Detailed information NTG0121237

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: DK43_RS08890
• Genome accession: NZ_CP007573
• Coordinates: 1845352..1845789 (-)
• Length: 145 a.a.
• NCBI ID: WP_003028476.1
• Uniprot ID: -
• Organism: Streptococcus anginosus strain SA1
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1840352..1850789

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
DK43_RS08870 (DK43_09090)	glmS	1840575..1842389 (-)	1815	WP_003028480.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-
DK43_RS08875 (DK43_09095)	-	1842778..1843977 (-)	1200	WP_003028479.1	acetate kinase	-
DK43_RS08880 (DK43_09100)	comYH	1844024..1844977 (-)	954	WP_003028478.1	class I SAM-dependent methyltransferase	Machinery gene
DK43_RS08885 (DK43_09105)	comGG	1845045..1845371 (-)	327	WP_003028477.1	competence type IV pilus minor pilin ComGG	-
DK43_RS08890 (DK43_09110)	comGF/cglF	1845352..1845789 (-)	438	WP_003028476.1	competence type IV pilus minor pilin ComGF	Machinery gene
DK43_RS08895 (DK43_09115)	comGE/cglE	1845773..1846066 (-)	294	WP_003028475.1	competence type IV pilus minor pilin ComGE	Machinery gene
DK43_RS08900 (DK43_09120)	comYD	1846038..1846436 (-)	399	WP_003028474.1	competence type IV pilus minor pilin ComGD	Machinery gene
DK43_RS08905 (DK43_09125)	comYC	1846426..1846743 (-)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
DK43_RS08910 (DK43_09130)	comYB	1846740..1847762 (-)	1023	WP_003028472.1	competence type IV pilus assembly protein ComGB	Machinery gene
DK43_RS08915 (DK43_09135)	comYA	1847704..1848645 (-)	942	WP_003028470.1	competence type IV pilus ATPase ComGA	Machinery gene
DK43_RS08920 (DK43_09140)	-	1848715..1849080 (-)	366	WP_022525291.1	DUF1033 family protein	-
DK43_RS08925 (DK43_09145)	glnA	1849265..1850611 (-)	1347	WP_022525292.1	type I glutamate--ammonia ligase	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16857.45 Da
• Isoelectric Point: 10.2436

>NTDB_id=121237 DK43_RS08890 WP_003028476.1 1845352..1845789(-) (comGF/cglF) [Streptococcus anginosus strain SA1]
MFKANKVKAFTLLEALIALFVLSGSVLLFQSMTRLLAFEVQARQHSEQREWLLFADQLEAELARSSFEKVENNRLYMKQD
GKVIAFGKSSGRDFRKTNANGKGYQPMVYDVKKAEISQKNELIHVRLTFRRGLEREFVYRVETES

Nucleotide

• Length: 438 bp

>NTDB_id=121237 DK43_RS08890 WP_003028476.1 1845352..1845789(-) (comGF/cglF) [Streptococcus anginosus strain SA1]
GTGTTCAAGGCAAATAAAGTGAAAGCTTTTACCCTTTTAGAGGCTCTGATTGCCTTATTTGTACTCAGCGGAAGTGTGCT
GCTTTTTCAGTCAATGACGCGTCTTCTGGCTTTTGAAGTTCAAGCCCGGCAACATAGTGAACAACGAGAATGGCTTTTGT
TTGCTGATCAACTAGAAGCAGAGTTGGCTCGTTCTTCATTTGAAAAGGTGGAGAATAATCGTTTATATATGAAACAGGAC
GGCAAGGTGATTGCATTTGGAAAGTCAAGTGGACGTGATTTTAGAAAAACCAATGCGAATGGGAAAGGTTACCAGCCGAT
GGTTTATGATGTGAAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTCATGTCAGACTGACGTTTAGGCGAGGATTAG
AAAGGGAGTTTGTCTATCGTGTGGAAACAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae R6	65.493	97.931	0.641
comGF/cglF	Streptococcus pneumoniae TIGR4	65.493	97.931	0.641
comGF/cglF	Streptococcus pneumoniae Rx1	65.493	97.931	0.641
comGF/cglF	Streptococcus pneumoniae D39	65.493	97.931	0.641
comGF/cglF	Streptococcus mitis NCTC 12261	65.714	96.552	0.634
comGF/cglF	Streptococcus mitis SK321	65.714	96.552	0.634
comYF	Streptococcus mutans UA159	43.704	93.103	0.407
comYF	Streptococcus mutans UA140	43.704	93.103	0.407
comGF	Lactococcus lactis subsp. cremoris KW2	41.481	93.103	0.386