Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   A0O21_RS10365 Genome accession   NZ_CP014699
Coordinates   2209090..2210175 (+) Length   361 a.a.
NCBI ID   WP_418346445.1    Uniprot ID   -
Organism   Streptococcus pantholopis strain TA 26     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 2204090..2215175
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A0O21_RS10355 (A0O21_10355) - 2207837..2208184 (+) 348 WP_067064904.1 DUF1033 family protein -
  A0O21_RS10360 (A0O21_10360) comYA 2208267..2209208 (+) 942 WP_067064906.1 competence type IV pilus ATPase ComGA Machinery gene
  A0O21_RS10365 (A0O21_10365) comYB 2209090..2210175 (+) 1086 WP_418346445.1 competence type IV pilus assembly protein ComGB Machinery gene
  A0O21_RS10370 (A0O21_10370) comYF 2210197..2210631 (+) 435 WP_067065306.1 competence type IV pilus minor pilin ComGF Machinery gene
  A0O21_RS10375 (A0O21_10375) comGG 2210660..2210986 (+) 327 WP_227806873.1 competence type IV pilus minor pilin ComGG -
  A0O21_RS10380 (A0O21_10380) comYH 2211205..2212161 (+) 957 WP_067064916.1 class I SAM-dependent methyltransferase Machinery gene
  A0O21_RS10385 (A0O21_10385) - 2212213..2213406 (+) 1194 WP_067064918.1 acetate kinase -
  A0O21_RS10390 (A0O21_10390) proC 2213581..2214351 (-) 771 WP_067064920.1 pyrroline-5-carboxylate reductase -

Sequence

Protein


Download         Length: 361 a.a.        Molecular weight: 41262.21 Da        Isoelectric Point: 10.1589

>NTDB_id=173384 A0O21_RS10365 WP_418346445.1 2209090..2210175(+) (comYB) [Streptococcus pantholopis strain TA 26]
MLTKISKNIFQTSGISRLTSLLKAVISPKKKRNTKKLKLKEQRKIVQLFNNLFDSGFSLTEMVVFLKRSQLLADKHTDKM
HSVLLNGQGLAEMMAVLGFSDAVFTQLTLAEIHGNTKRSLHKIESYLESLLLVRRKLIETGTYPLLLLAFLVILMFSLKN
YLLPQLEGVNFASQVILHFPSLLLLLLSILLVLGSALYFFAKRLPRITIVSWGSRLPWLGDYLRLYLTAYYAREWGNLIG
QGIELAQIVQIMQKQKAQLFRELGHHMGEGLLSGEEFHNKVLEYPFFCKELGLIIEYGEIKAKLGKELEIYAQETWETFF
NRLIKATQLIQPLVFIAVALMIVMIYAAMLLPMYQNIGGNF

Nucleotide


Download         Length: 1086 bp        

>NTDB_id=173384 A0O21_RS10365 WP_418346445.1 2209090..2210175(+) (comYB) [Streptococcus pantholopis strain TA 26]
TTGCTGACAAAAATTTCCAAGAACATATTCCAGACAAGTGGAATCAGCAGATTGACGAGCTTGCTGAAGGCGGTTATATC
ACCGAAGAAGAAGCGAAATACGAAAAAATTAAAACTTAAAGAACAAAGAAAGATTGTCCAATTATTTAATAATCTTTTTG
ACAGCGGTTTTAGTCTAACTGAAATGGTTGTCTTTCTTAAGCGCAGTCAGCTTTTGGCTGATAAGCATACTGATAAAATG
CATAGCGTTTTGCTAAACGGGCAGGGACTAGCAGAAATGATGGCAGTATTAGGATTCTCTGATGCTGTTTTCACCCAGCT
TACTTTGGCAGAGATTCACGGAAACACGAAAAGAAGTCTTCATAAAATAGAGTCTTATTTAGAGAGTCTTCTATTGGTTA
GACGAAAGCTGATAGAGACTGGGACTTATCCGCTGCTGCTTCTGGCATTTTTAGTAATCTTGATGTTTAGTCTAAAAAAC
TATTTGCTGCCTCAATTGGAAGGAGTAAATTTTGCCAGTCAGGTCATTCTGCATTTCCCATCCTTGTTGCTGCTCTTGCT
GTCGATCTTACTGGTGCTTGGTTCAGCTTTATATTTCTTTGCTAAACGGTTGCCGCGGATAACTATTGTTTCTTGGGGAA
GTCGTTTACCTTGGCTGGGGGATTATCTTCGTCTGTATCTGACCGCTTATTATGCGCGTGAGTGGGGGAATCTAATCGGT
CAGGGGATAGAATTAGCACAAATTGTGCAAATTATGCAAAAACAAAAAGCACAACTGTTTCGTGAATTAGGCCACCATAT
GGGAGAAGGCCTCCTTTCTGGAGAAGAGTTTCATAACAAAGTTTTGGAATATCCTTTCTTTTGTAAAGAATTGGGCCTGA
TAATTGAATACGGTGAGATCAAGGCTAAATTAGGCAAAGAATTAGAGATTTACGCTCAGGAAACTTGGGAAACATTCTTC
AATCGGCTTATAAAGGCAACACAACTGATTCAGCCTCTTGTTTTTATTGCTGTTGCCTTGATGATTGTGATGATTTACGC
AGCGATGCTGCTGCCAATGTATCAAAATATAGGAGGAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(232-352)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

62.342

87.535

0.546
  comYB Streptococcus mutans UA159

62.342

87.535

0.546
  comYB Streptococcus gordonii str. Challis substr. CH1

56.176

94.183

0.529
  comGB/cglB Streptococcus mitis NCTC 12261

53.517

90.582

0.485
  comGB/cglB Streptococcus mitis SK321

53.211

90.582

0.482
  comGB/cglB Streptococcus pneumoniae Rx1

52.905

90.582

0.479
  comGB/cglB Streptococcus pneumoniae D39

52.905

90.582

0.479
  comGB/cglB Streptococcus pneumoniae R6

52.905

90.582

0.479
  comGB/cglB Streptococcus pneumoniae TIGR4

52.905

90.582

0.479
  comGB Lactococcus lactis subsp. cremoris KW2

46.769

90.028

0.421

Multiple sequence alignment