Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   DQM67_RS09475 Genome accession   NZ_LS483383
Coordinates   1853852..1854793 (-) Length   313 a.a.
NCBI ID   WP_005591533.1    Uniprot ID   A0AAV3EFW6
Organism   Streptococcus cristatus ATCC 51100 strain NCTC 12479     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1848852..1859793
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQM67_RS09440 (NCTC12479_01828) comYH 1850075..1851040 (-) 966 WP_005591540.1 class I SAM-dependent methyltransferase Machinery gene
  DQM67_RS09445 (NCTC12479_01829) comGG 1851121..1851519 (-) 399 WP_005591539.1 competence type IV pilus minor pilin ComGG -
  DQM67_RS09450 (NCTC12479_01830) comGF/cglF 1851500..1851937 (-) 438 WP_005591538.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQM67_RS09455 (NCTC12479_01831) comGE 1851921..1852214 (-) 294 WP_174263560.1 competence type IV pilus minor pilin ComGE -
  DQM67_RS09460 (NCTC12479_01832) comYD 1852180..1852614 (-) 435 WP_037586086.1 competence type IV pilus minor pilin ComGD Machinery gene
  DQM67_RS09465 (NCTC12479_01833) comYC 1852574..1852891 (-) 318 WP_005591535.1 competence type IV pilus major pilin ComGC Machinery gene
  DQM67_RS09470 (NCTC12479_01834) comYB 1852888..1853904 (-) 1017 WP_255209852.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQM67_RS09475 (NCTC12479_01835) comYA 1853852..1854793 (-) 942 WP_005591533.1 competence type IV pilus ATPase ComGA Machinery gene
  DQM67_RS09480 (NCTC12479_01836) - 1854879..1855250 (-) 372 WP_005591532.1 DUF1033 family protein -
  DQM67_RS09485 (NCTC12479_01837) - 1855384..1856652 (-) 1269 WP_005591531.1 CapA family protein -
  DQM67_RS09495 (NCTC12479_01838) comW 1856896..1857123 (-) 228 WP_005592089.1 sigma(X)-activator ComW -
  DQM67_RS09500 (NCTC12479_01839) - 1857694..1858800 (-) 1107 WP_005591529.1 glycosyltransferase family 4 protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35842.01 Da        Isoelectric Point: 6.3924

>NTDB_id=1139538 DQM67_RS09475 WP_005591533.1 1853852..1854793(-) (comYA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
MVQKIAKEMIQLARQEAAQDVYLIPKSTCYELYMRVGDERRFIKTYDFDLLSSVISHFKFVSGMNVGEKRRSQLGSCDYD
CGDVTVSLRLSTVGDYRGYESLVIRLLHDEERELRFWFGNLPDLRKKVNSRGLYLFSGPVGSGKTTLMHQLAQMRFGQQQ
VMSIEDPVEIKQENMLQLQLNETIGMTYDSLIKLSLRHRPDLLIIGEIRDQETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEDELRMVLQGVCYQRLIGGGGVIDFVNQDYQKHEASLWNQQIDQLFADGHITDDQRQAEKIIYA

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1139538 DQM67_RS09475 WP_005591533.1 1853852..1854793(-) (comYA) [Streptococcus cristatus ATCC 51100 strain NCTC 12479]
ATGGTTCAAAAAATTGCAAAGGAAATGATTCAATTGGCCAGGCAGGAAGCAGCTCAAGATGTCTATCTGATTCCCAAGAG
CACCTGCTATGAGCTTTATATGCGGGTGGGTGATGAGCGGCGCTTCATTAAGACCTATGATTTTGATTTATTATCGTCAG
TCATCAGCCATTTTAAGTTTGTCTCGGGGATGAATGTCGGGGAGAAGAGGCGTAGTCAGCTAGGTTCCTGCGATTATGAT
TGTGGGGATGTAACGGTCTCGCTTCGTCTGTCGACCGTCGGGGATTACCGTGGCTATGAGAGTCTTGTGATTCGGCTCTT
ACACGATGAGGAGCGTGAGCTGCGTTTCTGGTTTGGCAATCTGCCTGATCTTCGTAAAAAAGTCAATTCTCGCGGCCTTT
ATCTCTTTTCAGGGCCAGTTGGCAGTGGAAAGACGACGCTGATGCACCAGCTGGCTCAGATGAGATTTGGGCAACAACAG
GTCATGTCTATCGAAGACCCTGTGGAAATCAAGCAGGAAAACATGCTCCAGCTTCAGCTGAATGAAACTATCGGGATGAC
CTATGACAGCCTCATCAAGCTGTCTCTGCGCCATCGGCCAGATCTCTTGATTATCGGGGAAATCCGAGACCAAGAAACGG
CTCGTGCGGTGGTAAGGGCTAGTTTGACAGGAGCCACGGTCTTTTCAACCATCCATGCTAAGAGCATTCGCGGAGTGTAT
GAGCGCCTGCTAGAGCTGGGTGTCAGTGAAGACGAGCTGCGTATGGTACTACAGGGCGTTTGTTACCAGCGTTTAATCGG
GGGAGGAGGTGTGATCGACTTTGTCAACCAAGACTATCAAAAGCATGAAGCCAGTCTCTGGAACCAGCAGATTGACCAGC
TTTTTGCAGATGGACATATCACAGATGATCAAAGGCAGGCGGAAAAAATTATCTACGCCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus gordonii str. Challis substr. CH1

78.71

99.042

0.78
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

74.121

100

0.741
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

73.163

100

0.732
  comGA/cglA/cilD Streptococcus pneumoniae D39

73.163

100

0.732
  comGA/cglA/cilD Streptococcus pneumoniae R6

73.163

100

0.732
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

73.163

100

0.732
  comYA Streptococcus mutans UA159

67.308

99.681

0.671
  comYA Streptococcus mutans UA140

67.308

99.681

0.671
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

63.871

99.042

0.633
  comGA Lactococcus lactis subsp. cremoris KW2

54.808

99.681

0.546
  comGA Latilactobacillus sakei subsp. sakei 23K

40.794

88.498

0.361

Multiple sequence alignment