Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   DQN21_RS00650 Genome accession   NZ_LS483409
Coordinates   96188..97273 (+) Length   361 a.a.
NCBI ID   WP_231873059.1    Uniprot ID   -
Organism   Streptococcus gallolyticus strain NCTC13773     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 91188..102273
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQN21_RS00640 (NCTC13773_00128) - 94926..95294 (+) 369 WP_074658936.1 DUF1033 family protein -
  DQN21_RS00645 (NCTC13773_00129) comYA 95365..96306 (+) 942 WP_077495921.1 competence type IV pilus ATPase ComGA Machinery gene
  DQN21_RS00650 (NCTC13773_00130) comYB 96188..97273 (+) 1086 WP_231873059.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQN21_RS00655 (NCTC13773_00131) comYC 97273..97566 (+) 294 WP_039695588.1 competence type IV pilus major pilin ComGC Machinery gene
  DQN21_RS00660 (NCTC13773_00132) comYD 97550..97981 (+) 432 WP_009853232.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQN21_RS00665 (NCTC13773_00133) comGE 97935..98228 (+) 294 WP_012961329.1 competence type IV pilus minor pilin ComGE -
  DQN21_RS00670 (NCTC13773_00134) comYF 98182..98649 (+) 468 WP_012961330.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQN21_RS00675 (NCTC13773_00135) comGG 98603..98953 (+) 351 WP_420031090.1 competence type IV pilus minor pilin ComGG -
  DQN21_RS00680 (NCTC13773_00136) comYH 99008..99964 (+) 957 WP_009853236.1 class I SAM-dependent methyltransferase Machinery gene
  DQN21_RS00685 (NCTC13773_00137) - 100017..101216 (+) 1200 WP_061458770.1 acetate kinase -
  DQN21_RS00690 (NCTC13773_00138) - 101378..101578 (+) 201 WP_012961332.1 helix-turn-helix transcriptional regulator -
  DQN21_RS00700 (NCTC13773_00139) - 101810..102262 (+) 453 WP_061458772.1 hypothetical protein -

Sequence

Protein


Download         Length: 361 a.a.        Molecular weight: 41121.89 Da        Isoelectric Point: 9.9289

>NTDB_id=1140535 DQN21_RS00650 WP_231873059.1 96188..97273(+) (comYB) [Streptococcus gallolyticus strain NCTC13773]
MLKKTLKVTDQSAGIQKLKVLLKTDISQLNKQKSKKLPFKKQRKVIQLFNNLFESGFNLTEIVSFLRRSQLLLDIYVERM
QESLLNGASLATMMADLGFSDNIVTQIALADVHGNSQKSLLKIESYLSSMTVVRKKLIEVATYPLILLLFLILIMLGLKN
YLLPQLESQNVATQIITHFPTIFLLSIFSIGVLLACATFYARRLSQIDLYSRISRIPLVGNYVRLYLTAYYAREWGNLIG
QGIELMAIVGIMQKQKSLLFQEIGKDMEEALLSGQAFHQKVLGYPFFLRELSLMIEYGEVKSKLGRELDIYAEETWQSFF
GKLTQATQLIQPLVFVFVALIIVLIYVAMLLPMYQNMGGNF

Nucleotide


Download         Length: 1086 bp        

>NTDB_id=1140535 DQN21_RS00650 WP_231873059.1 96188..97273(+) (comYB) [Streptococcus gallolyticus strain NCTC13773]
TTGCTAAAGAAAACTTTGAAAGTCACCGACCAGAGTGCTGGAATACAAAAATTGAAAGTCTTGTTAAAGACGGACATATC
ACAGCTGAACAAGCAAAAATCGAAAAAATTGCCATTTAAAAAACAGCGCAAGGTTATTCAACTCTTTAATAATCTTTTTG
AAAGTGGGTTTAATTTAACAGAAATCGTGTCTTTTCTCCGAAGAAGTCAATTGTTGTTAGACATTTATGTTGAGAGAATG
CAAGAAAGTTTGTTAAATGGTGCTAGCCTAGCAACAATGATGGCAGATTTAGGGTTTTCAGACAATATTGTCACACAAAT
TGCTTTGGCTGATGTTCATGGAAACAGTCAGAAAAGTCTGCTGAAGATTGAGTCTTACCTTTCTAGCATGACTGTCGTCA
GAAAAAAGTTGATTGAAGTTGCAACGTATCCATTGATTTTGTTGTTGTTTCTTATTTTGATTATGCTGGGGTTGAAGAAT
TATCTACTGCCACAGCTGGAAAGCCAAAATGTGGCAACGCAGATTATTACGCATTTTCCAACGATTTTTTTGCTAAGTAT
TTTCTCGATTGGAGTGTTACTTGCTTGTGCGACATTTTATGCTAGGCGTTTATCGCAGATTGATTTATATAGTCGAATAA
GCCGGATTCCACTTGTGGGAAACTATGTTAGGTTATATTTGACAGCTTACTATGCGCGTGAATGGGGAAATTTGATTGGG
CAAGGTATTGAATTAATGGCAATCGTGGGAATCATGCAAAAGCAAAAGTCGCTCTTGTTTCAAGAGATTGGAAAGGATAT
GGAAGAAGCGTTGCTTTCAGGGCAAGCTTTTCATCAAAAAGTTCTGGGCTATCCATTCTTTTTGCGAGAATTGAGCCTAA
TGATTGAATATGGTGAGGTCAAATCGAAGCTTGGGCGTGAGTTAGACATTTATGCTGAGGAAACATGGCAGAGCTTCTTT
GGCAAATTGACCCAAGCAACACAGCTCATTCAACCACTTGTTTTTGTCTTTGTGGCTTTGATTATTGTATTAATTTATGT
GGCAATGCTGTTGCCAATGTATCAAAATATGGGAGGAAATTTTTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(232-352)

Type II secretion system (T2SS), protein F (T2SSF)

(47-164)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

66.772

87.535

0.584
  comYB Streptococcus mutans UA159

66.456

87.535

0.582
  comGB/cglB Streptococcus mitis NCTC 12261

60.767

93.906

0.571
  comYB Streptococcus gordonii str. Challis substr. CH1

60.417

93.075

0.562
  comGB/cglB Streptococcus mitis SK321

57.864

93.352

0.54
  comGB/cglB Streptococcus pneumoniae Rx1

56.973

93.352

0.532
  comGB/cglB Streptococcus pneumoniae D39

56.973

93.352

0.532
  comGB/cglB Streptococcus pneumoniae R6

56.973

93.352

0.532
  comGB/cglB Streptococcus pneumoniae TIGR4

56.973

93.352

0.532
  comGB Lactococcus lactis subsp. cremoris KW2

50

94.737

0.474

Multiple sequence alignment