Detailed information NTG0121240

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: DK43_RS08905
• Genome accession: NZ_CP007573
• Coordinates: 1846426..1846743 (-)
• Length: 105 a.a.
• NCBI ID: WP_003028473.1
• Uniprot ID: A0A0P0N5S2
• Organism: Streptococcus anginosus strain SA1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1841426..1851743

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK43_RS08875 (DK43_09095)	-	1842778..1843977 (-)	1200	WP_003028479.1	acetate kinase	-
DK43_RS08880 (DK43_09100)	comYH	1844024..1844977 (-)	954	WP_003028478.1	class I SAM-dependent methyltransferase	Machinery gene
DK43_RS08885 (DK43_09105)	comGG	1845045..1845371 (-)	327	WP_003028477.1	competence type IV pilus minor pilin ComGG	-
DK43_RS08890 (DK43_09110)	comGF/cglF	1845352..1845789 (-)	438	WP_003028476.1	competence type IV pilus minor pilin ComGF	Machinery gene
DK43_RS08895 (DK43_09115)	comGE/cglE	1845773..1846066 (-)	294	WP_003028475.1	competence type IV pilus minor pilin ComGE	Machinery gene
DK43_RS08900 (DK43_09120)	comYD	1846038..1846436 (-)	399	WP_003028474.1	competence type IV pilus minor pilin ComGD	Machinery gene
DK43_RS08905 (DK43_09125)	comYC	1846426..1846743 (-)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
DK43_RS08910 (DK43_09130)	comYB	1846740..1847762 (-)	1023	WP_003028472.1	competence type IV pilus assembly protein ComGB	Machinery gene
DK43_RS08915 (DK43_09135)	comYA	1847704..1848645 (-)	942	WP_003028470.1	competence type IV pilus ATPase ComGA	Machinery gene
DK43_RS08920 (DK43_09140)	-	1848715..1849080 (-)	366	WP_022525291.1	DUF1033 family protein	-
DK43_RS08925 (DK43_09145)	glnA	1849265..1850611 (-)	1347	WP_022525292.1	type I glutamate--ammonia ligase	-
DK43_RS08930 (DK43_09150)	-	1850650..1851009 (-)	360	WP_003028467.1	MerR family transcriptional regulator	-
DK43_RS08935 (DK43_09155)	-	1851086..1851616 (-)	531	WP_003028466.1	aromatic acid exporter family protein	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11622.72 Da
• Isoelectric Point: 10.1006

>NTDB_id=121240 DK43_RS08905 WP_003028473.1 1846426..1846743(-) (comYC) [Streptococcus anginosus strain SA1]
MKKLKSLKVKGFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVNEGT
ITDKQAASYKAYYAKHTKEARSVAD

Nucleotide

• Length: 318 bp

>NTDB_id=121240 DK43_RS08905 WP_003028473.1 1846426..1846743(-) (comYC) [Streptococcus anginosus strain SA1]
ATGAAAAAATTAAAAAGTTTGAAGGTTAAAGGTTTTACTTTAGTAGAGATGTTAGTCGTGCTTCTTATCATCAGTGTTTT
GATGCTCTTATTTGTACCGAATTTGACCAAGCAAAAAGAAGCGGTGACGGAAAAAGGAAATGCAGCGGTGGTAAAAGTTG
TGGAAAGCCAAGCGGAGCTGTTTGAGGTCAATCACACTAATGAAAAAGCGACACTCTCAAAATTAGTCAACGAAGGTACG
ATTACAGACAAGCAAGCGGCATCTTATAAGGCTTACTATGCGAAACATACAAAAGAAGCTCGTTCCGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0P0N5S2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	73.333	100	0.733
comYC	Streptococcus mutans UA159	66.667	100	0.667
comYC	Streptococcus mutans UA140	66.667	100	0.667
comGC/cglC	Streptococcus mitis NCTC 12261	68.627	97.143	0.667
comGC/cglC	Streptococcus mitis SK321	68.627	97.143	0.667
comGC/cglC	Streptococcus pneumoniae R6	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae D39	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae Rx1	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	66.667	97.143	0.648
comYC	Streptococcus suis isolate S10	66.292	84.762	0.562
comGC	Lactococcus lactis subsp. cremoris KW2	54.808	99.048	0.543