Detailed information NTG0173386

Bioinformatically predicted

Overview

• Name: comYH
• Type: Machinery gene
• Locus tag: A0O21_RS10380
• Genome accession: NZ_CP014699
• Coordinates: 2211205..2212161 (+)
• Length: 318 a.a.
• NCBI ID: WP_067064916.1
• Uniprot ID: A0A172QA56
• Organism: Streptococcus pantholopis strain TA 26
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2206205..2217161

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A0O21_RS10355 (A0O21_10355)	-	2207837..2208184 (+)	348	WP_067064904.1	DUF1033 family protein	-
A0O21_RS10360 (A0O21_10360)	comYA	2208267..2209208 (+)	942	WP_067064906.1	competence type IV pilus ATPase ComGA	Machinery gene
A0O21_RS10365 (A0O21_10365)	comYB	2209090..2210175 (+)	1086	WP_418346445.1	competence type IV pilus assembly protein ComGB	Machinery gene
A0O21_RS10370 (A0O21_10370)	comYF	2210197..2210631 (+)	435	WP_067065306.1	competence type IV pilus minor pilin ComGF	Machinery gene
A0O21_RS10375 (A0O21_10375)	comGG	2210660..2210986 (+)	327	WP_227806873.1	competence type IV pilus minor pilin ComGG	-
A0O21_RS10380 (A0O21_10380)	comYH	2211205..2212161 (+)	957	WP_067064916.1	class I SAM-dependent methyltransferase	Machinery gene
A0O21_RS10385 (A0O21_10385)	-	2212213..2213406 (+)	1194	WP_067064918.1	acetate kinase	-
A0O21_RS10390 (A0O21_10390)	proC	2213581..2214351 (-)	771	WP_067064920.1	pyrroline-5-carboxylate reductase	-
A0O21_RS10395 (A0O21_10395)	pepA	2214614..2215678 (-)	1065	WP_067064923.1	glutamyl aminopeptidase	-
A0O21_RS10400 (A0O21_10400)	-	2215737..2216027 (+)	291	WP_067065307.1	DUF4651 domain-containing protein	-
A0O21_RS10405 (A0O21_10405)	ytpR	2216079..2216705 (+)	627	WP_067064926.1	YtpR family tRNA-binding protein	-

Sequence

Protein

• Length: 318 a.a.
• Molecular weight: 36342.38 Da
• Isoelectric Point: 4.5624

>NTDB_id=173386 A0O21_RS10380 WP_067064916.1 2211205..2212161(+) (comYH) [Streptococcus pantholopis strain TA 26]
MNFEKIESAYELVLENIQIIENHIKTNLYDALIEQNAFYLGDDSENQQVNLNNGKLHELRLTQEEWRRVFQFIFIKAAQT
EQLQANHQLTPDTIGFIFLFLIEHLAEADKLDILEIGSGTGNLAATLLNNSQKQLDYLGIEVDDLLIDLSASTAEVMNLS
ARFLQEDAVRPQILRASDIIISDLPVGFYPNDEIAKRYQVASHKEHTYAHHLLMEQSLKYLKKGGFALFLAPNDLLTSSQ
SDLLKNWLKDYADIIAVLTLPESIFGKPAYAKSIFVLRKQADCKVETFLYPFSSLQDGAVLDDFIENFQKWKIDNMHL

Nucleotide

• Length: 957 bp

>NTDB_id=173386 A0O21_RS10380 WP_067064916.1 2211205..2212161(+) (comYH) [Streptococcus pantholopis strain TA 26]
ATGAACTTTGAAAAAATTGAAAGTGCCTATGAGTTGGTTTTAGAAAATATTCAAATTATCGAAAATCACATAAAAACAAA
TCTCTATGATGCCTTAATTGAACAAAATGCCTTTTATCTAGGTGACGATAGTGAGAATCAGCAGGTCAATTTAAATAATG
GAAAATTACACGAGCTGAGATTAACACAAGAAGAGTGGCGCCGTGTTTTTCAGTTTATCTTTATCAAAGCAGCTCAAACT
GAACAGCTTCAGGCTAATCATCAGCTGACACCTGATACAATCGGTTTTATCTTTTTGTTTTTGATTGAGCATCTGGCCGA
AGCAGATAAACTGGATATTCTGGAAATTGGCAGCGGGACAGGCAATCTGGCAGCCACTTTGCTGAATAATAGTCAAAAAC
AGTTGGACTATCTGGGGATAGAGGTTGATGACCTACTAATTGATTTGTCGGCCAGCACTGCTGAAGTTATGAACCTGTCT
GCTCGATTCTTGCAAGAAGATGCGGTTCGCCCGCAGATTTTGAGAGCAAGTGATATTATTATCAGCGATCTGCCTGTCGG
TTTTTACCCTAACGATGAGATTGCTAAGCGCTATCAAGTTGCCAGTCATAAAGAGCATACTTATGCACACCATTTGTTGA
TGGAGCAGTCTTTGAAATATCTGAAAAAAGGAGGTTTTGCTCTTTTTTTAGCACCGAACGATCTGCTTACCAGCAGTCAG
AGCGATTTGCTTAAGAACTGGCTGAAAGATTATGCTGATATCATCGCTGTCCTTACGTTACCGGAGTCTATTTTTGGGAA
ACCCGCTTATGCCAAGTCTATTTTTGTTTTGCGAAAGCAAGCTGACTGTAAAGTGGAAACTTTTCTTTACCCCTTCTCAA
GTCTGCAGGATGGAGCTGTTCTTGATGACTTTATTGAGAATTTTCAAAAATGGAAAATTGATAATATGCATTTATGA

Domains

Predicted by InterproScan.

• Methyltransferase small domain (MTS) (100-186)

3D structure

• AlphaFold DB: A0A172QA56

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYH	Streptococcus mutans UA159	64.557	99.371	0.642
comYH	Streptococcus mutans UA140	64.241	99.371	0.638