Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   BKM66_RS00760 Genome accession   NZ_CP017666
Coordinates   122363..123400 (+) Length   345 a.a.
NCBI ID   WP_238145568.1    Uniprot ID   -
Organism   Streptococcus suis strain 0061     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 117363..128400
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM66_RS00745 (BKM66_00740) - 120063..120437 (+) 375 WP_024385120.1 DUF1033 family protein -
  BKM66_RS00750 (BKM66_00745) - 120465..121415 (-) 951 WP_105183744.1 S66 peptidase family protein -
  BKM66_RS00755 (BKM66_00750) comYA 121501..122451 (+) 951 WP_024412239.1 competence type IV pilus ATPase ComGA Machinery gene
  BKM66_RS00760 (BKM66_00755) comYB 122363..123400 (+) 1038 WP_238145568.1 competence type IV pilus assembly protein ComGB Machinery gene
  BKM66_RS00765 (BKM66_00760) comYC 123402..123683 (+) 282 WP_024385124.1 competence type IV pilus major pilin ComGC Machinery gene
  BKM66_RS00770 (BKM66_00765) comGD 123664..124071 (+) 408 WP_015646273.1 competence type IV pilus minor pilin ComGD -
  BKM66_RS00775 (BKM66_00770) comYE 124043..124336 (+) 294 WP_105178942.1 competence type IV pilus minor pilin ComGE Machinery gene
  BKM66_RS00780 (BKM66_00775) comGF/cglF 124323..124757 (+) 435 WP_105178941.1 competence type IV pilus minor pilin ComGF Machinery gene
  BKM66_RS00785 (BKM66_00780) comGG 124735..125148 (+) 414 WP_105183746.1 competence type IV pilus minor pilin ComGG -
  BKM66_RS00790 (BKM66_00785) comYH 125198..126151 (+) 954 WP_105183747.1 class I SAM-dependent methyltransferase Machinery gene
  BKM66_RS00795 (BKM66_00790) - 126201..127388 (+) 1188 WP_105183748.1 acetate kinase -
  BKM66_RS00800 (BKM66_00795) - 127702..128253 (+) 552 WP_074391332.1 folate family ECF transporter S component -

Sequence

Protein


Download         Length: 345 a.a.        Molecular weight: 39024.99 Da        Isoelectric Point: 8.8936

>NTDB_id=201284 BKM66_RS00760 WP_238145568.1 122363..123400(+) (comYB) [Streptococcus suis strain 0061]
MRKLIAFLQQDISVFGRQKQKKLPLVRQRKVIELFNNLFASGFHLGEIVDFLKRSQLLADPYTQVLSDGLLAGKPFSSLL
ADLRFSDAVVTQVALAEVHGNTSLSLSHIQSYLENVSKVRKKLIEVATYPIILLGFLLLIMLGLKNYLLPQLEEGNAATV
LINHLPTIFLSLCGLSLVAVLAGLVWFRKTNKIRVFSCLAALPFFGKLIQTYLTAYYAREWGSLIGQGLDLPQIVGLMQE
QQSQLFREIGQDLEQSLSNGQDFHEHIKTYAFFKRELSLIVEYGQVKSKLGSELTVYAAECWEDFFSRVNRAMQLIQPLV
FLFVALMVVLIYAAMLLPIYQNMEL

Nucleotide


Download         Length: 1038 bp        

>NTDB_id=201284 BKM66_RS00760 WP_238145568.1 122363..123400(+) (comYB) [Streptococcus suis strain 0061]
ATGCGCAAATTGATCGCCTTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGTTCG
CCAGCGTAAGGTCATTGAGCTTTTCAATAATCTTTTTGCTAGTGGTTTTCATTTGGGGGAGATTGTTGATTTCCTCAAAC
GCAGTCAGCTTCTGGCAGATCCCTATACCCAGGTCTTGTCAGACGGGCTGTTAGCAGGCAAACCCTTTTCAAGTTTGCTG
GCGGATTTGCGGTTTTCAGATGCGGTGGTCACACAGGTGGCTCTGGCAGAAGTTCATGGCAATACCAGCCTGAGTTTGAG
CCATATCCAGTCCTATCTGGAAAATGTCAGCAAGGTCCGTAAAAAACTGATTGAGGTGGCGACCTATCCGATTATCTTAC
TTGGTTTTCTGCTCTTGATTATGCTGGGCTTGAAAAACTATCTTCTGCCCCAGTTGGAGGAGGGCAATGCGGCTACCGTG
CTAATTAATCATCTGCCGACCATCTTTTTATCCCTCTGTGGACTTAGTTTGGTGGCGGTCTTAGCTGGTCTTGTTTGGTT
TCGCAAAACTAACAAAATCAGGGTCTTTTCCTGCTTAGCAGCTCTGCCATTTTTCGGAAAACTCATCCAAACCTATCTGA
CGGCCTATTACGCCAGGGAGTGGGGGAGTTTGATTGGGCAAGGCTTGGACCTGCCGCAGATTGTGGGTTTGATGCAGGAG
CAGCAATCGCAGCTCTTTCGGGAGATTGGGCAGGACCTGGAGCAGTCGCTTTCCAATGGTCAGGATTTTCACGAACACAT
CAAGACCTACGCCTTTTTCAAGCGGGAGCTGAGCTTGATTGTGGAGTATGGTCAGGTCAAGTCCAAGTTGGGGAGCGAGT
TGACAGTTTATGCAGCAGAGTGCTGGGAGGATTTTTTCTCTCGGGTTAATAGAGCCATGCAGCTGATTCAACCGCTGGTC
TTTCTCTTTGTGGCCTTAATGGTCGTGCTTATCTACGCAGCCATGTTGCTGCCGATTTATCAAAATATGGAGTTATAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus gordonii str. Challis substr. CH1

63.743

99.13

0.632
  comGB/cglB Streptococcus mitis NCTC 12261

61.194

97.101

0.594
  comGB/cglB Streptococcus mitis SK321

60.896

97.101

0.591
  comYB Streptococcus mutans UA140

59.184

99.42

0.588
  comYB Streptococcus mutans UA159

59.184

99.42

0.588
  comGB/cglB Streptococcus pneumoniae Rx1

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae D39

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae R6

60.299

97.101

0.586
  comGB/cglB Streptococcus pneumoniae TIGR4

60.299

97.101

0.586
  comGB Lactococcus lactis subsp. cremoris KW2

50.445

97.681

0.493

Multiple sequence alignment