Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   MGAS11027_RS00595 Genome accession   NZ_CP013838
Coordinates   97803..98129 (+) Length   108 a.a.
NCBI ID   WP_063510176.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS11027     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 92803..103129
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS11027_RS00580 (MGAS11027_0121) - 95435..95800 (+) 366 WP_002986560.1 DUF1033 family protein -
  MGAS11027_RS00585 (MGAS11027_0122) comYA 95893..96831 (+) 939 WP_023612548.1 competence type IV pilus ATPase ComGA Machinery gene
  MGAS11027_RS00590 (MGAS11027_0123) comYB 96767..97801 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  MGAS11027_RS00595 (MGAS11027_0124) comYC 97803..98129 (+) 327 WP_063510176.1 competence type IV pilus major pilin ComGC Machinery gene
  MGAS11027_RS00600 (MGAS11027_0125) comGD 98104..98532 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  MGAS11027_RS00605 (MGAS11027_0126) comGE 98489..98773 (+) 285 WP_063510177.1 competence type IV pilus minor pilin ComGE -
  MGAS11027_RS00610 (MGAS11027_0127) comYF 98766..99200 (+) 435 WP_063510178.1 competence type IV pilus minor pilin ComGF Machinery gene
  MGAS11027_RS00615 (MGAS11027_0128) comGG 99184..99510 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  MGAS11027_RS00620 (MGAS11027_0129) comYH 99608..100561 (+) 954 WP_063510179.1 class I SAM-dependent methyltransferase Machinery gene
  MGAS11027_RS00625 (MGAS11027_0130) - 100620..101816 (+) 1197 WP_063510180.1 acetate kinase -
  MGAS11027_RS00630 (MGAS11027_0131) - 102003..102311 (+) 309 WP_011284425.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12343.29 Da        Isoelectric Point: 9.3497

>NTDB_id=164993 MGAS11027_RS00595 WP_063510176.1 97803..98129(+) (comYC) [Streptococcus pyogenes strain MGAS11027]
MINQWNNLRHKKLEGFTLLEMLLVILVISVLMLLLVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYDKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=164993 MGAS11027_RS00595 WP_063510176.1 97803..98129(+) (comYC) [Streptococcus pyogenes strain MGAS11027]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAGAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
TATCAGTGTTTTGATGCTATTATTGGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATGACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(14-35)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

54.286

97.222

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

54.902

94.444

0.519
  comGC/cglC Streptococcus mitis SK321

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae TIGR4

58.696

85.185

0.5
  comGC/cglC Streptococcus pneumoniae Rx1

58.696

85.185

0.5
  comGC/cglC Streptococcus pneumoniae D39

58.696

85.185

0.5
  comGC/cglC Streptococcus mitis NCTC 12261

58.696

85.185

0.5
  comGC/cglC Streptococcus pneumoniae R6

58.696

85.185

0.5
  comYC Streptococcus mutans UA140

54.167

88.889

0.481
  comYC Streptococcus mutans UA159

54.167

88.889

0.481
  comYC Streptococcus suis isolate S10

56.79

75

0.426

Multiple sequence alignment