Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   VAA049_RS00190 Genome accession   NZ_CP010811
Coordinates   38721..39836 (+) Length   371 a.a.
NCBI ID   WP_046121254.1    Uniprot ID   -
Organism   Vibrio cholerae strain 1154-74     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Genomic Context

Location: 33721..44836
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  VAA049_RS00170 (VAA049_32) rsmB 34644..35924 (-) 1281 WP_046121251.1 16S rRNA (cytosine(967)-C(5))-methyltransferase RsmB -
  VAA049_RS00175 (VAA049_33) fmt 35980..36927 (-) 948 WP_046121252.1 methionyl-tRNA formyltransferase -
  VAA049_RS00180 (VAA049_34) def 36945..37454 (-) 510 WP_000115010.1 peptide deformylase -
  VAA049_RS00185 (VAA049_35) - 37594..38721 (+) 1128 WP_046121253.1 LysM peptidoglycan-binding domain-containing protein -
  VAA049_RS00190 (VAA049_36) dprA 38721..39836 (+) 1116 WP_046121254.1 DNA-processing protein DprA Machinery gene
  VAA049_RS00195 (VAA049_37) - 39839..40315 (+) 477 WP_000979769.1 DUF494 family protein -
  VAA049_RS00200 (VAA049_38) - 40331..40897 (+) 567 WP_046121255.1 type I DNA topoisomerase -
  VAA049_RS00205 (VAA049_39) - 40970..42103 (-) 1134 WP_046121256.1 5-(carboxyamino)imidazole ribonucleotide synthase -
  VAA049_RS00210 (VAA049_40) purE 42107..42592 (-) 486 WP_000215774.1 5-(carboxyamino)imidazole ribonucleotide mutase -
  VAA049_RS00215 (VAA049_41) - 42759..43316 (+) 558 WP_002022527.1 L-threonylcarbamoyladenylate synthase -
  VAA049_RS00220 (VAA049_42) hemF 43335..44252 (+) 918 WP_000443979.1 oxygen-dependent coproporphyrinogen oxidase -

Sequence

Protein


Download         Length: 371 a.a.        Molecular weight: 39962.98 Da        Isoelectric Point: 7.1834

>NTDB_id=139926 VAA049_RS00190 WP_046121254.1 38721..39836(+) (dprA) [Vibrio cholerae strain 1154-74]
MKDQDLAAWLALCFTPKLGSKTISHLLATRLPAQLQSFTPKQWLACGLKPEQLVFLTTQAAKQAELCLQWRSAANNRYIV
TPHCPLYPRLLKEISSSPPVLFIEGIWEAVHDPAVAIVGSRNASVDGRQIARQFATELAQSGLVVTSGLALGIDGYAHDG
ALQAQGQTVAVLGSGLAQVYPKQHQGLAERIIAQGALVSEFAPHTPPKADHFPRRNRIISGLSLGVVVVEAAEKSGSLIT
ARYAAEQGREVFVVPGSIFNAASQGSNQLIRQGACLVQSVQQIHQELKNALTWSLSEQVPYQATLFSAVQGDEELPFPEL
LANVGIEATPIDILASRTQIPVQDIMMQLLELELLGHVVAVPGGYIRKGRG

Nucleotide


Download         Length: 1116 bp        

>NTDB_id=139926 VAA049_RS00190 WP_046121254.1 38721..39836(+) (dprA) [Vibrio cholerae strain 1154-74]
ATGAAAGATCAGGATTTAGCGGCATGGTTGGCGCTCTGTTTTACTCCTAAACTAGGCAGCAAAACCATTTCTCACCTGCT
TGCGACCCGTTTGCCAGCCCAGTTGCAAAGTTTTACGCCTAAGCAATGGTTGGCCTGCGGGCTTAAGCCCGAACAACTGG
TGTTTTTAACCACTCAAGCGGCTAAACAAGCCGAGCTGTGTTTGCAATGGCGATCAGCAGCCAATAACCGCTATATCGTC
ACTCCTCATTGCCCACTTTACCCTCGTTTATTGAAAGAGATTAGCTCATCGCCTCCCGTCCTGTTTATTGAAGGAATATG
GGAAGCGGTGCATGACCCTGCGGTGGCTATCGTCGGTAGCCGCAATGCCAGTGTTGATGGGCGGCAGATCGCTCGCCAGT
TTGCCACTGAGCTCGCGCAGTCAGGTTTAGTGGTCACCAGTGGTTTAGCGCTTGGTATTGATGGTTATGCGCACGATGGC
GCTTTGCAAGCACAAGGGCAAACCGTAGCAGTATTAGGTTCAGGGCTGGCGCAGGTTTACCCCAAACAGCATCAAGGGTT
AGCGGAGCGAATCATCGCCCAAGGGGCCTTGGTTTCTGAGTTTGCCCCTCACACACCTCCTAAAGCGGATCACTTTCCGC
GCCGTAACCGAATTATCAGCGGCTTATCGCTCGGTGTTGTGGTGGTAGAAGCGGCGGAGAAAAGCGGCTCACTCATCACT
GCACGCTACGCCGCTGAGCAAGGGCGTGAGGTCTTTGTGGTTCCTGGCTCGATTTTTAATGCTGCCAGCCAAGGTAGCAA
TCAATTGATTCGCCAAGGCGCTTGTTTGGTGCAAAGTGTGCAACAAATTCATCAAGAGCTCAAAAATGCGCTGACTTGGT
CACTCTCTGAACAAGTTCCTTATCAAGCAACACTTTTTTCTGCTGTACAGGGCGATGAAGAATTGCCATTTCCCGAGCTG
TTAGCTAACGTAGGAATAGAAGCTACACCTATTGATATTCTCGCAAGCCGGACCCAGATACCGGTGCAAGATATCATGAT
GCAGCTCTTGGAGCTTGAGCTCCTTGGGCATGTGGTTGCAGTACCTGGTGGCTATATTAGAAAGGGGAGAGGCTAG

Domains

Predicted by InterproScan.

DprA winged helix domain (DprA_WH)

(319-364)

DNA recombination-mediator protein A (DNA_processg_A)

(77-278)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Vibrio cholerae strain A1552

99.191

100

0.992
  dprA Vibrio campbellii strain DS40M4

58.108

99.73

0.58
  dprA Glaesserella parasuis strain SC1401

43.617

100

0.442
  dprA Legionella pneumophila strain ERS1305867

43.316

100

0.437
  dprA Neisseria meningitidis strain C311

37.845

100

0.407
  dprA Neisseria meningitidis MC58

37.845

100

0.407
  dprA Neisseria gonorrhoeae strain FA1090

37.028

100

0.396
  dprA Neisseria gonorrhoeae MS11

36.203

100

0.385
  dprA Acinetobacter baumannii D1279779

43.202

89.218

0.385
  dprA Acinetobacter baumannii strain A118

42.9

89.218

0.383
  dprA Acinetobacter baylyi ADP1

41.742

89.757

0.375
  dprA Haemophilus influenzae Rd KW20

48.746

75.202

0.367

Multiple sequence alignment