Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   AU077_RS09240 Genome accession   NZ_CP013688
Coordinates   1852168..1853109 (-) Length   313 a.a.
NCBI ID   WP_014293763.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain ICDDRB-NRC-S1     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1847168..1858109
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  AU077_RS09200 (AU077_09200) - 1847258..1848457 (-) 1200 WP_014293771.1 acetate kinase -
  AU077_RS09205 (AU077_09205) comYH 1848510..1849466 (-) 957 WP_014293770.1 class I SAM-dependent methyltransferase Machinery gene
  AU077_RS09210 (AU077_09210) comYG 1849548..1849853 (-) 306 WP_058621961.1 competence type IV pilus minor pilin ComGG Machinery gene
  AU077_RS09215 (AU077_09215) comYF 1849825..1850292 (-) 468 WP_014293768.1 competence type IV pilus minor pilin ComGF Machinery gene
  AU077_RS09220 (AU077_09220) comGE 1850246..1850539 (-) 294 WP_044562943.1 competence type IV pilus minor pilin ComGE -
  AU077_RS09225 (AU077_09225) comYD 1850493..1850924 (-) 432 WP_014293766.1 competence type IV pilus minor pilin ComGD Machinery gene
  AU077_RS09230 (AU077_09230) comYC 1850908..1851201 (-) 294 WP_039670352.1 competence type IV pilus major pilin ComGC Machinery gene
  AU077_RS09235 (AU077_09235) comYB 1851201..1852286 (-) 1086 WP_014293764.1 competence type IV pilus assembly protein ComGB Machinery gene
  AU077_RS09240 (AU077_09240) comYA 1852168..1853109 (-) 942 WP_014293763.1 competence type IV pilus ATPase ComGA Machinery gene
  AU077_RS09245 (AU077_09245) - 1853219..1853548 (-) 330 WP_014293762.1 DUF1033 family protein -
  AU077_RS09250 (AU077_09250) rpoC 1853718..1857356 (-) 3639 WP_039670349.1 DNA-directed RNA polymerase subunit beta' -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35729.89 Da        Isoelectric Point: 5.3009

>NTDB_id=164079 AU077_RS09240 WP_014293763.1 1852168..1853109(-) (comYA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
MIQEKAKQLIKDAVEVNAQDIYILPREDCYEVYQRVGDQRQFVDYFELEQMTSLISHFKFVAGMNVGEKRRSQLGSCDYQ
FADEEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPNK
QVITIEDPVEIKQEQMLQLQLNSDIGMTYDELIKLSLRHRPDILIIGEIRDSETARAVIRASLTGAVVFSTIHAKSIPGV
YARLLELGLSKQELENSLRAIVYQRLIGGGGVIDFAKENFESHQPECWNTKIESLVKDGHITAEQAKIEKIAI

Nucleotide


Download         Length: 942 bp        

>NTDB_id=164079 AU077_RS09240 WP_014293763.1 1852168..1853109(-) (comYA) [Streptococcus gallolyticus strain ICDDRB-NRC-S1]
ATGATTCAGGAAAAAGCAAAGCAACTCATTAAGGATGCTGTTGAAGTTAATGCGCAAGATATTTACATTTTACCTAGAGA
AGACTGTTATGAAGTGTATCAACGCGTGGGAGACCAACGGCAATTTGTTGATTATTTTGAACTAGAGCAGATGACTAGCT
TGATTAGTCATTTTAAATTTGTGGCAGGTATGAATGTTGGGGAGAAACGTCGTAGTCAGTTAGGTTCTTGTGATTATCAA
TTTGCAGATGAGGAAGAGATTTCGCTTCGTTTGTCGAGTGTTGGTGATTATCGCGGACGAGAAAGTTTGGTGATTCGCTT
GCTTTATTCTGGTCGTCATGACTTGCAATATTGGTTTGACGGGATGAAAAATATTTTAGAAGCTATTGACAGTAGGGGGC
TTTACCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTGGTTCGTGAAAAATTTCCTAATAAG
CAAGTCATTACAATTGAGGATCCTGTTGAAATCAAACAGGAACAAATGTTGCAGTTGCAGTTAAATAGTGATATTGGGAT
GACTTATGACGAGCTGATTAAATTATCGCTTCGTCATAGACCAGATATTCTGATTATCGGAGAAATTCGTGATAGCGAGA
CAGCGCGTGCAGTTATTCGTGCGAGTTTGACGGGAGCTGTTGTATTTTCGACCATTCATGCGAAGAGCATCCCTGGCGTT
TACGCACGTCTTTTGGAATTGGGGCTTAGTAAGCAAGAATTGGAAAATAGTTTGCGTGCCATTGTTTATCAACGCTTAAT
TGGCGGAGGAGGTGTAATTGATTTTGCTAAAGAAAACTTTGAAAGTCACCAACCAGAGTGCTGGAATACAAAAATTGAAA
GTCTTGTTAAAGACGGACATATCACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

69.132

99.361

0.687
  comYA Streptococcus mutans UA140

68.81

99.361

0.684
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.419

99.042

0.668
  comYA Streptococcus gordonii str. Challis substr. CH1

65.273

99.361

0.649
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.5

99.681

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.272

100

0.553
  comGA Latilactobacillus sakei subsp. sakei 23K

43.116

88.179

0.38

Multiple sequence alignment