Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   A2G56_RS06520 Genome accession   NZ_CP014835
Coordinates   1448871..1449824 (-) Length   317 a.a.
NCBI ID   WP_062710638.1    Uniprot ID   -
Organism   Streptococcus halotolerans strain HTS9     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1443871..1454824
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2G56_RS06480 - 1443904..1445094 (-) 1191 WP_062710613.1 acetate kinase -
  A2G56_RS06485 comYH 1445155..1446108 (-) 954 WP_062710617.1 class I SAM-dependent methyltransferase Machinery gene
  A2G56_RS06490 comGG 1446151..1446558 (-) 408 WP_172793791.1 competence type IV pilus minor pilin ComGG -
  A2G56_RS06495 comYF 1446542..1446979 (-) 438 WP_062710624.1 competence type IV pilus minor pilin ComGF Machinery gene
  A2G56_RS06500 comGE 1446957..1447256 (-) 300 WP_062710628.1 competence type IV pilus minor pilin ComGE -
  A2G56_RS06505 comGD 1447228..1447650 (-) 423 WP_335339155.1 competence type IV pilus minor pilin ComGD -
  A2G56_RS06510 comYC 1447625..1447858 (-) 234 WP_237334442.1 competence type IV pilus major pilin ComGC Machinery gene
  A2G56_RS06515 comYB 1447919..1448977 (-) 1059 WP_082785120.1 competence type IV pilus assembly protein ComGB Machinery gene
  A2G56_RS06520 comYA 1448871..1449824 (-) 954 WP_062710638.1 competence type IV pilus ATPase ComGA Machinery gene
  A2G56_RS06525 - 1450032..1450412 (-) 381 WP_062710641.1 DUF1033 family protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35956.99 Da        Isoelectric Point: 5.6488

>NTDB_id=174488 A2G56_RS06520 WP_062710638.1 1448871..1449824(-) (comYA) [Streptococcus halotolerans strain HTS9]
MVQDLAKEMIAQAVECEAQDIYIIPRKDDYDVLMRIGDERRFIGTYGYDRMASLISHFKFVAGMTVGEKRRSQLGSCDYD
FGNDELVSLRLSTVGDYRGHESLVIRLLYDGRRHLNYWFNGMQEMMATIDSRGLYLFSGPTGSGKTTLMYQLLQEKFSDK
QIISIEDPVEIKDDRILQLQLNEDINMTYNSLIKLSLRHRPDVLVIGEIRDKETARAAIRASLTGTIVFATIHAKSISGV
YHRLIELGVSEDEVKNSLAGICYQRLIGGGGLIDVAKDNFKDHVSSQWNQQLVELFKSGHLSEEQIQIESINYPKAG

Nucleotide


Download         Length: 954 bp        

>NTDB_id=174488 A2G56_RS06520 WP_062710638.1 1448871..1449824(-) (comYA) [Streptococcus halotolerans strain HTS9]
ATGGTTCAAGATTTAGCCAAAGAAATGATTGCTCAGGCAGTTGAATGTGAAGCTCAGGATATTTATATCATTCCCCGTAA
AGATGACTATGATGTGCTTATGCGAATTGGCGATGAAAGGAGATTTATCGGAACTTATGGCTATGATCGTATGGCTAGTC
TTATTAGTCACTTTAAATTTGTGGCAGGAATGACTGTCGGCGAAAAGCGTAGAAGTCAATTAGGTTCTTGTGATTATGAT
TTTGGTAACGATGAACTGGTTTCATTGCGGTTATCTACTGTTGGAGATTACCGAGGTCACGAGAGTTTAGTTATTCGCTT
GCTATATGATGGACGTCGTCATCTGAACTATTGGTTCAATGGTATGCAAGAAATGATGGCGACAATAGATTCCAGAGGAC
TCTATCTTTTTTCGGGACCTACTGGGAGTGGCAAGACAACTCTTATGTATCAACTTCTTCAAGAAAAGTTTAGCGATAAG
CAGATTATTTCGATTGAAGATCCTGTTGAAATTAAAGATGACAGGATTTTGCAACTACAGCTTAACGAAGACATTAACAT
GACTTATAACAGCTTGATTAAGTTATCCCTGAGGCATCGACCAGATGTTCTTGTCATTGGTGAAATCCGTGATAAAGAGA
CTGCACGTGCTGCAATACGTGCTAGTTTGACAGGAACCATTGTCTTTGCCACCATTCATGCTAAGAGTATTTCAGGGGTT
TATCATCGCTTAATTGAGCTGGGTGTTTCAGAGGATGAAGTAAAAAATAGTTTAGCAGGTATCTGCTATCAACGGTTAAT
AGGAGGAGGCGGATTGATTGATGTGGCAAAGGATAATTTTAAAGATCATGTTTCTAGCCAATGGAACCAGCAGTTGGTTG
AGCTTTTTAAATCAGGACATCTCTCTGAAGAACAAATCCAAATCGAGAGTATTAACTACCCAAAAGCAGGTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA140

64.952

98.107

0.637
  comYA Streptococcus mutans UA159

64.952

98.107

0.637
  comYA Streptococcus gordonii str. Challis substr. CH1

63.924

99.685

0.637
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.701

98.107

0.615
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.022

98.738

0.603
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

60.383

98.738

0.596
  comGA/cglA/cilD Streptococcus pneumoniae D39

60.383

98.738

0.596
  comGA/cglA/cilD Streptococcus pneumoniae R6

60.383

98.738

0.596
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

60.383

98.738

0.596
  comGA Lactococcus lactis subsp. cremoris KW2

48.896

100

0.489

Multiple sequence alignment