Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   Spy49_0097 Genome accession   CP000829
Coordinates   105987..106940 (+) Length   317 a.a.
NCBI ID   ACI60450.1    Uniprot ID   -
Organism   Streptococcus pyogenes NZ131     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 100987..111940
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Spy49_0089 - 101814..102179 (+) 366 ACI60442.1 Putative DNA binding protein -
  Spy49_0090 comYA 102272..103210 (+) 939 ACI60443.1 Putative ABC transporter subunit ComYA Machinery gene
  Spy49_0091 comYB 103305..104180 (+) 876 ACI60444.1 Putative competence protein, ABC transporter subunit Machinery gene
  Spy49_0092 comGC 104182..104508 (+) 327 ACI60445.1 Putative competence protein Machinery gene
  Spy49_0093 - 104483..104911 (+) 429 ACI60446.1 Competence protein -
  Spy49_0094 - 104868..105152 (+) 285 ACI60447.1 hypothetical protein -
  Spy49_0095 comYD 105145..105579 (+) 435 ACI60448.1 Putative competence protein -
  Spy49_0096 - 105599..105889 (+) 291 ACI60449.1 hypothetical protein -
  Spy49_0097 comYH 105987..106940 (+) 954 ACI60450.1 Adenine-specific methyltransferase Machinery gene
  Spy49_0098 ackA 106999..108195 (+) 1197 ACI60451.1 Acetate kinase -
  Spy49_0099 - 108381..108623 (+) 243 ACI60452.1 hypothetical protein -
  Spy49_0100 proC 108772..109542 (-) 771 ACI60453.1 Pyrroline-5-carboxylate reductase -
  Spy49_0101 pepA 109590..110657 (-) 1068 ACI60454.1 Putative glutamyl-aminopeptidase -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35995.11 Da        Isoelectric Point: 4.7205

>NTDB_id=20125 Spy49_0097 ACI60450.1 105987..106940(+) (comYH) [Streptococcus pyogenes NZ131]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDDIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDPIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN

Nucleotide


Download         Length: 954 bp        

>NTDB_id=20125 Spy49_0097 ACI60450.1 105987..106940(+) (comYH) [Streptococcus pyogenes NZ131]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGATATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACGCTACCAGATCCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(68-288)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA159

66.139

99.685

0.659
  comYH Streptococcus mutans UA140

65.823

99.685

0.656

Multiple sequence alignment