Detailed information NTG0164994

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: MGAS11027_RS00610
• Genome accession: NZ_CP013838
• Coordinates: 98766..99200 (+)
• Length: 144 a.a.
• NCBI ID: WP_063510178.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain MGAS11027
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 93766..104200

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
MGAS11027_RS00580 (MGAS11027_0121)	-	95435..95800 (+)	366	WP_002986560.1	DUF1033 family protein	-
MGAS11027_RS00585 (MGAS11027_0122)	comYA	95893..96831 (+)	939	WP_023612548.1	competence type IV pilus ATPase ComGA	Machinery gene
MGAS11027_RS00590 (MGAS11027_0123)	comYB	96767..97801 (+)	1035	WP_011054115.1	competence type IV pilus assembly protein ComGB	Machinery gene
MGAS11027_RS00595 (MGAS11027_0124)	comYC	97803..98129 (+)	327	WP_063510176.1	competence type IV pilus major pilin ComGC	Machinery gene
MGAS11027_RS00600 (MGAS11027_0125)	comGD	98104..98532 (+)	429	WP_002986548.1	competence type IV pilus minor pilin ComGD	-
MGAS11027_RS00605 (MGAS11027_0126)	comGE	98489..98773 (+)	285	WP_063510177.1	competence type IV pilus minor pilin ComGE	-
MGAS11027_RS00610 (MGAS11027_0127)	comYF	98766..99200 (+)	435	WP_063510178.1	competence type IV pilus minor pilin ComGF	Machinery gene
MGAS11027_RS00615 (MGAS11027_0128)	comGG	99184..99510 (+)	327	WP_002992739.1	competence type IV pilus minor pilin ComGG	-
MGAS11027_RS00620 (MGAS11027_0129)	comYH	99608..100561 (+)	954	WP_063510179.1	class I SAM-dependent methyltransferase	Machinery gene
MGAS11027_RS00625 (MGAS11027_0130)	-	100620..101816 (+)	1197	WP_063510180.1	acetate kinase	-
MGAS11027_RS00630 (MGAS11027_0131)	-	102003..102311 (+)	309	WP_011284425.1	hypothetical protein	-
MGAS11027_RS00635 (MGAS11027_0132)	proC	102394..103164 (-)	771	WP_011284426.1	pyrroline-5-carboxylate reductase	-

Sequence

Protein

• Length: 144 a.a.
• Molecular weight: 16504.09 Da
• Isoelectric Point: 10.2532

>NTDB_id=164994 MGAS11027_RS00610 WP_063510178.1 98766..99200(+) (comYF) [Streptococcus pyogenes strain MGAS11027]
MSKQLSNIKAFTLLEALIALLVISGSLLVYQGLTQTLLKRSHYLARHDQDNWLLFSHQLREELSGASFYKVADNKLYVEK
GKKVLAFGQFKSHDFRKSASNGKGYQPMLFGISRSHIHIGQSQICITLKWKSGLERTFYYAFQD

Nucleotide

• Length: 435 bp

>NTDB_id=164994 MGAS11027_RS00610 WP_063510178.1 98766..99200(+) (comYF) [Streptococcus pyogenes strain MGAS11027]
TTGAGTAAACAATTAAGTAACATAAAAGCTTTTACCCTTCTAGAGGCGTTAATAGCCTTACTCGTGATATCAGGGTCTTT
ATTGGTTTATCAAGGTTTGACCCAAACCCTCCTTAAACGTAGCCATTATCTAGCCCGTCATGATCAAGACAATTGGCTCT
TATTTTCTCATCAATTGCGAGAGGAGTTAAGTGGAGCAAGTTTTTACAAAGTAGCTGATAATAAACTATACGTTGAAAAA
GGAAAGAAAGTACTAGCTTTTGGCCAATTTAAAAGTCATGATTTCCGAAAATCAGCTAGTAATGGAAAAGGGTATCAACC
CATGTTATTTGGAATATCACGTAGTCATATTCACATAGGGCAGTCACAGATTTGCATTACTTTAAAGTGGAAAAGTGGGT
TAGAAAGGACTTTTTATTATGCCTTTCAAGACTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (41-135)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	51.079	96.528	0.493
comYF	Streptococcus mutans UA159	50.36	96.528	0.486
comGF	Lactococcus lactis subsp. cremoris KW2	45.985	95.139	0.437
comGF/cglF	Streptococcus mitis NCTC 12261	44.03	93.056	0.41
comGF/cglF	Streptococcus pneumoniae Rx1	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae D39	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae R6	43.609	92.361	0.403
comGF/cglF	Streptococcus pneumoniae TIGR4	43.609	92.361	0.403
comGF/cglF	Streptococcus mitis SK321	42.857	92.361	0.396