Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYC   Type   Machinery gene
Locus tag   DQL25_RS00620 Genome accession   NZ_LS483330
Coordinates   97945..98271 (+) Length   108 a.a.
NCBI ID   WP_032465607.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain NCTC8328     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 92945..103271
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL25_RS00605 (NCTC8328_00121) - 95577..95942 (+) 366 WP_002986560.1 DUF1033 family protein -
  DQL25_RS00610 (NCTC8328_00122) comYA 96035..96973 (+) 939 WP_023612548.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL25_RS00615 (NCTC8328_00123) comYB 96909..97943 (+) 1035 WP_011054115.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL25_RS00620 (NCTC8328_00124) comYC 97945..98271 (+) 327 WP_032465607.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL25_RS00625 (NCTC8328_00125) comGD 98246..98674 (+) 429 WP_002986548.1 competence type IV pilus minor pilin ComGD -
  DQL25_RS00630 (NCTC8328_00126) comGE 98631..98915 (+) 285 WP_002987779.1 competence type IV pilus minor pilin ComGE -
  DQL25_RS00635 (NCTC8328_00127) comYF 98908..99342 (+) 435 WP_111703092.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL25_RS00640 (NCTC8328_00128) comGG 99326..99652 (+) 327 WP_002992739.1 competence type IV pilus minor pilin ComGG -
  DQL25_RS00645 (NCTC8328_00129) comYH 99750..100703 (+) 954 WP_002987790.1 class I SAM-dependent methyltransferase Machinery gene
  DQL25_RS00650 (NCTC8328_00130) - 100762..101958 (+) 1197 WP_023612537.1 acetate kinase -
  DQL25_RS00655 - 102145..102453 (+) 309 WP_111703093.1 hypothetical protein -

Sequence

Protein


Download         Length: 108 a.a.        Molecular weight: 12375.38 Da        Isoelectric Point: 10.0732

>NTDB_id=1136833 DQL25_RS00620 WP_032465607.1 97945..98271(+) (comYC) [Streptococcus pyogenes strain NCTC8328]
MINQWNNLRHKKLKGFTLLEMLLVILVISVLMLLFVPNLSKQKDRVTETGNAAVVKLVENQAELYELSQGSKPSLSQLKA
DGSITEKQEKAYQDYYNKHKNEKARLSN

Nucleotide


Download         Length: 327 bp        

>NTDB_id=1136833 DQL25_RS00620 WP_032465607.1 97945..98271(+) (comYC) [Streptococcus pyogenes strain NCTC8328]
ATGATTAATCAATGGAACAACTTACGACACAAGAAGCTAAAAGGATTTACTCTTCTAGAAATGTTATTGGTGATTCTTGT
CATCAGTGTTTTGATGCTATTATTTGTGCCTAATTTAAGCAAGCAAAAAGACAGGGTTACAGAAACAGGTAATGCCGCTG
TTGTTAAATTAGTGGAGAATCAAGCAGAACTATATGAATTATCTCAAGGCTCAAAACCAAGTTTGAGCCAGTTAAAGGCA
GATGGTAGTATCACTGAGAAACAAGAAAAAGCTTATCAAGACTATTATAACAAACATAAAAATGAAAAAGCCCGTCTTAG
CAATTAA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(12-34)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYC Streptococcus gordonii str. Challis substr. CH1

56.19

97.222

0.546
  comGC/cglC Streptococcus mitis SK321

61.957

85.185

0.528
  comGC Lactococcus lactis subsp. cremoris KW2

55.882

94.444

0.528
  comGC/cglC Streptococcus mitis NCTC 12261

60.87

85.185

0.519
  comGC/cglC Streptococcus pneumoniae TIGR4

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae Rx1

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae D39

59.783

85.185

0.509
  comGC/cglC Streptococcus pneumoniae R6

59.783

85.185

0.509
  comYC Streptococcus mutans UA140

55.208

88.889

0.491
  comYC Streptococcus mutans UA159

55.208

88.889

0.491
  comYC Streptococcus suis isolate S10

59.259

75

0.444

Multiple sequence alignment