Detailed information NTG0020123

Bioinformatically predicted

Overview

• Name: comYB
• Type: Machinery gene
• Locus tag: Spy49_0091
• Genome accession: CP000829
• Coordinates: 103305..104180 (+)
• Length: 291 a.a.
• NCBI ID: ACI60444.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes NZ131
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 98305..109180

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Spy49_0089	-	101814..102179 (+)	366	ACI60442.1	Putative DNA binding protein	-
Spy49_0090	comYA	102272..103210 (+)	939	ACI60443.1	Putative ABC transporter subunit ComYA	Machinery gene
Spy49_0091	comYB	103305..104180 (+)	876	ACI60444.1	Putative competence protein, ABC transporter subunit	Machinery gene
Spy49_0092	comGC	104182..104508 (+)	327	ACI60445.1	Putative competence protein	Machinery gene
Spy49_0093	-	104483..104911 (+)	429	ACI60446.1	Competence protein	-
Spy49_0094	-	104868..105152 (+)	285	ACI60447.1	hypothetical protein	-
Spy49_0095	comYD	105145..105579 (+)	435	ACI60448.1	Putative competence protein	-
Spy49_0096	-	105599..105889 (+)	291	ACI60449.1	hypothetical protein	-
Spy49_0097	comYH	105987..106940 (+)	954	ACI60450.1	Adenine-specific methyltransferase	Machinery gene
Spy49_0098	ackA	106999..108195 (+)	1197	ACI60451.1	Acetate kinase	-
Spy49_0099	-	108381..108623 (+)	243	ACI60452.1	hypothetical protein	-

Sequence

Protein

• Length: 291 a.a.
• Molecular weight: 33665.00 Da
• Isoelectric Point: 8.5878

>NTDB_id=20123 Spy49_0091 ACI60444.1 103305..104180(+) (comYB) [Streptococcus pyogenes NZ131]
MLQLDYVLKMEESLLKGQGLADMLSGLGFSDAILTQISLADRHGNIETTLVAIQHYLNQMARIRRKTVEVITYPLILLLF
LFVMMLGLRRYLVPQLETQNQITYFLNHFPAFFIGFCSGLILLFGMVWLRWRSQSRLKLYSRLSRYPFLGKLLKQYLTSY
YAREWGTLIGQGLDLMTILDIMAIEKSSLMKELAEDIRMSLLEGQAFHIKVATYPFFKKELSLMIEYGEIKSKLGAELEI
YAQESWEQFFSQLYQVTQLIQPAIFLVVAVTIVMIYAAILLPIYQNMGGIF

Nucleotide

• Length: 876 bp

>NTDB_id=20123 Spy49_0091 ACI60444.1 103305..104180(+) (comYB) [Streptococcus pyogenes NZ131]
TTGCTTCAGCTAGATTATGTTCTTAAAATGGAAGAGTCTTTATTAAAAGGACAAGGCTTAGCAGATATGTTGTCGGGTTT
AGGTTTTTCAGATGCTATTCTTACTCAAATTAGTTTAGCTGATAGACACGGTAATATTGAAACAACATTAGTAGCGATTC
AACATTACTTGAACCAAATGGCAAGGATCAGACGAAAAACTGTTGAAGTTATCACCTATCCTCTTATTCTTTTACTTTTT
CTTTTTGTCATGATGCTAGGGTTGAGACGCTATTTAGTCCCTCAATTAGAAACTCAAAATCAGATAACTTACTTTCTTAA
CCATTTTCCTGCCTTCTTTATAGGTTTTTGCTCAGGTCTTATTTTGTTGTTCGGGATGGTATGGCTACGATGGCGATCTC
AAAGCCGCTTGAAACTCTATAGTCGGCTAAGCCGTTATCCTTTTTTAGGTAAACTGTTAAAACAATACTTAACTAGTTAT
TATGCTAGAGAATGGGGTACGTTAATAGGTCAAGGTCTTGATTTGATGACTATTTTAGACATTATGGCCATTGAGAAATC
CTCACTAATGAAAGAATTAGCTGAGGACATCAGAATGAGTCTGCTTGAAGGGCAAGCCTTTCACATTAAAGTAGCTACCT
ACCCTTTTTTTAAAAAAGAATTAAGTTTAATGATTGAATACGGTGAAATCAAATCGAAACTGGGGGCTGAGTTGGAAATC
TATGCCCAGGAAAGCTGGGAACAATTTTTTAGTCAGCTTTATCAAGTGACACAACTTATTCAACCAGCTATTTTTTTAGT
AGTTGCTGTGACAATCGTCATGATTTATGCGGCAATCCTATTACCAATTTACCAAAATATGGGAGGTATTTTTTAA

Domains

Predicted by InterproScan.

• Type II secretion system (T2SS), protein F (T2SSF) (162-282)

• Type II secretion system (T2SS), protein F (T2SSF) (8-94)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYB	Streptococcus mutans UA140	54.965	96.907	0.533
comYB	Streptococcus mutans UA159	54.965	96.907	0.533
comYB	Streptococcus gordonii str. Challis substr. CH1	49.477	98.625	0.488
comGB/cglB	Streptococcus mitis NCTC 12261	47.586	99.656	0.474
comGB/cglB	Streptococcus mitis SK321	47.735	98.625	0.471
comGB/cglB	Streptococcus pneumoniae Rx1	45.296	98.625	0.447
comGB/cglB	Streptococcus pneumoniae D39	45.296	98.625	0.447
comGB/cglB	Streptococcus pneumoniae R6	45.296	98.625	0.447
comGB/cglB	Streptococcus pneumoniae TIGR4	45.296	98.625	0.447
comGB	Lactococcus lactis subsp. cremoris KW2	41.176	99.313	0.409