Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   BZG42_RS00790 Genome accession   NZ_CP019557
Coordinates   120644..121594 (+) Length   316 a.a.
NCBI ID   WP_155962599.1    Uniprot ID   -
Organism   Streptococcus sp. DAT741     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 115644..126594
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BZG42_RS00780 (BZG42_00755) - 119127..119495 (+) 369 WP_155972340.1 DUF1033 family protein -
  BZG42_RS00785 (BZG42_00760) - 119533..120483 (-) 951 WP_024532257.1 S66 peptidase family protein -
  BZG42_RS00790 (BZG42_00765) comYA 120644..121594 (+) 951 WP_155962599.1 competence type IV pilus ATPase ComGA Machinery gene
  BZG42_RS00795 (BZG42_00770) comYB 121515..122546 (+) 1032 WP_155995580.1 competence type IV pilus assembly protein ComGB Machinery gene
  BZG42_RS00800 (BZG42_00775) comYC 122543..122824 (+) 282 WP_024532254.1 competence type IV pilus major pilin ComGC Machinery gene
  BZG42_RS00805 (BZG42_00780) comGD 122811..123224 (+) 414 WP_155995578.1 competence type IV pilus minor pilin ComGD -
  BZG42_RS00810 (BZG42_00785) comYE 123196..123489 (+) 294 WP_155995576.1 competence type IV pilus minor pilin ComGE Machinery gene
  BZG42_RS00815 (BZG42_00790) comGF/cglF 123476..123910 (+) 435 WP_024532251.1 competence type IV pilus minor pilin ComGF Machinery gene
  BZG42_RS00820 (BZG42_00795) comGG 123888..124301 (+) 414 WP_120171207.1 competence type IV pilus minor pilin ComGG -
  BZG42_RS00825 (BZG42_00800) comYH 124306..125259 (+) 954 WP_155995574.1 class I SAM-dependent methyltransferase Machinery gene
  BZG42_RS00830 (BZG42_00805) - 125309..126496 (+) 1188 WP_024532248.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35633.60 Da        Isoelectric Point: 6.6183

>NTDB_id=216198 BZG42_RS00790 WP_155962599.1 120644..121594(+) (comYA) [Streptococcus sp. DAT741]
MIQEKARQMVEQAVLARVSDLYLVPRGESYQLYHRIMDERVFLQELNEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYN
YGSGQISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERIAREIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSTEELNNALQGIAYQRLIGGGGVVDFAKENFQNHSADQWNKQIDSLFAAGYISHRQAETEKIVFGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=216198 BZG42_RS00790 WP_155962599.1 120644..121594(+) (comYA) [Streptococcus sp. DAT741]
ATGATTCAAGAAAAAGCAAGACAGATGGTGGAGCAAGCAGTGCTTGCTAGGGTTAGCGACCTTTATTTGGTTCCGCGAGG
GGAGTCCTATCAGCTCTATCATCGGATTATGGATGAACGAGTATTTTTGCAGGAATTGAATGAAGAAGAAGTGACAGCCA
TCATCAGTCATTTCAAGTTTTTGGCTGGTTTGAATGTCGGTGAAAAGCGTCGCAGTCAGCAAGGTTCTTGTGATTATAAT
TATGGTTCAGGGCAGATCTCCCTCCGCTTGTCCACTGTTGGTGATTATCGAGGTAAGGAGAGTTTGGTGATTCGATTGCT
GTACGATAACGATAAGGAACTCAAGTTTTGGTTTGAGGCAGCAGAGCGGATTGCTAGGGAAATCAAGGGGCGAGGACTCT
ACCTTTTTTCGGGTCCGGTCGGCTCTGGCAAAACCACGCTTATGTACCATCTTGCTAGGCTGAAATTCCCAGATAAACAG
ATTTTAACGATTGAAGATCCGGTAGAAATCAAACAGGAAGATATGCTCCAACTTCAGCTCAATGAAGCGATTGGGGCAAC
GTATGACAATCTGATTAAGCTGTCTCTTCGTCATCGGCCGGATTTACTGATTATTGGGGAAATACGAGATGCAGAAACAG
CAAGGGCAGTCATTCGTGCTAGTCTGACAGGTGCAACAGTTTTTTCTACTGTCCATGCTCGCAGTATTTCAGGGGTCTAT
GCTCGGATGCTAGAGCTGGGTGTCAGTACAGAGGAGTTAAATAATGCCCTTCAAGGAATTGCCTATCAACGTTTGATTGG
GGGAGGGGGTGTTGTAGATTTTGCTAAAGAAAACTTCCAAAACCATTCTGCTGACCAGTGGAATAAACAGATTGATAGCC
TTTTTGCAGCAGGATATATCAGTCATAGACAGGCAGAGACAGAAAAAATTGTCTTTGGATCACCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

67.742

98.101

0.665
  comYA Streptococcus mutans UA159

67.524

98.418

0.665
  comYA Streptococcus mutans UA140

67.524

98.418

0.665
  comGA/cglA/cilD Streptococcus pneumoniae D39

63.782

98.734

0.63
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

63.782

98.734

0.63
  comGA/cglA/cilD Streptococcus pneumoniae R6

63.782

98.734

0.63
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

63.782

98.734

0.63
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

63.462

98.734

0.627
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

63.871

98.101

0.627
  comGA Lactococcus lactis subsp. cremoris KW2

54.019

98.418

0.532
  comGA Latilactobacillus sakei subsp. sakei 23K

42.599

87.658

0.373

Multiple sequence alignment