbs0167)	-	191965..193158 (+)	1194	WP_000047535.1	acetate kinase	-
GBS_RS01115 (gbs0168)	-	193309..193515 (+)	207	WP_000798242.1	helix-turn-helix transcriptional regulator	-
GBS_RS11710	-	193574..193711 (+)	138	WP_001867090.1	hypothetical protein	-
GBS_RS01120 (gbs0169)	-	193752..194207 (+)	456	WP_000905674.1	hypothetical protein	-

Sequence

Protein

• Length: 109 a.a.
• Molecular weight: 12129.27 Da
• Isoelectric Point: 10.0311

>NTDB_id=23020 GBS_RS01080 WP_000793380.1 189092..189421(+) (comGC/cglC) [Streptococcus agalactiae NEM316]
MKNLLLKCKDKKVKAFTLLEMLVVLIIISVLLLLFVPNLSKQKESVTRTGNAAVVKVVESQAELFELQETGRKASLSTLK
SGGYITEKQEKAYLDYYKDSSNGSQKISS

Nucleotide

• Length: 330 bp

>NTDB_id=23020 GBS_RS01080 WP_000793380.1 189092..189421(+) (comGC/cglC) [Streptococcus agalactiae NEM316]
ATGAAAAATTTATTGTTAAAATGTAAGGATAAGAAGGTTAAAGCATTTACACTTTTAGAAATGTTAGTTGTTTTGATCAT
TATTTCGGTCTTGTTGTTATTGTTTGTGCCCAATTTATCAAAACAAAAGGAAAGTGTCACAAGAACTGGAAATGCCGCTG
TTGTCAAGGTTGTAGAAAGTCAAGCCGAACTTTTTGAACTGCAAGAAACAGGTAGAAAAGCTAGTTTATCCACTCTAAAA
TCTGGAGGATATATTACTGAAAAGCAAGAAAAAGCCTATTTAGATTATTATAAAGACAGTTCCAATGGTTCTCAGAAAAT
TTCAAGTTAA

Domains

Predicted by InterProScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus mitis NCTC 12261	60.55	100	0.606
comGC/cglC	Streptococcus mitis SK321	59.633	100	0.596
comGC	Streptococcus gordonii str. Challis substr. CH1	61.165	94.495	0.578
comGC/cglC	Streptococcus pneumoniae TIGR4	57.798	100	0.578
comGC/cglC	Streptococcus pneumoniae R6	57.798	100	0.578
comGC/cglC	Streptococcus pneumoniae Rx1	57.798	100	0.578
comGC/cglC	Streptococcus pneumoniae D39	57.798	100	0.578
comGC	Streptococcus mutans UA159	55.238	96.33	0.532
comGC	Streptococcus mutans UA140	55.238	96.33	0.532
comGC	Lactococcus lactis subsp. cremoris KW2	63.043	84.404	0.532
comGC	Streptococcus suis isolate S10	65.854	75.229	0.495