Detailed information NTG0156806

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: SanJ4206_RS09810
• Genome accession: NZ_CP012719
• Coordinates: 1999335..2000525 (+)
• Length: 396 a.a.
• NCBI ID: WP_003029517.1
• Uniprot ID: A0AAI9J965
• Organism: Streptococcus anginosus strain J4206
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1994335..2005525

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SanJ4206_RS09770 (SanJ4206_1906c)	-	1994841..1995674 (-)	834	WP_022525263.1	ISL3 family transposase	-
SanJ4206_RS09785 (SanJ4206_1907c)	comE	1996143..1996892 (-)	750	WP_157622123.1	competence system response regulator transcription factor ComE	Regulator
SanJ4206_RS09790 (SanJ4206_1908c)	comD/comD2	1996892..1998214 (-)	1323	WP_232202911.1	sensor histidine kinase	Regulator
SanJ4206_RS09795 (SanJ4206_1909c)	-	1998235..1998381 (-)	147	WP_003029519.1	bacteriocin	-
SanJ4206_RS09805 (SanJ4206_1910c)	rlmH	1998663..1999142 (-)	480	WP_003029518.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
SanJ4206_RS09810 (SanJ4206_1911)	htrA	1999335..2000525 (+)	1191	WP_003029517.1	S1C family serine protease	Regulator
SanJ4206_RS09815 (SanJ4206_1912)	spo0J	2000580..2001347 (+)	768	WP_003029516.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 396 a.a.
• Molecular weight: 41678.63 Da
• Isoelectric Point: 9.4264

>NTDB_id=156806 SanJ4206_RS09810 WP_003029517.1 1999335..2000525(+) (htrA) [Streptococcus anginosus strain J4206]
MKNSSNFTKKLLLLFMVLAIGFIGGLLGNLTSSKLSTNSSTTTKVNQVTTAYKNTNSTTQAVSKVKDAVVSVITYANNNS
QNSVFGNDDSNNNNDNSQQVASEGSGVIYKKDGKYAYLVTNTHVISGAKKVDIRLADGNKVPGEIVGSDTYSDISVVRIS
ADKVKSVAEFGDSSKLTVGETAIAIGSPLGSNYANTVTQGIISSLNRNVSLKSEDGQTISTQAIQTDTAINPGNSGGPLV
NIQGQVIGITSSKIANNGGTSVEGLGFAIPSNDVINIINQLEANGTVTRPALGIQMIDITNLSSSDLSRLKLPSKITSGV
VVRSAQSGMPAEGKLQKYDVITKVDDKEISSTSDLQSALYKHSIGDNIKITFYRDGKETTTTIKLTKSTKDLDSNN

Nucleotide

• Length: 1191 bp

>NTDB_id=156806 SanJ4206_RS09810 WP_003029517.1 1999335..2000525(+) (htrA) [Streptococcus anginosus strain J4206]
ATGAAAAACTCTTCAAATTTCACAAAAAAATTGTTATTGCTTTTCATGGTCTTAGCTATAGGTTTTATTGGTGGTTTACT
TGGAAACTTAACTTCATCTAAATTATCAACAAATAGCTCTACAACGACTAAAGTTAATCAAGTTACTACTGCTTATAAAA
ATACAAATTCCACAACACAAGCTGTGAGTAAAGTAAAAGATGCTGTTGTATCCGTTATTACCTATGCTAATAATAATTCA
CAAAACAGTGTGTTTGGAAATGATGATTCAAATAATAACAATGATAATTCTCAACAAGTAGCTAGCGAAGGGTCTGGAGT
TATTTATAAAAAAGATGGAAAATACGCTTACTTAGTAACCAATACTCACGTTATCAGTGGTGCTAAAAAAGTTGACATTC
GTTTAGCAGATGGTAATAAAGTTCCTGGAGAAATTGTAGGGTCAGATACTTATTCTGATATCTCCGTTGTTCGCATTAGT
GCTGATAAAGTAAAATCAGTTGCTGAATTTGGAGATTCTAGCAAATTGACTGTTGGTGAGACAGCTATTGCGATTGGAAG
TCCACTTGGTTCAAATTATGCTAATACTGTGACGCAAGGAATTATTTCTAGTTTAAATCGTAATGTTTCTCTAAAATCTG
AAGACGGACAAACGATTTCAACACAAGCTATTCAAACAGACACAGCTATTAACCCAGGGAACTCTGGTGGACCACTTGTG
AATATCCAAGGACAAGTAATTGGTATTACTTCAAGTAAAATAGCTAACAACGGCGGAACTTCGGTTGAAGGATTAGGATT
TGCTATTCCATCTAATGATGTTATAAACATTATTAACCAGTTAGAAGCAAATGGAACTGTTACACGACCAGCTCTAGGAA
TCCAAATGATTGACATCACTAATCTGTCTAGTTCAGATCTATCACGCTTAAAACTTCCATCAAAAATAACTAGTGGAGTT
GTCGTACGTTCAGCTCAATCTGGAATGCCAGCTGAAGGAAAACTTCAAAAATATGATGTGATTACAAAAGTAGATGATAA
AGAAATTTCTTCAACAAGTGATTTACAATCCGCTTTATACAAACATTCAATTGGTGACAACATAAAAATCACTTTCTATC
GTGATGGAAAAGAAACTACTACTACCATTAAGCTTACAAAATCTACAAAAGATTTAGATTCAAATAATTGA

Domains

Predicted by InterproScan.

• Peptidase family M50 (Peptidase_M50) (265-390)

• Trypsin-like peptidase domain (Trypsin_2) (104-249)

• PDZ domain (PDZ_2) (290-385)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus gordonii str. Challis substr. CH1	75.81	100	0.768
htrA	Streptococcus mitis NCTC 12261	72.544	100	0.727
htrA	Streptococcus pneumoniae Rx1	72.292	100	0.725
htrA	Streptococcus pneumoniae D39	72.292	100	0.725
htrA	Streptococcus pneumoniae R6	72.292	100	0.725
htrA	Streptococcus pneumoniae TIGR4	72.292	100	0.725
htrA	Streptococcus mutans UA159	55.216	99.242	0.548