Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/comD2   Type   Regulator
Locus tag   SanJ4206_RS09790 Genome accession   NZ_CP012719
Coordinates   1996892..1998214 (-) Length   440 a.a.
NCBI ID   WP_232202911.1    Uniprot ID   -
Organism   Streptococcus anginosus strain J4206     
Function   phosphorylation of ComE (predicted from homology)   
Competence regulation

Genomic Context

Location: 1991892..2003214
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SanJ4206_RS09765 (SanJ4206_1905) - 1992221..1994797 (+) 2577 WP_003027897.1 YfhO family protein -
  SanJ4206_RS09770 (SanJ4206_1906c) - 1994841..1995674 (-) 834 WP_022525263.1 ISL3 family transposase -
  SanJ4206_RS09785 (SanJ4206_1907c) comE 1996143..1996892 (-) 750 WP_157622123.1 competence system response regulator transcription factor ComE Regulator
  SanJ4206_RS09790 (SanJ4206_1908c) comD/comD2 1996892..1998214 (-) 1323 WP_232202911.1 sensor histidine kinase Regulator
  SanJ4206_RS09795 (SanJ4206_1909c) - 1998235..1998381 (-) 147 WP_003029519.1 bacteriocin -
  SanJ4206_RS09805 (SanJ4206_1910c) rlmH 1998663..1999142 (-) 480 WP_003029518.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  SanJ4206_RS09810 (SanJ4206_1911) htrA 1999335..2000525 (+) 1191 WP_003029517.1 S1C family serine protease Regulator
  SanJ4206_RS09815 (SanJ4206_1912) spo0J 2000580..2001347 (+) 768 WP_003029516.1 ParB/RepB/Spo0J family partition protein Regulator

Sequence

Protein


Download         Length: 440 a.a.        Molecular weight: 51992.74 Da        Isoelectric Point: 8.9107

>NTDB_id=156805 SanJ4206_RS09790 WP_232202911.1 1996892..1998214(-) (comD/comD2) [Streptococcus anginosus strain J4206]
MKIEFIHWIIFSIIEAVSVVYCYKKISRVNKVNIHFTLLCLGIVFLTDFTTLIHYSIRYMMFFIQPLFFYLYFFKVKKVK
KHLSVFLALFLSLAVSSSETFFSVIISSVTGDKFVDRYWGLFYIFINIISLVFILKAIDYFKFNFKYFKKADFKENIVQL
NFYLLFIHFLLNLSHWLSNMKNLNSFSSMIATICFLMFMSTLFYLQSIREKYEKEEQIKQKEREQLQLQKYTDEIVNLYN
EIRGFRHDYGGMLASFQSAIHTSNIKEVERIYQEVLVNANLQLRSDKYTYFDLNNVGDSALRSVMTQTLFKARDYNIELT
FEVKDFVKPLPIKLLDLVRMTSVLLNNAIEGSAESYQKTMNVSLVDLDTETILVIQNSRKKRPLDLEEIYQTDFSTKGEG
RGLGLSNIKEIINNYEGIILDTKIEDEYFTQVMRVRKEGL

Nucleotide


Download         Length: 1323 bp        

>NTDB_id=156805 SanJ4206_RS09790 WP_232202911.1 1996892..1998214(-) (comD/comD2) [Streptococcus anginosus strain J4206]
GTGAAAATAGAATTTATACATTGGATTATTTTCTCAATTATAGAAGCTGTTTCTGTTGTATACTGCTATAAGAAAATAAG
TAGAGTGAATAAAGTGAATATTCACTTTACTTTGTTGTGTTTAGGAATTGTATTTTTAACTGATTTCACTACTTTAATAC
ATTATTCCATTAGATATATGATGTTTTTTATTCAACCATTATTTTTTTATTTATATTTTTTTAAAGTAAAAAAAGTTAAA
AAACATCTTTCTGTATTTTTAGCACTATTTTTATCTTTAGCTGTGTCAAGTTCTGAAACCTTCTTTTCAGTCATTATTTC
TTCTGTTACAGGTGATAAGTTTGTTGATAGATACTGGGGATTGTTCTATATTTTTATCAATATCATTTCTTTAGTTTTTA
TTTTAAAAGCAATTGATTATTTTAAGTTTAATTTTAAATATTTTAAAAAGGCGGATTTTAAAGAGAATATTGTGCAATTA
AACTTTTATCTCTTATTTATTCATTTTTTATTAAATTTGTCGCATTGGCTTAGTAATATGAAAAATTTAAATAGTTTTTC
TAGTATGATTGCTACAATTTGCTTTTTAATGTTTATGTCAACTTTATTCTACTTACAATCTATTCGCGAAAAGTATGAAA
AAGAAGAACAAATTAAACAGAAAGAACGAGAACAACTACAATTACAAAAATATACAGATGAAATTGTTAATCTGTATAAT
GAAATTCGAGGTTTTCGTCACGATTATGGTGGGATGTTGGCAAGTTTTCAATCAGCTATTCATACAAGTAATATAAAAGA
AGTGGAGCGAATCTATCAGGAGGTTCTCGTAAATGCTAATTTACAGCTTCGTTCTGATAAATATACGTATTTTGATTTAA
ATAATGTTGGAGATTCAGCACTTAGAAGTGTTATGACGCAAACATTGTTTAAGGCACGAGATTACAATATAGAATTAACA
TTTGAAGTAAAAGATTTTGTTAAACCTTTGCCAATTAAATTGTTAGATTTGGTTAGAATGACAAGTGTTCTTTTGAATAA
TGCCATAGAAGGATCAGCAGAAAGTTATCAAAAAACGATGAATGTTTCTTTGGTGGATTTAGATACAGAAACAATCTTAG
TCATTCAAAATTCACGTAAGAAAAGACCGCTAGATTTAGAAGAGATTTACCAAACTGATTTTTCAACAAAGGGTGAAGGA
CGCGGTTTAGGCTTAAGCAATATCAAAGAAATTATTAACAACTATGAAGGAATTATCCTCGATACTAAAATTGAGGATGA
ATATTTTACACAAGTAATGAGAGTGCGGAAAGAAGGTTTATAA

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(333-432)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/comD2 Streptococcus gordonii strain NCTC7865

53.846

100

0.541
  comD/comD1 Streptococcus gordonii str. Challis substr. CH1

54.11

99.545

0.539
  comD Streptococcus mitis SK321

47.449

89.091

0.423
  comD Streptococcus mitis NCTC 12261

48.67

85.455

0.416
  comD/comD2 Streptococcus pneumoniae TIGR4

48.404

85.455

0.414
  comD/comD1 Streptococcus pneumoniae Rx1

47.872

85.455

0.409
  comD/comD1 Streptococcus pneumoniae D39

47.872

85.455

0.409
  comD/comD1 Streptococcus pneumoniae R6

47.872

85.455

0.409

Multiple sequence alignment