Detailed information NTG0156804

Bioinformatically predicted

Overview

• Name: comE
• Type: Regulator
• Locus tag: SanJ4206_RS09785
• Genome accession: NZ_CP012719
• Coordinates: 1996143..1996892 (-)
• Length: 249 a.a.
• NCBI ID: WP_157622123.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain J4206
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1991143..2001892

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4206_RS09765 (SanJ4206_1905)	-	1992221..1994797 (+)	2577	WP_003027897.1	YfhO family protein	-
SanJ4206_RS09770 (SanJ4206_1906c)	-	1994841..1995674 (-)	834	WP_022525263.1	ISL3 family transposase	-
SanJ4206_RS09785 (SanJ4206_1907c)	comE	1996143..1996892 (-)	750	WP_157622123.1	competence system response regulator transcription factor ComE	Regulator
SanJ4206_RS09790 (SanJ4206_1908c)	comD/comD2	1996892..1998214 (-)	1323	WP_232202911.1	sensor histidine kinase	Regulator
SanJ4206_RS09795 (SanJ4206_1909c)	-	1998235..1998381 (-)	147	WP_003029519.1	bacteriocin	-
SanJ4206_RS09805 (SanJ4206_1910c)	rlmH	1998663..1999142 (-)	480	WP_003029518.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SanJ4206_RS09810 (SanJ4206_1911)	htrA	1999335..2000525 (+)	1191	WP_003029517.1	S1C family serine protease	Regulator
SanJ4206_RS09815 (SanJ4206_1912)	spo0J	2000580..2001347 (+)	768	WP_003029516.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 249 a.a.
• Molecular weight: 29163.83 Da
• Isoelectric Point: 7.9203

>NTDB_id=156804 SanJ4206_RS09785 WP_157622123.1 1996143..1996892(-) (comE) [Streptococcus anginosus strain J4206]
MKVLVLEDEISHQVRMETTLAEIAKEMGITIKVKVTGKVREFKEYIENDEVNQLYFLDIDIKGEETKGLEIAKFICHHNP
YAIIVFVTTKSEFATMTFKYKVSALDFVDKNLSDIAFKKHIKDSIEYTKATLIENKDMVDYFEYSFRGGEVRMPFNDILY
IETTGSSHKLRIVGKNFFKEFYGTIADIQEKDKETRRFFSPHKSYLVNIGNIKGYDKKMREIIFYEDHRCPITRMKIGKL
KAILEELKG

Nucleotide

• Length: 750 bp

>NTDB_id=156804 SanJ4206_RS09785 WP_157622123.1 1996143..1996892(-) (comE) [Streptococcus anginosus strain J4206]
ATGAAAGTATTAGTATTAGAAGATGAAATTTCACATCAAGTAAGAATGGAAACAACTTTGGCAGAGATTGCGAAAGAAAT
GGGAATTACGATAAAAGTTAAAGTAACTGGCAAAGTAAGAGAATTTAAAGAATATATTGAAAATGATGAGGTGAATCAAT
TATATTTTTTAGATATTGATATCAAAGGAGAGGAAACAAAAGGTTTAGAAATAGCAAAATTTATATGTCATCACAATCCG
TATGCTATTATTGTTTTTGTTACAACGAAATCAGAATTTGCTACGATGACATTTAAATATAAAGTATCTGCACTGGATTT
TGTTGATAAAAATTTGAGTGATATTGCTTTTAAAAAACATATAAAAGACAGCATTGAGTATACAAAAGCGACATTGATTG
AAAATAAAGATATGGTGGATTATTTTGAATATAGCTTTCGTGGCGGAGAGGTTAGAATGCCTTTTAATGACATTTTATAT
ATTGAAACGACAGGCTCTTCTCATAAATTAAGAATTGTCGGTAAAAACTTTTTTAAAGAATTTTATGGTACTATTGCAGA
TATTCAAGAAAAAGATAAAGAAACAAGACGTTTCTTTTCACCTCATAAATCTTATCTAGTCAATATTGGAAACATCAAAG
GTTATGACAAAAAAATGCGAGAAATAATTTTTTATGAAGATCATCGTTGTCCGATTACTCGAATGAAAATTGGAAAGTTA
AAGGCTATTTTAGAGGAATTAAAAGGATAA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (152-244)

• Response regulator receiver domain (Response_reg) (3-121)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Streptococcus mitis NCTC 12261	70.204	98.394	0.691
comE/comE2	Streptococcus gordonii strain NCTC7865	70.082	97.992	0.687
comE/comE1	Streptococcus gordonii str. Challis substr. CH1	70.082	97.992	0.687
comE	Streptococcus infantis strain Atu-4	69.388	98.394	0.683
comE	Streptococcus mitis SK321	69.388	98.394	0.683
comE	Streptococcus pneumoniae Rx1	68.98	98.394	0.679
comE	Streptococcus pneumoniae D39	68.98	98.394	0.679
comE	Streptococcus pneumoniae R6	68.98	98.394	0.679
comE	Streptococcus pneumoniae TIGR4	68.98	98.394	0.679
comE/blpR	Streptococcus mutans UA159	39.759	100	0.398