Detailed information    

insolico Bioinformatically predicted

Overview


Name   ssbA   Type   Machinery gene
Locus tag   SPYM18_RS07730 Genome accession   NC_003485
Coordinates   1483437..1483856 (-) Length   139 a.a.
NCBI ID   WP_011018140.1    Uniprot ID   -
Organism   Streptococcus pyogenes MGAS8232     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1451844..1493373 1483437..1483856 within 0


Gene organization within MGE regions


Location: 1451844..1493373
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPYM18_RS07505 (spyM18_1745) prx 1451844..1452026 (-) 183 WP_011018104.1 hypothetical protein Regulator
  SPYM18_RS07510 (spyM18_1746) sda 1452266..1453264 (+) 999 WP_011018105.1 streptodornase A -
  SPYM18_RS07515 (spyM18_1747) - 1453405..1453965 (-) 561 WP_011018106.1 GNAT family N-acetyltransferase -
  SPYM18_RS07520 (spyM18_1749) - 1453998..1454162 (-) 165 WP_021340366.1 hypothetical protein -
  SPYM18_RS07525 (spyM18_1750) - 1454311..1455516 (-) 1206 WP_011018108.1 glucosaminidase domain-containing protein -
  SPYM18_RS07535 - 1455629..1455823 (-) 195 WP_023079604.1 hypothetical protein -
  SPYM18_RS07540 (spyM18_1753) - 1455820..1456119 (-) 300 WP_011018110.1 hypothetical protein -
  SPYM18_RS07545 (spyM18_1754) - 1456130..1456747 (-) 618 WP_011018111.1 DUF1366 domain-containing protein -
  SPYM18_RS07550 (spyM18_1755) - 1456750..1457178 (-) 429 WP_011018112.1 DUF1617 family protein -
  SPYM18_RS07555 (spyM18_1756) - 1457190..1459205 (-) 2016 WP_011018113.1 gp58-like family protein -
  SPYM18_RS07560 (spyM18_1757) - 1459220..1460329 (-) 1110 WP_011018114.1 hyaluronoglucosaminidase -
  SPYM18_RS07565 - 1460329..1462308 (-) 1980 WP_041174241.1 phage tail spike protein -
  SPYM18_RS10775 (spyM18_1761) - 1462316..1462474 (-) 159 WP_011018115.1 hypothetical protein -
  SPYM18_RS07570 (spyM18_1762) - 1462471..1463187 (-) 717 WP_011018116.1 distal tail protein Dit -
  SPYM18_RS07575 (spyM18_1763) - 1463184..1466444 (-) 3261 WP_011018117.1 tape measure protein -
  SPYM18_RS07580 (spyM18_1764) - 1466434..1467015 (-) 582 WP_011018118.1 bacteriophage Gp15 family protein -
  SPYM18_RS07585 (spyM18_1765) - 1467019..1467453 (-) 435 WP_011018119.1 hypothetical protein -
  SPYM18_RS07590 (spyM18_1766) - 1467497..1467958 (-) 462 WP_011018120.1 phage tail tube protein -
  SPYM18_RS07595 (spyM18_1767) - 1467958..1468356 (-) 399 WP_011018121.1 minor capsid protein -
  SPYM18_RS07600 (spyM18_1769) - 1468353..1468709 (-) 357 WP_010922083.1 minor capsid protein -
  SPYM18_RS07605 (spyM18_1770) - 1468709..1469041 (-) 333 WP_010922082.1 minor capsid protein -
  SPYM18_RS07610 (spyM18_1771) - 1469031..1469447 (-) 417 WP_011018123.1 hypothetical protein -
  SPYM18_RS07615 (spyM18_1772) - 1469501..1470319 (-) 819 WP_010922080.1 N4-gp56 family major capsid protein -
  SPYM18_RS07620 (spyM18_1774) - 1470323..1470937 (-) 615 WP_010922079.1 hypothetical protein -
  SPYM18_RS07625 (spyM18_1775) - 1471063..1471329 (-) 267 WP_010922078.1 hypothetical protein -
  SPYM18_RS07630 (spyM18_1776) - 1471416..1471643 (-) 228 WP_010922077.1 hypothetical protein -
  SPYM18_RS07635 (spyM18_1777) - 1471643..1473136 (-) 1494 WP_011018124.1 phage minor capsid protein -
  SPYM18_RS07640 (spyM18_1778) - 1473141..1474643 (-) 1503 WP_011184804.1 phage portal protein -
  SPYM18_RS07645 (spyM18_1779) - 1474657..1475948 (-) 1292 Protein_1485 PBSX family phage terminase large subunit -
  SPYM18_RS07650 (spyM18_1780) - 1475951..1476424 (-) 474 WP_011018127.1 hypothetical protein -
