Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaR   Type   Regulator
Locus tag   CWQ22_RS08820 Genome accession   NZ_CP025027
Coordinates   1676340..1677014 (-) Length   224 a.a.
NCBI ID   WP_001238600.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain SGEHI2015-107     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1671340..1682014
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CWQ22_RS08795 (CWQ22_08795) dltC 1671956..1672195 (-) 240 WP_000351975.1 D-alanine--poly(phosphoribitol) ligase subunit DltC -
  CWQ22_RS08800 (CWQ22_08800) dltB 1672210..1673475 (-) 1266 WP_000613595.1 D-alanyl-lipoteichoic acid biosynthesis protein DltB -
  CWQ22_RS08805 (CWQ22_08805) dltA 1673472..1675007 (-) 1536 WP_017647764.1 D-alanine--poly(phosphoribitol) ligase subunit DltA -
  CWQ22_RS08810 (CWQ22_08810) - 1675020..1675142 (-) 123 WP_000806141.1 teichoic acid D-Ala incorporation-associated protein DltX -
  CWQ22_RS08815 (CWQ22_08815) dltS 1675153..1676340 (-) 1188 WP_000490535.1 two-component system sensor histidine kinase DltS -
  CWQ22_RS08820 (CWQ22_08820) ciaR 1676340..1677014 (-) 675 WP_001238600.1 two-component system response regulator DltR Regulator
  CWQ22_RS08825 (CWQ22_08825) rpmH 1677370..1677504 (-) 135 WP_000831903.1 50S ribosomal protein L34 -
  CWQ22_RS08830 (CWQ22_08830) - 1677688..1679043 (-) 1356 WP_017647765.1 YjiH family protein -
  CWQ22_RS08835 (CWQ22_08835) - 1679289..1681016 (-) 1728 WP_000429358.1 ABC transporter permease/substrate binding protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 25521.52 Da        Isoelectric Point: 5.2130

>NTDB_id=216333 CWQ22_RS08820 WP_001238600.1 1676340..1677014(-) (ciaR) [Streptococcus agalactiae strain SGEHI2015-107]
MRLLVVEDEKSIAEAIQALLADKGYSVDLVFDGDDGLEYILTGLYDLVLLDIMLPKRSGLSILKRVREAGLETPIIFLTA
KSQTYDKVNGLDLGADDYITKPFEADELLARIRLRTRQSSLIRANQLRLGNIRLNTDSHELESKESSVKLSNKEFLLMEV
FMRNAKQIIPKNQLISKVWGPSDNSEYNQLEVFISFLRKKLRFLKADIEIITTKGFGYSLEEMT

Nucleotide


Download         Length: 675 bp        

>NTDB_id=216333 CWQ22_RS08820 WP_001238600.1 1676340..1677014(-) (ciaR) [Streptococcus agalactiae strain SGEHI2015-107]
ATGAGACTTCTTGTAGTTGAGGATGAAAAAAGTATAGCAGAGGCTATTCAGGCTTTATTGGCAGATAAAGGTTATTCTGT
TGATTTAGTATTTGATGGAGATGATGGGTTAGAATACATTTTGACAGGTCTCTATGATTTAGTCTTGTTGGATATTATGT
TACCCAAACGCTCAGGATTATCTATTTTAAAAAGAGTGAGGGAAGCTGGTTTAGAAACCCCAATAATCTTTTTAACTGCA
AAATCACAGACTTATGATAAAGTTAATGGTTTAGATTTAGGGGCAGATGATTATATCACAAAACCCTTTGAAGCAGATGA
ATTGCTAGCTAGAATTAGGTTGAGAACCAGACAATCTTCTCTGATCAGAGCAAATCAATTGCGGCTTGGAAATATAAGGC
TTAACACAGATTCACATGAGCTAGAATCTAAAGAAAGTAGTGTAAAATTATCCAATAAAGAATTTCTCTTGATGGAAGTT
TTTATGCGAAATGCAAAGCAGATTATTCCTAAAAACCAGTTGATTTCTAAGGTTTGGGGACCTTCAGACAATTCAGAATA
TAACCAGTTAGAAGTATTTATTTCTTTTTTGCGAAAAAAATTGCGCTTTTTAAAAGCAGACATTGAAATAATAACCACTA
AGGGCTTTGGATATTCCTTGGAGGAGATGACATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-113)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-220)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaR Streptococcus mutans UA159

37.838

99.107

0.375
  ciaR Streptococcus pneumoniae Rx1

37.22

99.554

0.371
  ciaR Streptococcus pneumoniae D39

37.22

99.554

0.371
  ciaR Streptococcus pneumoniae R6

37.22

99.554

0.371
  ciaR Streptococcus pneumoniae TIGR4

37.22

99.554

0.371

Multiple sequence alignment