Detailed information NTG0020122

Bioinformatically predicted

Overview

• Name: comYA
• Type: Machinery gene
• Locus tag: Spy49_0090
• Genome accession: CP000829
• Coordinates: 102272..103210 (+)
• Length: 312 a.a.
• NCBI ID: ACI60443.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes NZ131
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 97272..108210

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Spy49_0088	rpoC	98048..101662 (+)	3615	ACI60441.1	DNA-directed RNA polymerase beta subunit	-
Spy49_0089	-	101814..102179 (+)	366	ACI60442.1	Putative DNA binding protein	-
Spy49_0090	comYA	102272..103210 (+)	939	ACI60443.1	Putative ABC transporter subunit ComYA	Machinery gene
Spy49_0091	comYB	103305..104180 (+)	876	ACI60444.1	Putative competence protein, ABC transporter subunit	Machinery gene
Spy49_0092	comGC	104182..104508 (+)	327	ACI60445.1	Putative competence protein	Machinery gene
Spy49_0093	-	104483..104911 (+)	429	ACI60446.1	Competence protein	-
Spy49_0094	-	104868..105152 (+)	285	ACI60447.1	hypothetical protein	-
Spy49_0095	comYD	105145..105579 (+)	435	ACI60448.1	Putative competence protein	-
Spy49_0096	-	105599..105889 (+)	291	ACI60449.1	hypothetical protein	-
Spy49_0097	comYH	105987..106940 (+)	954	ACI60450.1	Adenine-specific methyltransferase	Machinery gene
Spy49_0098	ackA	106999..108195 (+)	1197	ACI60451.1	Acetate kinase	-

Sequence

Protein

• Length: 312 a.a.
• Molecular weight: 35017.21 Da
• Isoelectric Point: 8.2452

>NTDB_id=20122 Spy49_0090 ACI60443.1 102272..103210(+) (comYA) [Streptococcus pyogenes NZ131]
MVQALAKAILAKAEQVQAQDIYILPRADQYDLFLRIGDERRLVDVYQSDRMAPLVSHFKFVAGMIVGEKRRCQVGSCDYK
LSKDKQLSLRLSSVGDYRGQESLVIRLLHHQNKSVHYWFDGLTKVANQVGGRGLYLFAGPVGSGKTTLMYQLISNYHQEA
QVISIEDPVEIKNHQILQLQVNDDIGMTYDNLIKLSLRHQPDILVIGEIRDSQTARAVIRASLTGAMVFSTVHAKSISGV
YARLLELGVTKAELSNCLALIAYQRLLNGGALIDSTQNEFEYYSSSNWNQQIDQLLEAGHLNPKQAKLEKII

Nucleotide

• Length: 939 bp

>NTDB_id=20122 Spy49_0090 ACI60443.1 102272..103210(+) (comYA) [Streptococcus pyogenes NZ131]
ATGGTACAAGCATTAGCAAAAGCTATTCTAGCAAAAGCTGAACAGGTTCAGGCACAAGATATTTATATTTTGCCAAGAGC
AGATCAATATGATCTTTTTTTACGAATAGGAGATGAAAGGAGATTAGTTGATGTTTATCAGAGCGATCGGATGGCTCCTC
TTGTTAGTCACTTTAAATTCGTTGCAGGAATGATAGTTGGTGAAAAGAGACGTTGTCAGGTGGGTTCATGTGATTATAAG
CTCAGTAAAGATAAGCAGTTATCTTTGCGCTTATCTAGCGTGGGTGATTATCGCGGGCAAGAAAGCTTAGTGATTCGTCT
GCTTCATCATCAAAATAAAAGTGTACATTATTGGTTTGATGGATTGACAAAAGTAGCCAATCAGGTTGGCGGTAGAGGGT
TGTATTTATTTGCAGGACCAGTTGGGTCTGGGAAGACAACCTTGATGTACCAGCTGATTTCGAATTATCATCAAGAAGCA
CAGGTTATTAGTATAGAAGATCCTGTAGAAATTAAAAATCACCAGATTTTACAATTACAAGTGAATGATGATATTGGTAT
GACTTATGACAATTTGATCAAACTGTCTTTACGCCATCAACCAGATATTTTAGTTATTGGTGAGATTCGAGATAGTCAAA
CAGCAAGAGCCGTTATTAGGGCTAGTCTAACAGGTGCCATGGTTTTTTCAACGGTTCACGCTAAAAGTATCTCGGGTGTT
TATGCAAGATTGTTAGAACTTGGTGTAACGAAAGCAGAACTGTCTAATTGCTTAGCATTAATTGCTTACCAAAGGTTACT
TAATGGAGGAGCATTGATTGACTCTACTCAAAACGAATTTGAATATTATTCCTCATCGAACTGGAATCAACAAATTGATC
AGCTTCTTGAGGCAGGACATCTCAATCCCAAGCAAGCTAAGCTTGAAAAAATTATCTAG

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (9-267)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYA	Streptococcus mutans UA159	61.093	99.679	0.609
comYA	Streptococcus mutans UA140	61.093	99.679	0.609
comYA	Streptococcus gordonii str. Challis substr. CH1	60.129	99.679	0.599
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	60	99.359	0.596
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	58.842	99.679	0.587
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	58.199	99.679	0.58
comGA/cglA/cilD	Streptococcus pneumoniae D39	58.199	99.679	0.58
comGA/cglA/cilD	Streptococcus pneumoniae R6	58.199	99.679	0.58
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	58.199	99.679	0.58
comGA	Lactococcus lactis subsp. cremoris KW2	50.161	99.679	0.5
comGA	Latilactobacillus sakei subsp. sakei 23K	39.31	92.949	0.365