  SPYM18_RS07655 (spyM18_1781) - 1476475..1476852 (-) 378 WP_002986841.1 ASCH domain-containing protein -
  SPYM18_RS10005 (spyM18_1782) - 1476913..1477389 (-) 477 WP_174148345.1 GNAT family N-acetyltransferase -
  SPYM18_RS07665 (spyM18_1783) - 1477305..1477982 (-) 678 WP_011018129.1 ABC transporter ATP-binding protein -
  SPYM18_RS07670 (spyM18_1784) - 1477961..1478479 (-) 519 WP_011018130.1 ParB N-terminal domain-containing protein -
  SPYM18_RS07675 (spyM18_1785) - 1478943..1479383 (-) 441 WP_002990052.1 ArpU family phage packaging/lysis transcriptional regulator -
  SPYM18_RS07680 (spyM18_1786) - 1479657..1479923 (-) 267 WP_011018131.1 hypothetical protein -
  SPYM18_RS07685 (spyM18_1787) - 1479920..1480291 (-) 372 WP_011018132.1 DUF1642 domain-containing protein -
  SPYM18_RS07690 (spyM18_1788) - 1480412..1481044 (-) 633 WP_011018133.1 N-6 DNA methylase -
  SPYM18_RS07695 (spyM18_1789) - 1481046..1481330 (-) 285 WP_011018134.1 hypothetical protein -
  SPYM18_RS10375 (spyM18_1790) - 1481341..1481511 (-) 171 WP_011018135.1 hypothetical protein -
  SPYM18_RS07700 (spyM18_1791) - 1481508..1481912 (-) 405 WP_011018136.1 YopX family protein -
  SPYM18_RS07705 (spyM18_1792) - 1481909..1482193 (-) 285 WP_011018137.1 DUF3310 domain-containing protein -
  SPYM18_RS10695 - 1482187..1482438 (-) 252 WP_011106665.1 hypothetical protein -
  SPYM18_RS07715 (spyM18_1793) - 1482435..1482791 (-) 357 WP_011018138.1 hypothetical protein -
  SPYM18_RS07720 (spyM18_1794) - 1482788..1483228 (-) 441 WP_011018139.1 RusA family crossover junction endodeoxyribonuclease -
  SPYM18_RS07725 - 1483228..1483431 (-) 204 WP_032465709.1 hypothetical protein -
  SPYM18_RS07730 (spyM18_1795) ssbA 1483437..1483856 (-) 420 WP_011018140.1 single-stranded DNA-binding protein Machinery gene
  SPYM18_RS07735 (spyM18_1796) - 1483849..1484523 (-) 675 WP_011018141.1 ERF family protein -
  SPYM18_RS07740 (spyM18_1797) - 1484524..1485006 (-) 483 WP_011018142.1 siphovirus Gp157 family protein -
  SPYM18_RS07745 (spyM18_1798) - 1485028..1485282 (-) 255 WP_011018143.1 hypothetical protein -
  SPYM18_RS07750 (spyM18_1799) - 1485263..1485619 (-) 357 WP_011018144.1 HTH domain-containing protein -
  SPYM18_RS10380 (spyM18_1800) - 1485630..1485767 (-) 138 WP_011018145.1 hypothetical protein -
  SPYM18_RS07755 (spyM18_1801) - 1485767..1486609 (-) 843 WP_011018146.1 ATP-binding protein -
  SPYM18_RS07760 (spyM18_1803) - 1486619..1487557 (-) 939 WP_011018147.1 phage replisome organizer N-terminal domain-containing protein -
  SPYM18_RS10780 (spyM18_1804) - 1487571..1487884 (-) 314 Protein_1511 helix-turn-helix domain-containing protein -
  SPYM18_RS07775 - 1488066..1488317 (-) 252 WP_021340237.1 helix-turn-helix transcriptional regulator -
  SPYM18_RS10385 - 1488556..1488723 (-) 168 WP_021340232.1 hypothetical protein -
  SPYM18_RS07785 (spyM18_1802) - 1488727..1489446 (-) 720 WP_011018149.1 phage antirepressor KilAC domain-containing protein -
  SPYM18_RS07790 - 1489474..1489686 (-) 213 WP_014635614.1 DNA-binding protein -
  SPYM18_RS07795 (spyM18_1805) - 1489882..1490223 (+) 342 WP_011888679.1 helix-turn-helix domain-containing protein -
  SPYM18_RS07800 - 1490207..1490593 (+) 387 WP_032463929.1 ImmA/IrrE family metallo-endopeptidase -
  SPYM18_RS07805 (spyM18_1806) - 1490608..1492029 (+) 1422 WP_011018151.1 DUF4041 domain-containing protein -
  SPYM18_RS07810 (spyM18_1808) - 1492207..1493373 (+) 1167 WP_011018152.1 tyrosine-type recombinase/integrase -

