Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   BKM67_RS00755 Genome accession   NZ_CP017667
Coordinates   121472..122422 (+) Length   316 a.a.
NCBI ID   WP_024412239.1    Uniprot ID   -
Organism   Streptococcus suis strain 1081     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 116472..127422
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM67_RS00745 (BKM67_00740) - 120034..120408 (+) 375 WP_024385120.1 DUF1033 family protein -
  BKM67_RS00750 (BKM67_00745) - 120436..121386 (-) 951 WP_105183744.1 S66 peptidase family protein -
  BKM67_RS00755 (BKM67_00750) comYA 121472..122422 (+) 951 WP_024412239.1 competence type IV pilus ATPase ComGA Machinery gene
  BKM67_RS00760 (BKM67_00755) comYB 122334..123371 (+) 1038 WP_238145568.1 competence type IV pilus assembly protein ComGB Machinery gene
  BKM67_RS00765 (BKM67_00760) comYC 123373..123654 (+) 282 WP_024385124.1 competence type IV pilus major pilin ComGC Machinery gene
  BKM67_RS00770 (BKM67_00765) comGD 123635..124042 (+) 408 WP_015646273.1 competence type IV pilus minor pilin ComGD -
  BKM67_RS00775 (BKM67_00770) comYE 124014..124307 (+) 294 WP_105178942.1 competence type IV pilus minor pilin ComGE Machinery gene
  BKM67_RS00780 (BKM67_00775) comGF/cglF 124294..124728 (+) 435 WP_105178941.1 competence type IV pilus minor pilin ComGF Machinery gene
  BKM67_RS00785 (BKM67_00780) comGG 124706..125119 (+) 414 WP_105183746.1 competence type IV pilus minor pilin ComGG -
  BKM67_RS00790 (BKM67_00785) comYH 125169..126122 (+) 954 WP_105183747.1 class I SAM-dependent methyltransferase Machinery gene
  BKM67_RS00795 (BKM67_00790) - 126172..127359 (+) 1188 WP_105183748.1 acetate kinase -

Sequence

Protein


Download         Length: 316 a.a.        Molecular weight: 35455.33 Da        Isoelectric Point: 5.6938

>NTDB_id=201336 BKM67_RS00755 WP_024412239.1 121472..122422(+) (comYA) [Streptococcus suis strain 1081]
MIQEKARKMIEEAVADRVSDIYLVPRGQGYQVYHRIMDEREFVQDLAEEEVTAMISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDVETARAVIRASLTGATVFSTVHARSISGVY
TRMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide


Download         Length: 951 bp        

>NTDB_id=201336 BKM67_RS00755 WP_024412239.1 121472..122422(+) (comYA) [Streptococcus suis strain 1081]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTTAGTGACATCTATCTGGTTCCTCGTGG
TCAGGGCTACCAAGTCTACCATCGTATCATGGACGAGCGAGAGTTTGTGCAAGACTTGGCTGAGGAGGAAGTAACAGCCA
TGATCAGCCATTTCAAGTTTTTAGCAGGTTTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGTAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTCTGGTTATCCGCCTGCT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACACTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATCGAGGATCCTGTCGAAATCAAACAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATCTAATCAAACTGTCCCTCCGTCATCGACCAGACTTGCTCATCATCGGTGAGATTCGGGATGTAGAAACCG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACAGTTCATGCAAGGTCTATTTCAGGTGTCTAT
ACCCGTATGTTAGAACTAGGTGTCAGTCCTGAGGAGTTAAATAATGCCCTTCAAGGGATTGCCTATCAACGCTTGATTGG
GGGAGGAGGTGTAGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGCC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGTTCGCCAGCGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

68.71

98.101

0.674
  comYA Streptococcus mutans UA159

67.203

98.418

0.661
  comYA Streptococcus mutans UA140

67.203

98.418

0.661
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae D39

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae R6

65.273

98.418

0.642
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

65.273

98.418

0.642
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

64.516

98.101

0.633
  comGA Lactococcus lactis subsp. cremoris KW2

53.312

100

0.535
  comGA Latilactobacillus sakei subsp. sakei 23K

41.155

87.658

0.361

Multiple sequence alignment