Detailed information NTG0023023

Bioinformatically predicted

Overview

• Name: comGF
• Type: Machinery gene
• Locus tag: GBS_RS01095
• Genome accession: NC_004368
• Coordinates: 190034..190495 (+)
• Length: 153 a.a.
• NCBI ID: WP_001874060.1
• Uniprot ID: -
• Organism: Streptococcus agalactiae NEM316
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 185034..195495

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
GBS_RS01070 (gbs0158)	-	186649..187014 (+)	366	WP_000285373.1	DUF1033 family protein	-
GBS_RS11090	comGA	187187..188158 (+)	972	WP_000250808.1	competence type IV pilus ATPase ComGA	Machinery gene
GBS_RS01075 (gbs0160)	comGB	188052..189095 (+)	1044	WP_223295592.1	competence type IV pilus assembly protein ComGB	Machinery gene
GBS_RS01080 (gbs0161)	comGC/cglC	189092..189421 (+)	330	WP_000793380.1	competence type IV pilus major pilin ComGC	Machinery gene
GBS_RS01085 (gbs0162)	comGD	189396..189809 (+)	414	WP_000244259.1	competence type IV pilus minor pilin ComGD	Machinery gene
GBS_RS01090 (gbs0163)	comGE	189781..190080 (+)	300	WP_001867089.1	competence type IV pilus minor pilin ComGE	Machinery gene
GBS_RS01095 (gbs0164)	comGF	190034..190495 (+)	462	WP_001874060.1	competence type IV pilus minor pilin ComGF	Machinery gene
GBS_RS01100 (gbs0165)	comGG	190473..190844 (+)	372	WP_000601104.1	competence type IV pilus minor pilin ComGG	Machinery gene
GBS_RS01105 (gbs0166)	comGH	190959..191933 (+)	975	WP_001008570.1	class I SAM-dependent methyltransferase	Machinery gene
GBS_RS01110 (gbs0167)	-	191965..193158 (+)	1194	WP_000047535.1	acetate kinase	-
GBS_RS01115 (gbs0168)	-	193309..193515 (+)	207	WP_000798242.1	helix-turn-helix transcriptional regulator	-
GBS_RS11710	-	193574..193711 (+)	138	WP_001867090.1	hypothetical protein	-
GBS_RS01120 (gbs0169)	-	193752..194207 (+)	456	WP_000905674.1	hypothetical protein	-
GBS_RS01125 (gbs0170)	-	194276..194941 (+)	666	WP_000008111.1	CPBP family intramembrane glutamic endopeptidase	-

Sequence

Protein

• Length: 153 a.a.
• Molecular weight: 17861.86 Da
• Isoelectric Point: 9.8392

>NTDB_id=23023 GBS_RS01095 WP_001874060.1 190034..190495(+) (comGF) [Streptococcus agalactiae NEM316]
MKVIRKFCTYQKLRVKAFTLLECLVALVTITGALLVYQGLTKLLAQQIVVMSSSSQSEWVLLTQQLNAEFEGAHLEYLRQ
NKLYLRKQDKIVTFGKSNKDDFRKTGYDGRGYQPMVYGLDNCQMSQTKSMVKLVFYFKDGLKRTFYYDFKEET

Nucleotide

• Length: 462 bp

>NTDB_id=23023 GBS_RS01095 WP_001874060.1 190034..190495(+) (comGF) [Streptococcus agalactiae NEM316]
TTGAAGGTAATAAGGAAATTTTGCACGTATCAAAAGTTAAGGGTTAAAGCATTTACGCTTTTAGAATGTTTGGTAGCATT
GGTTACAATCACAGGAGCTTTACTAGTTTATCAAGGACTGACAAAATTGTTGGCTCAACAGATAGTAGTGATGTCTTCTT
CCAGTCAGTCTGAATGGGTGTTATTAACTCAGCAACTAAATGCAGAATTCGAAGGCGCTCACTTGGAATATTTAAGACAG
AACAAACTTTATTTACGTAAGCAAGATAAGATTGTAACCTTTGGCAAATCTAATAAAGATGATTTCCGTAAGACAGGTTA
TGATGGTCGAGGTTATCAACCAATGGTTTATGGGTTAGACAATTGTCAAATGAGTCAAACCAAAAGTATGGTAAAACTTG
TTTTTTATTTTAAGGACGGGTTAAAAAGGACATTTTACTATGATTTTAAAGAAGAAACTTAA

Domains

Predicted by InterProScan.

• Putative Competence protein ComGF (ComGF) (49-142)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF	Streptococcus mutans UA159	47.887	92.81	0.444
comGF	Streptococcus mutans UA140	47.887	92.81	0.444
comGF/cglF	Streptococcus pneumoniae Rx1	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae D39	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae R6	43.165	90.85	0.392
comGF/cglF	Streptococcus pneumoniae TIGR4	43.165	90.85	0.392
comGF/cglF	Streptococcus mitis SK321	44.03	87.582	0.386
comGF/cglF	Streptococcus mitis NCTC 12261	43.284	87.582	0.379
comGF	Lactococcus lactis subsp. cremoris KW2	40.714	91.503	0.373