Detailed information NTG1145972

Bioinformatically predicted

Overview

• Name: comYA
• Type: Machinery gene
• Locus tag: BUC38_RS00770
• Genome accession: NZ_LT671674
• Coordinates: 127821..128771 (+)
• Length: 316 a.a.
• NCBI ID: WP_044690427.1
• Uniprot ID: A0A116MCT9
• Organism: Streptococcus suis strain LS9N
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 122821..133771

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BUC38_RS00760	-	126238..126603 (+)	366	WP_029998791.1	DUF1033 family protein	-
BUC38_RS00765	-	126638..127549 (-)	912	Protein_113	S66 peptidase family protein	-
BUC38_RS00770	comYA	127821..128771 (+)	951	WP_044690427.1	competence type IV pilus ATPase ComGA	Machinery gene
BUC38_RS00775	comYB	128683..129720 (+)	1038	WP_044690426.1	competence type IV pilus assembly protein ComGB	Machinery gene
BUC38_RS00780	comYC	129722..130003 (+)	282	WP_024376296.1	competence type IV pilus major pilin ComGC	Machinery gene
BUC38_RS00785	comGD	129984..130391 (+)	408	WP_004195585.1	competence type IV pilus minor pilin ComGD	-
BUC38_RS00790	comYE	130363..130656 (+)	294	WP_044690424.1	competence type IV pilus minor pilin ComGE	Machinery gene
BUC38_RS00795	comGF/cglF	130643..131077 (+)	435	WP_044690423.1	competence type IV pilus minor pilin ComGF	Machinery gene
BUC38_RS00800	comGG	131055..131567 (+)	513	WP_061704561.1	competence type IV pilus minor pilin ComGG	-

Sequence

Protein

• Length: 316 a.a.
• Molecular weight: 35412.26 Da
• Isoelectric Point: 5.4744

>NTDB_id=1145972 BUC38_RS00770 WP_044690427.1 127821..128771(+) (comYA) [Streptococcus suis strain LS9N]
MIQEKARKMIEEAVADRVSDIYLVPRGECYQVYHRIMDEREFVQDVAEEEVTAIISHFKFLAGLNVGEKRRSQQGSCDYD
YGSGEISLRLSTVGDYRGKESLVIRLLYDNDKELKFWFEAAERLAEEIKGRGLYLFSGPVGSGKTTLMYHLARLKFPDKQ
ILTIEDPVEIKQEDMLQLQLNEAIGATYDNLIKLSLRHRPDLLIIGEIRDAETARAVIRASLTGATVFSTVHARSISGVY
ARMLELGVSPEELNNALQGIAYQRLIGGGGVVDFAKGNYQNHSADQWNAQIDRLFAAGHISLRQAETEKIALGSPA

Nucleotide

• Length: 951 bp

>NTDB_id=1145972 BUC38_RS00770 WP_044690427.1 127821..128771(+) (comYA) [Streptococcus suis strain LS9N]
ATGATTCAAGAAAAAGCAAGAAAGATGATTGAAGAGGCGGTGGCAGATAGGGTCAGTGACATCTATCTAGTTCCTCGAGG
TGAGTGTTACCAAGTCTACCATCGTATCATGGACGAGCGGGAATTTGTGCAAGACGTGGCTGAGGAGGAAGTAACAGCCA
TCATCAGCCATTTCAAGTTTTTAGCAGGATTAAATGTTGGTGAAAAACGCCGTAGCCAGCAGGGTTCCTGTGACTATGAT
TATGGGAGCGGAGAGATTTCACTTCGCTTATCAACTGTCGGTGATTATCGTGGCAAGGAAAGTCTGGTTATCCGCCTACT
CTATGACAATGACAAGGAACTCAAGTTCTGGTTTGAGGCGGCCGAGCGGCTTGCAGAAGAAATCAAGGGACGAGGGCTCT
ACCTTTTTTCGGGTCCAGTCGGCTCTGGTAAGACCACGCTTATGTACCATCTTGCCAGGCTGAAATTCCCAGACAAGCAG
ATTTTGACCATTGAAGATCCAGTCGAAATCAAGCAGGAGGACATGCTGCAACTCCAGCTCAATGAAGCCATCGGAGCCAC
CTACGACAATTTGATAAAATTATCCCTGCGTCATCGACCGGACCTGCTCATCATCGGTGAAATTCGGGATGCGGAAACAG
CTCGAGCAGTCATTCGAGCCAGCCTGACGGGAGCTACCGTTTTCTCAACGGTTCACGCAAGGTCTATTTCGGGTGTCTAT
GCTCGTATGTTGGAATTGGGGGTCAGTCCTGAAGAGTTAAATAATGCCCTTCAAGGCATTGCCTATCAACGCTTGATCGG
GGGAGGAGGTGTAGTAGATTTTGCAAAGGGAAATTACCAAAACCATTCCGCAGACCAGTGGAATGCGCAAATTGATCGGC
TTTTTGCAGCAGGACATATCAGTCTTCGGCAGGCAGAAACAGAAAAAATTGCCCTTGGCTCGCCAGCGTAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (8-266)

3D structure

• AlphaFold DB: A0A116MCT9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYA	Streptococcus gordonii str. Challis substr. CH1	69.032	98.101	0.677
comYA	Streptococcus mutans UA159	67.846	98.418	0.668
comYA	Streptococcus mutans UA140	67.846	98.418	0.668
comGA/cglA/cilD	Streptococcus pneumoniae Rx1	65.273	98.418	0.642
comGA/cglA/cilD	Streptococcus mitis NCTC 12261	65.273	98.418	0.642
comGA/cglA/cilD	Streptococcus pneumoniae R6	65.273	98.418	0.642
comGA/cglA/cilD	Streptococcus pneumoniae TIGR4	65.273	98.418	0.642
comGA/cglA/cilD	Streptococcus pneumoniae D39	65.273	98.418	0.642
comGA/cglA	Streptococcus sobrinus strain NIDR 6715-7	64.839	98.101	0.636
comGA	Lactococcus lactis subsp. cremoris KW2	53.628	100	0.538