Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQN21_RS00645 Genome accession   NZ_LS483409
Coordinates   95365..96306 (+) Length   313 a.a.
NCBI ID   WP_077495921.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 90365..101306
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS00635 (NCTC13773_00127) rpoC 91117..94755 (+) 3639 WP_012961326.1 DNA-directed RNA polymerase subunit beta' -
  DQN21_RS00640 (NCTC13773_00128) - 94926..95294 (+) 369 WP_074658936.1 DUF1033 family protein -
  DQN21_RS00645 (NCTC13773_00129) comYA 95365..96306 (+) 942 WP_077495921.1 competence type IV pilus ATPase ComGA Machinery gene
  DQN21_RS00650 (NCTC13773_00130) comYB 96188..97273 (+) 1086 WP_231873059.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN21_RS00655 (NCTC13773_00131) comYC 97273..97566 (+) 294 WP_039695588.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN21_RS00660 (NCTC13773_00132) comYD 97550..97981 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQN21_RS00665 (NCTC13773_00133) comGE 97935..98228 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE -
  DQN21_RS00670 (NCTC13773_00134) comYF 98182..98649 (+) 468 WP_012961330.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQN21_RS00675 (NCTC13773_00135) comGG 98603..98953 (+) 351 WP_420031090.1 competence type IV pilus minor pilin ComGG -
  DQN21_RS00680 (NCTC13773_00136) comYH 99008..99964 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  DQN21_RS00685 (NCTC13773_00137) - 100017..101216 (+) 1200 WP_061458770.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35757.94 Da        Isoelectric Point: 5.4957

>NTDB_id=1140534 DQN21_RS00645 WP_077495921.1 95365..96306(+) (comYA) [Streptococcus gallolyticus strain NCTC13773]
MIQEKAKQLIKEAVEVNAQDIYILPREDCYEVYQRVGDQRQFVDYFELEQMTSLISHFKFVAGMNVGEKRRSQLGSCDYQ
FADEEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMKNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPNK
QVITIEDPVEIKQEQMLQLQLNSDIGMTYDELIKLSLRHRPDILIIGEIRDSETARAVIRASLTGAVVFSTIHAKSIPGV
YARLLELGVSKQELENSLRAIVYQRLIGGGGVIDFAKENFESHRPECWNTKIESLVKDGHITAEQAKIEKIAI

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1140534 DQN21_RS00645 WP_077495921.1 95365..96306(+) (comYA) [Streptococcus gallolyticus strain NCTC13773]
ATGATTCAGGAAAAAGCAAAGCAACTCATTAAGGAGGCTGTTGAAGTTAATGCGCAAGATATTTACATTTTACCTAGAGA
AGACTGTTATGAAGTGTATCAACGCGTGGGAGACCAACGGCAATTTGTTGATTATTTTGAGCTAGAGCAGATGACTAGCT
TGATTAGTCATTTTAAATTTGTGGCTGGTATGAATGTTGGGGAGAAACGTCGCAGCCAGCTAGGTTCTTGTGATTATCAA
TTTGCAGATGAGGAAGAGATTTCGCTTCGTTTGTCGAGTGTTGGTGATTATCGTGGACGAGAAAGTTTAGTGATTCGCTT
GCTTTATTCTGGTCGTCATGATTTACAATATTGGTTTGACGGGATGAAAAATATTTTAGAAGCCATTGATAGTAGGGGGC
TTTACCTTTTTTCGGGACCAGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTGGTTCGTGAAAAATTTCCTAATAAG
CAAGTCATTACAATTGAGGACCCTGTTGAAATCAAACAGGAACAAATGTTGCAGTTGCAGTTAAATAGTGATATTGGGAT
GACTTATGACGAGCTGATTAAATTATCGCTTCGCCATAGACCAGATATTCTGATTATCGGAGAAATTCGTGATAGCGAGA
CAGCGCGTGCAGTTATTCGTGCGAGTTTGACGGGAGCTGTTGTATTTTCGACTATTCATGCGAAGAGCATCCCTGGCGTT
TACGCACGTCTTTTGGAATTAGGGGTTAGTAAGCAAGAATTGGAAAATAGTTTGCGTGCCATTGTTTATCAACGCTTAAT
TGGCGGAGGAGGTGTGATTGATTTTGCTAAAGAAAACTTTGAAAGTCACCGACCAGAGTGCTGGAATACAAAAATTGAAA
GTCTTGTTAAAGACGGACATATCACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

69.453

99.361

0.69
  comYA Streptococcus mutans UA140

69.132

99.361

0.687
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

67.419

99.042

0.668
  comYA Streptococcus gordonii str. Challis substr. CH1

65.595

99.361

0.652
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

62.821

99.681

0.626
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae D39

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae R6

62.5

99.681

0.623
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

62.5

99.681

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

54.952

100

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

43.116

88.179

0.38

Multiple sequence alignment