Detailed information NTG0201285

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: BKM66_RS00765
• Genome accession: NZ_CP017666
• Coordinates: 123402..123683 (+)
• Length: 93 a.a.
• NCBI ID: WP_024385124.1
• Uniprot ID: A0A0Z8HXH6
• Organism: Streptococcus suis strain 0061
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 118402..128683

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BKM66_RS00745 (BKM66_00740)	-	120063..120437 (+)	375	WP_024385120.1	DUF1033 family protein	-
BKM66_RS00750 (BKM66_00745)	-	120465..121415 (-)	951	WP_105183744.1	S66 peptidase family protein	-
BKM66_RS00755 (BKM66_00750)	comYA	121501..122451 (+)	951	WP_024412239.1	competence type IV pilus ATPase ComGA	Machinery gene
BKM66_RS00760 (BKM66_00755)	comYB	122363..123400 (+)	1038	WP_238145568.1	competence type IV pilus assembly protein ComGB	Machinery gene
BKM66_RS00765 (BKM66_00760)	comYC	123402..123683 (+)	282	WP_024385124.1	competence type IV pilus major pilin ComGC	Machinery gene
BKM66_RS00770 (BKM66_00765)	comGD	123664..124071 (+)	408	WP_015646273.1	competence type IV pilus minor pilin ComGD	-
BKM66_RS00775 (BKM66_00770)	comYE	124043..124336 (+)	294	WP_105178942.1	competence type IV pilus minor pilin ComGE	Machinery gene
BKM66_RS00780 (BKM66_00775)	comGF/cglF	124323..124757 (+)	435	WP_105178941.1	competence type IV pilus minor pilin ComGF	Machinery gene
BKM66_RS00785 (BKM66_00780)	comGG	124735..125148 (+)	414	WP_105183746.1	competence type IV pilus minor pilin ComGG	-
BKM66_RS00790 (BKM66_00785)	comYH	125198..126151 (+)	954	WP_105183747.1	class I SAM-dependent methyltransferase	Machinery gene
BKM66_RS00795 (BKM66_00790)	-	126201..127388 (+)	1188	WP_105183748.1	acetate kinase	-
BKM66_RS00800 (BKM66_00795)	-	127702..128253 (+)	552	WP_074391332.1	folate family ECF transporter S component	-

Sequence

Protein

• Length: 93 a.a.
• Molecular weight: 10474.44 Da
• Isoelectric Point: 6.3464

>NTDB_id=201285 BKM66_RS00765 WP_024385124.1 123402..123683(+) (comYC) [Streptococcus suis strain 0061]
MKKLIEMKVKGFTLVEMLVVLGIISLLLLLFVPNLSQQKDAIQKKGDAAVVKVVESQMELYELEYDKEATVEDLQKAGYI
TPKQAEQYATAKK

Nucleotide

• Length: 282 bp

>NTDB_id=201285 BKM66_RS00765 WP_024385124.1 123402..123683(+) (comYC) [Streptococcus suis strain 0061]
ATGAAAAAGTTAATTGAAATGAAGGTAAAAGGGTTCACTCTGGTGGAAATGTTAGTTGTTTTGGGAATTATCAGCCTGCT
CTTGCTCCTCTTTGTGCCAAATTTGAGCCAGCAGAAGGATGCTATTCAGAAGAAGGGGGATGCGGCAGTTGTTAAGGTAG
TAGAGAGTCAAATGGAGCTCTATGAATTGGAATATGATAAGGAAGCAACGGTGGAGGACTTGCAAAAGGCTGGTTATATT
ACACCAAAACAAGCGGAGCAGTATGCTACGGCGAAAAAATAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0Z8HXH6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus suis isolate S10	91.398	100	0.914
comGC/cglC	Streptococcus pneumoniae TIGR4	60.87	98.925	0.602
comGC/cglC	Streptococcus pneumoniae Rx1	60.87	98.925	0.602
comGC/cglC	Streptococcus pneumoniae D39	60.87	98.925	0.602
comGC/cglC	Streptococcus pneumoniae R6	60.87	98.925	0.602
comGC/cglC	Streptococcus mitis NCTC 12261	60.87	98.925	0.602
comGC/cglC	Streptococcus mitis SK321	60.87	98.925	0.602
comYC	Streptococcus gordonii str. Challis substr. CH1	61.798	95.699	0.591
comYC	Streptococcus mutans UA140	59.091	94.624	0.559
comYC	Streptococcus mutans UA159	59.091	94.624	0.559
comGC	Lactococcus lactis subsp. cremoris KW2	56.818	94.624	0.538
comGC	Staphylococcus aureus MW2	48.649	79.57	0.387
comGC	Staphylococcus aureus N315	48.649	79.57	0.387
comGC	Bacillus subtilis subsp. subtilis str. 168	46.667	80.645	0.376