Detailed information NTG0216202

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: BZG42_RS00815
• Genome accession: NZ_CP019557
• Coordinates: 123476..123910 (+)
• Length: 144 a.a.
• NCBI ID: WP_024532251.1
• Uniprot ID: -
• Organism: Streptococcus sp. DAT741
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 118476..128910

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BZG42_RS00780 (BZG42_00755)	-	119127..119495 (+)	369	WP_155972340.1	DUF1033 family protein	-
BZG42_RS00785 (BZG42_00760)	-	119533..120483 (-)	951	WP_024532257.1	S66 peptidase family protein	-
BZG42_RS00790 (BZG42_00765)	comYA	120644..121594 (+)	951	WP_155962599.1	competence type IV pilus ATPase ComGA	Machinery gene
BZG42_RS00795 (BZG42_00770)	comYB	121515..122546 (+)	1032	WP_155995580.1	competence type IV pilus assembly protein ComGB	Machinery gene
BZG42_RS00800 (BZG42_00775)	comYC	122543..122824 (+)	282	WP_024532254.1	competence type IV pilus major pilin ComGC	Machinery gene
BZG42_RS00805 (BZG42_00780)	comGD	122811..123224 (+)	414	WP_155995578.1	competence type IV pilus minor pilin ComGD	-
BZG42_RS00810 (BZG42_00785)	comYE	123196..123489 (+)	294	WP_155995576.1	competence type IV pilus minor pilin ComGE	Machinery gene
BZG42_RS00815 (BZG42_00790)	comGF/cglF	123476..123910 (+)	435	WP_024532251.1	competence type IV pilus minor pilin ComGF	Machinery gene
BZG42_RS00820 (BZG42_00795)	comGG	123888..124301 (+)	414	WP_120171207.1	competence type IV pilus minor pilin ComGG	-
BZG42_RS00825 (BZG42_00800)	comYH	124306..125259 (+)	954	WP_155995574.1	class I SAM-dependent methyltransferase	Machinery gene
BZG42_RS00830 (BZG42_00805)	-	125309..126496 (+)	1188	WP_024532248.1	acetate kinase	-
BZG42_RS00835 (BZG42_00810)	-	126801..127355 (+)	555	WP_024532247.1	folate family ECF transporter S component	-
BZG42_RS00840 (BZG42_00815)	-	127454..128710 (+)	1257	WP_155972328.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16473.95 Da
• Isoelectric Point: 8.8413

>NTDB_id=216202 BZG42_RS00815 WP_024532251.1 123476..123910(+) (comGF/cglF) [Streptococcus sp. DAT741]
MLKTRAPAFTLLECLVALVVLSGSLLVFEGLSKLISHEVRYQSKVLQKDWLLFSDQLRAEWAQAALVRVENNRIYINKEG
QGLAFGKSRSDDFRKTNEKGQGYQPMLYGLQATEIVQEGRLVRMDFTFTNGEERTFIYAFEKTG

Nucleotide

• Length: 435 bp

>NTDB_id=216202 BZG42_RS00815 WP_024532251.1 123476..123910(+) (comGF/cglF) [Streptococcus sp. DAT741]
TTGCTAAAAACTAGGGCTCCAGCTTTTACTCTTTTAGAATGTTTAGTGGCTTTGGTCGTCCTGTCGGGGAGTCTCTTAGT
ATTTGAAGGATTAAGCAAATTGATTTCTCATGAAGTTCGTTACCAAAGCAAGGTGCTTCAAAAGGATTGGCTCCTTTTCT
CGGATCAGCTGCGTGCAGAATGGGCTCAGGCGGCTTTGGTTAGAGTTGAGAATAACAGAATCTACATCAATAAGGAAGGT
CAAGGTCTTGCCTTTGGAAAATCACGTTCGGATGATTTTCGGAAGACGAATGAGAAGGGGCAAGGGTATCAGCCTATGTT
ATACGGTCTTCAAGCGACGGAAATTGTTCAAGAGGGAAGACTAGTTAGAATGGATTTTACCTTTACAAATGGAGAGGAGC
GAACCTTTATCTATGCTTTTGAAAAAACAGGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (40-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus mitis NCTC 12261	53.237	96.528	0.514
comGF/cglF	Streptococcus pneumoniae Rx1	52.899	95.833	0.507
comGF/cglF	Streptococcus pneumoniae D39	52.899	95.833	0.507
comGF/cglF	Streptococcus pneumoniae R6	52.899	95.833	0.507
comGF/cglF	Streptococcus pneumoniae TIGR4	52.899	95.833	0.507
comGF/cglF	Streptococcus mitis SK321	51.799	96.528	0.5
comYF	Streptococcus mutans UA159	50.355	97.917	0.493
comYF	Streptococcus mutans UA140	49.645	97.917	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	45.775	98.611	0.451