Detailed information
Bioinformatically predicted
Overview
| Name | comYH | Type | Machinery gene |
| Locus tag | MGAS11027_RS00620 | Genome accession | NZ_CP013838 |
| Coordinates | 99608..100561 (+) | Length | 317 a.a. |
| NCBI ID | WP_063510179.1 | Uniprot ID | - |
| Organism | Streptococcus pyogenes strain MGAS11027 | ||
| Function | dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake |
||
Genomic Context
Location: 94608..105561
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| MGAS11027_RS00580 (MGAS11027_0121) | - | 95435..95800 (+) | 366 | WP_002986560.1 | DUF1033 family protein | - |
| MGAS11027_RS00585 (MGAS11027_0122) | comYA | 95893..96831 (+) | 939 | WP_023612548.1 | competence type IV pilus ATPase ComGA | Machinery gene |
| MGAS11027_RS00590 (MGAS11027_0123) | comYB | 96767..97801 (+) | 1035 | WP_011054115.1 | competence type IV pilus assembly protein ComGB | Machinery gene |
| MGAS11027_RS00595 (MGAS11027_0124) | comYC | 97803..98129 (+) | 327 | WP_063510176.1 | competence type IV pilus major pilin ComGC | Machinery gene |
| MGAS11027_RS00600 (MGAS11027_0125) | comGD | 98104..98532 (+) | 429 | WP_002986548.1 | competence type IV pilus minor pilin ComGD | - |
| MGAS11027_RS00605 (MGAS11027_0126) | comGE | 98489..98773 (+) | 285 | WP_063510177.1 | competence type IV pilus minor pilin ComGE | - |
| MGAS11027_RS00610 (MGAS11027_0127) | comYF | 98766..99200 (+) | 435 | WP_063510178.1 | competence type IV pilus minor pilin ComGF | Machinery gene |
| MGAS11027_RS00615 (MGAS11027_0128) | comGG | 99184..99510 (+) | 327 | WP_002992739.1 | competence type IV pilus minor pilin ComGG | - |
| MGAS11027_RS00620 (MGAS11027_0129) | comYH | 99608..100561 (+) | 954 | WP_063510179.1 | class I SAM-dependent methyltransferase | Machinery gene |
| MGAS11027_RS00625 (MGAS11027_0130) | - | 100620..101816 (+) | 1197 | WP_063510180.1 | acetate kinase | - |
| MGAS11027_RS00630 (MGAS11027_0131) | - | 102003..102311 (+) | 309 | WP_011284425.1 | hypothetical protein | - |
| MGAS11027_RS00635 (MGAS11027_0132) | proC | 102394..103164 (-) | 771 | WP_011284426.1 | pyrroline-5-carboxylate reductase | - |
| MGAS11027_RS00640 (MGAS11027_0133) | pepA | 103212..104279 (-) | 1068 | WP_011284427.1 | glutamyl aminopeptidase | - |
| MGAS11027_RS00645 (MGAS11027_0135) | - | 104744..105028 (+) | 285 | WP_002992749.1 | DUF4651 domain-containing protein | - |
| MGAS11027_RS00650 (MGAS11027_0136) | - | 105025..105342 (+) | 318 | WP_011284428.1 | thioredoxin family protein | - |
Sequence
Protein
Download Length: 317 a.a. Molecular weight: 35941.07 Da Isoelectric Point: 4.7866
>NTDB_id=164995 MGAS11027_RS00620 WP_063510179.1 99608..100561(+) (comYH) [Streptococcus pyogenes strain MGAS11027]
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDAIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
MTFEKIEEAYQLLLENCQLIENDLKTHIYDAIVEQNSFYLGAEGASPQVAQNSDKLKALCLTKEEWRKAYQFLFIKAAQT
EQLQANHQFTPDAIGFILLYLLEQLSDKDSLEVLEIGSGTGNLAQTLLNNTSKSLDYVGIELDDLLIDLSASIAEIMDSS
AHFIQEDAVRPQLLKESDIVISDLPVGYYPNDAIAKRYKVASSDKHTYAHHLLMEQSLKYLKKDGFAIFLAPVNLLTSPQ
SQLLKQWLKDYAQVVALITLPDSIFGHPSNAKSIIVLQKQTDHPMETFVYPIRDLKLAENIHDFMENFKKWKLSNVN
Nucleotide
Download Length: 954 bp
>NTDB_id=164995 MGAS11027_RS00620 WP_063510179.1 99608..100561(+) (comYH) [Streptococcus pyogenes strain MGAS11027]
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGCTATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACACTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
ATGACTTTTGAAAAAATTGAAGAAGCTTATCAGCTGCTCTTAGAGAACTGTCAACTAATTGAAAATGATCTAAAAACACA
TATATACGATGCCATTGTTGAACAAAACTCCTTTTATTTAGGGGCTGAGGGAGCTAGTCCTCAAGTTGCTCAAAATAGTG
ATAAACTGAAAGCCTTGTGCCTGACAAAAGAAGAATGGCGTAAGGCCTACCAGTTTCTTTTTATTAAGGCAGCTCAGACT
GAGCAACTCCAAGCCAACCATCAGTTCACACCAGATGCTATTGGCTTCATTCTGCTGTATCTTTTGGAACAATTGAGTGA
TAAAGATAGCTTAGAGGTACTTGAGATTGGAAGTGGAACAGGGAACCTAGCCCAAACCCTTCTCAACAACACGAGCAAGA
GCCTTGATTATGTAGGGATTGAACTTGATGATCTCTTGATTGATCTGTCAGCCAGTATTGCTGAGATAATGGATTCTTCA
GCTCATTTTATTCAAGAAGATGCGGTAAGGCCTCAATTACTAAAAGAAAGTGACATTGTCATCAGTGACTTACCAGTTGG
TTATTATCCTAACGATGCTATTGCCAAACGGTACAAGGTGGCTAGTTCAGATAAGCATACCTATGCCCATCATTTATTAA
TGGAACAGTCTTTAAAATACTTGAAAAAAGACGGTTTTGCGATTTTTCTGGCACCAGTCAATTTATTGACGAGCCCTCAG
AGCCAGTTATTGAAACAGTGGTTAAAAGATTATGCTCAGGTGGTGGCCTTGATTACACTACCAGATTCTATTTTTGGTCA
TCCCTCAAATGCCAAGTCCATTATTGTCTTACAAAAACAAACAGACCACCCAATGGAAACCTTTGTCTATCCAATTCGGG
ATTTGAAGCTTGCAGAGAATATTCATGATTTTATGGAAAATTTCAAAAAATGGAAACTGAGTAATGTCAATTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comYH | Streptococcus mutans UA159 |
66.139 |
99.685 |
0.659 |
| comYH | Streptococcus mutans UA140 |
65.823 |
99.685 |
0.656 |