Sequence


Protein


Download         Length: 139 a.a.        Molecular weight: 15663.32 Da        Isoelectric Point: 4.8660

>NTDB_id=21952 SPYM18_RS07730 WP_011018140.1 1483437..1483856(-) (ssbA) [Streptococcus pyogenes MGAS8232]
MINNVVLVGRMTKDAELRYTASQVAVATFTLAVNRRFKEQNGEREADFINCVIWRQSAENLANWAKKGALIGITGRIQTR
NYENQQGQRVYVTEVVADNFQMLESRNQQSGQGNSSQNDNSQPFGNSNPMDISDDDLPF

Nucleotide


Download         Length: 420 bp        

>NTDB_id=21952 SPYM18_RS07730 WP_011018140.1 1483437..1483856(-) (ssbA) [Streptococcus pyogenes MGAS8232]
ATGATTAATAACGTAGTACTAGTTGGTCGCATGACCAAGGACGCAGAGCTTCGCTATACAGCGAGTCAAGTAGCTGTAGC
TACGTTCACACTTGCGGTAAACCGCAGATTTAAAGAGCAAAACGGGGAGAGAGAAGCAGATTTCATTAACTGTGTTATCT
GGCGACAGTCTGCTGAAAATTTAGCCAACTGGGCTAAAAAAGGTGCCTTGATCGGAATTACAGGTCGTATTCAGACACGT
AACTACGAAAACCAACAAGGACAACGTGTCTATGTAACAGAAGTTGTTGCAGATAATTTCCAAATGTTGGAAAGTCGTAA
TCAACAATCTGGTCAAGGTAACTCTTCGCAAAACGATAACAGTCAACCGTTTGGCAATTCAAACCCAATGGATATTTCAG
ACGATGATCTGCCGTTTTAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

54.286

100

0.683

  ssb Latilactobacillus sakei subsp. sakei 23K

55.294

100

0.676

  ssbB/cilA Streptococcus pneumoniae TIGR4

45.324

100

0.453

  ssbB/cilA Streptococcus pneumoniae Rx1

44.604

100

0.446

  ssbB Streptococcus sobrinus strain NIDR 6715-7

44.604

100

0.446

  ssbB/cilA Streptococcus mitis NCTC 12261

44.604

100

0.446

  ssbB/cilA Streptococcus pneumoniae D39

44.604

100

0.446

  ssbB/cilA Streptococcus pneumoniae R6

44.604

100

0.446

  ssbB/cilA Streptococcus mitis SK321

44.604

100

0.446

  ssbB Bacillus subtilis subsp. subtilis str. 168

54.054

79.856

0.432

  ssbA Streptococcus mutans UA159

41.727

100

0.417

  ssb Vibrio cholerae strain A1552

31.792

100

0.396


Multiple sequence alignment