Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   A0O21_RS10360 Genome accession   NZ_CP014699
Coordinates   2208267..2209208 (+) Length   313 a.a.
NCBI ID   WP_067064906.1    Uniprot ID   A0A172QA65
Organism   Streptococcus pantholopis strain TA 26     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2203267..2214208
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS10350 (A0O21_10350) rpoC 2203950..2207594 (+) 3645 WP_067064901.1 DNA-directed RNA polymerase subunit beta' -
  A0O21_RS10355 (A0O21_10355) - 2207837..2208184 (+) 348 WP_067064904.1 DUF1033 family protein -
  A0O21_RS10360 (A0O21_10360) comYA 2208267..2209208 (+) 942 WP_067064906.1 competence type IV pilus ATPase ComGA Machinery gene
  A0O21_RS10365 (A0O21_10365) comYB 2209090..2210175 (+) 1086 WP_418346445.1 competence type IV pilus assembly protein ComGB Machinery gene
  A0O21_RS10370 (A0O21_10370) comYF 2210197..2210631 (+) 435 WP_067065306.1 competence type IV pilus minor pilin ComGF Machinery gene
  A0O21_RS10375 (A0O21_10375) comGG 2210660..2210986 (+) 327 WP_227806873.1 competence type IV pilus minor pilin ComGG -
  A0O21_RS10380 (A0O21_10380) comYH 2211205..2212161 (+) 957 WP_067064916.1 class I SAM-dependent methyltransferase Machinery gene
  A0O21_RS10385 (A0O21_10385) - 2212213..2213406 (+) 1194 WP_067064918.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35403.60 Da        Isoelectric Point: 6.5070

>NTDB_id=173383 A0O21_RS10360 WP_067064906.1 2208267..2209208(+) (comYA) [Streptococcus pantholopis strain TA 26]
MVQDLAKIIIKEAVAANAQDIYMIPKGNSYGLYLRVGVERQQMDGFESYPITSLISHFKFVAGMNVGEKRRSQLGACDYA
FAADQTVSLRLSSVGDYRGRESLVIRLLYSGIYHLRYWFDTVEHLQENIGGRGLYLFSGPVGSGKTTLMYQLATEKYFNK
QIITIEDPVEIKEEAMLQLQLNESIGMTYDNLIKLSLRHRPDILIIGEIRDKKTARAVIRASLTGIIVFSTVHAKSISGV
YARLQELGISREELNNSLQLIVYQRLIGGGGMIDFADKNFQEHIPDKWNQQIDELAEGGYITEEEAKYEKIKT

Nucleotide


Download         Length: 942 bp        

>NTDB_id=173383 A0O21_RS10360 WP_067064906.1 2208267..2209208(+) (comYA) [Streptococcus pantholopis strain TA 26]
ATGGTTCAGGATTTAGCAAAAATAATCATTAAAGAAGCTGTAGCAGCTAATGCTCAAGATATTTACATGATTCCCAAAGG
AAACAGTTACGGACTGTACCTGCGTGTGGGTGTTGAAAGACAGCAGATGGACGGTTTTGAATCTTACCCTATAACGAGTC
TTATTAGCCACTTTAAATTTGTTGCCGGAATGAATGTCGGTGAGAAGCGCCGCAGTCAGCTGGGAGCTTGTGATTATGCG
TTTGCGGCAGATCAAACTGTTTCACTGCGTTTATCAAGTGTTGGTGATTACCGAGGCCGTGAAAGTTTAGTTATCCGTCT
GCTGTATTCGGGGATTTACCACCTTAGATACTGGTTTGATACTGTTGAGCATCTGCAGGAAAATATCGGCGGCCGCGGCC
TCTATCTTTTTTCAGGGCCGGTTGGTTCCGGCAAGACAACTCTTATGTATCAATTAGCAACTGAAAAATATTTCAATAAG
CAGATTATTACGATTGAAGATCCTGTTGAGATCAAAGAAGAAGCAATGTTACAGCTCCAGCTTAATGAAAGCATCGGCAT
GACTTATGATAACCTCATCAAACTCTCGCTCCGCCACCGTCCGGATATCCTCATTATTGGAGAAATTCGGGATAAGAAAA
CGGCTCGTGCCGTTATACGGGCCAGTCTAACTGGTATTATCGTCTTTTCCACAGTTCATGCTAAAAGTATTTCCGGTGTC
TATGCCCGCCTGCAGGAACTGGGAATCAGCCGAGAAGAGTTAAATAACAGTTTGCAGCTAATCGTTTATCAGCGATTAAT
CGGAGGGGGTGGAATGATTGATTTTGCTGACAAAAATTTCCAAGAACATATTCCAGACAAGTGGAATCAGCAGATTGACG
AGCTTGCTGAAGGCGGTTATATCACCGAAGAAGAAGCGAAATACGAAAAAATTAAAACTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A172QA65

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

68.269

99.681

0.681
  comYA Streptococcus mutans UA140

68.269

99.681

0.681
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

66.559

99.361

0.661
  comYA Streptococcus gordonii str. Challis substr. CH1

62.939

100

0.629
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.179

99.681

0.62
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.415

99.361

0.61
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.415

99.361

0.61
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.415

99.361

0.61
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.415

99.361

0.61
  comGA Lactococcus lactis subsp. cremoris KW2

53.055

99.361

0.527
  comGA Latilactobacillus sakei subsp. sakei 23K

42.857

84.984

0.364

Multiple sequence alignment