Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/comE2   Type   Regulator
Locus tag   ATM98_RS06900 Genome accession   NZ_CP013651
Coordinates   1447206..1447958 (-) Length   250 a.a.
NCBI ID   WP_048690420.1    Uniprot ID   -
Organism   Streptococcus sp. A12     
Function   activate transcription of early competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1442206..1452958
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ATM98_RS06880 (ATM98_06880) - 1442650..1444272 (+) 1623 WP_061564539.1 ATP-binding cassette domain-containing protein -
  ATM98_RS06885 (ATM98_06885) - 1444325..1446922 (+) 2598 WP_185759941.1 YfhO family protein -
  ATM98_RS06900 (ATM98_06900) comE/comE2 1447206..1447958 (-) 753 WP_048690420.1 response regulator transcription factor Regulator
  ATM98_RS09765 - 1447959..1449284 (-) 1326 WP_065426966.1 GHKL domain-containing protein -
  ATM98_RS09280 - 1449284..1449415 (-) 132 WP_082161867.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  ATM98_RS06915 (ATM98_06915) rlmH 1449772..1450251 (-) 480 WP_048690423.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  ATM98_RS06920 (ATM98_06920) htrA 1450453..1451631 (+) 1179 WP_061564541.1 S1C family serine protease Regulator
  ATM98_RS06925 (ATM98_06925) spo0J 1451697..1452458 (+) 762 WP_048690428.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29437.21 Da        Isoelectric Point: 8.4082

>NTDB_id=163415 ATM98_RS06900 WP_048690420.1 1447206..1447958(-) (comE/comE2) [Streptococcus sp. A12]
MNIVLLEDEISQQVRVEKHVKAIAEEEGLRLNIVSTSKIAELKEYLTNGDFHQLFFLDIDIKGDEKAGIKAAQMIREVNP
FAIIAFITTKSEFATITYRYKVSALEFIEKTLNENLFKEKIRECILYLKKNVIENKNIIDFFEYSFKNMEIRVPYRDILY
IETTGVSHKLRLVGKNFQKEFLGTIKDILEKDVDNHFFSPNQSYLVNQRMIVNFDRRKRLLMLEEETTCPVSRTQVKRVE
ELLNKIQKKA

Nucleotide


Download         Length: 753 bp        

>NTDB_id=163415 ATM98_RS06900 WP_048690420.1 1447206..1447958(-) (comE/comE2) [Streptococcus sp. A12]
ATGAATATTGTATTGCTAGAGGACGAAATTTCTCAACAAGTTCGAGTAGAGAAACATGTAAAAGCTATCGCTGAGGAGGA
AGGCCTACGATTAAATATTGTTTCCACCAGTAAAATAGCTGAACTAAAGGAATATCTAACCAATGGTGATTTTCATCAGC
TTTTCTTCCTGGACATTGATATCAAAGGGGATGAAAAAGCTGGTATCAAGGCAGCTCAAATGATTCGTGAGGTCAATCCT
TTTGCCATTATTGCCTTTATCACTACGAAATCGGAATTTGCAACCATTACCTATCGTTACAAGGTATCAGCTCTCGAATT
TATTGAAAAAACCTTGAATGAAAACTTATTTAAGGAAAAAATTCGAGAATGCATTCTCTACTTGAAGAAGAATGTGATTG
AAAATAAAAATATCATTGATTTCTTTGAGTATAGTTTCAAAAATATGGAAATTCGAGTTCCATATCGAGATATATTGTAC
ATTGAAACAACTGGAGTTTCCCACAAATTGCGACTTGTTGGAAAGAATTTTCAAAAGGAATTTTTAGGGACTATCAAGGA
TATACTTGAAAAAGATGTGGACAATCATTTCTTCAGTCCTAATCAGTCTTATCTAGTCAATCAAAGAATGATTGTCAATT
TTGATCGTCGCAAGAGACTTTTGATGTTAGAAGAGGAGACAACTTGCCCTGTTTCTCGTACACAGGTGAAAAGGGTCGAA
GAATTATTAAATAAAATACAGAAAAAGGCTTGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(18-121)

LytTr DNA-binding domain (LytTR)

(151-243)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/comE2 Streptococcus gordonii strain NCTC7865

50

100

0.5
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

50

100

0.5
  comE Streptococcus infantis strain Atu-4

48.8

100

0.488
  comE Streptococcus mitis SK321

47.6

100

0.476
  comE Streptococcus mitis NCTC 12261

47.6

100

0.476
  comE Streptococcus pneumoniae Rx1

46.8

100

0.468
  comE Streptococcus pneumoniae D39

46.8

100

0.468
  comE Streptococcus pneumoniae R6

46.8

100

0.468
  comE Streptococcus pneumoniae TIGR4

46.8

100

0.468
  comE/comE1 Streptococcus equinus JB1

37.805

98.4

0.372

Multiple sequence alignment