Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA   Type   Machinery gene
Locus tag   DQL47_RS00750 Genome accession   NZ_LS483328
Coordinates   129560..130498 (+) Length   312 a.a.
NCBI ID   WP_111689764.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain NCTC12090     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 124560..135498
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  DQL47_RS00725 (NCTC12090_00146) - 124720..125766 (+) 1047 WP_172454096.1 acyltransferase family protein -
  DQL47_RS00730 (NCTC12090_00147) - 125827..126192 (+) 366 WP_012514777.1 DUF1033 family protein -
  DQL47_RS00735 - 126474..126665 (+) 192 Protein_113 lactococcin 972 family bacteriocin -
  DQL47_RS00740 (NCTC12090_00148) - 126730..128733 (+) 2004 WP_111689762.1 DUF1430 domain-containing protein -
  DQL47_RS00745 (NCTC12090_00149) - 128735..129403 (+) 669 WP_111689763.1 ATP-binding cassette domain-containing protein -
  DQL47_RS00750 (NCTC12090_00150) comGA/cglA 129560..130498 (+) 939 WP_111689764.1 competence type IV pilus ATPase ComGA Machinery gene
  DQL47_RS00755 (NCTC12090_00151) comYB 130431..131465 (+) 1035 WP_228274515.1 competence type IV pilus assembly protein ComGB Machinery gene
  DQL47_RS00760 (NCTC12090_00152) comGC/cglC 131466..131789 (+) 324 WP_111689766.1 competence type IV pilus major pilin ComGC Machinery gene
  DQL47_RS00765 (NCTC12090_00153) comGD 131767..132192 (+) 426 WP_111689767.1 competence type IV pilus minor pilin ComGD -
  DQL47_RS00770 comGE 132197..132439 (+) 243 WP_207622334.1 competence type IV pilus minor pilin ComGE -
  DQL47_RS00775 (NCTC12090_00154) comYF 132426..132860 (+) 435 WP_012677237.1 competence type IV pilus minor pilin ComGF Machinery gene
  DQL47_RS00780 (NCTC12090_00155) comGG 132838..133200 (+) 363 WP_037580629.1 competence type IV pilus minor pilin ComGG -
  DQL47_RS00785 (NCTC12090_00156) comYH 133262..134215 (+) 954 WP_021320264.1 class I SAM-dependent methyltransferase Machinery gene
  DQL47_RS00790 (NCTC12090_00157) - 134275..135474 (+) 1200 WP_021320265.1 acetate kinase -

Sequence

Protein


Download         Length: 312 a.a.        Molecular weight: 35427.63 Da        Isoelectric Point: 6.8990

>NTDB_id=1136718 DQL47_RS00750 WP_111689764.1 129560..130498(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
MVQELAKRLIRQAEELQAQDIYILPRGASYELLMRIGDDRRLIDVCESDRMANLISHFKFVAGMNVGEKRRCQLGACDYD
LDDTKVSLRLSAVGDYQGQESLVIRLLYHHQRQLRYWFDGLERVTSAIGARGLYLFSGPVGSGKTTLMYQLVSDYCKELQ
VISIEDPVEIKNDQLLQLQVNDSIGMTYDNLIKLSLRHRPDVLIIGEIRDTQTARAVIRASLTGAMVFSTVHAKSISGVY
ARLLELGISRAELDNSLAMVTYQRFISGGALIDCAQKEFEHHQANRWNQQIDQLLAEGHLNTRQARLEKIIQ

Nucleotide


Download         Length: 939 bp        

>NTDB_id=1136718 DQL47_RS00750 WP_111689764.1 129560..130498(+) (comGA/cglA) [Streptococcus equi subsp. zooepidemicus strain NCTC12090]
ATGGTTCAAGAATTAGCCAAGAGGCTTATCAGGCAGGCCGAAGAATTGCAGGCTCAGGATATTTATATACTGCCAAGAGG
GGCAAGCTATGAGCTTTTGATGAGGATAGGTGATGACAGGAGGCTAATAGATGTTTGTGAAAGTGATCGGATGGCTAATC
TTATTAGTCACTTTAAGTTCGTTGCAGGAATGAATGTGGGAGAAAAAAGACGCTGTCAGCTCGGTGCTTGTGACTACGAC
CTTGATGACACTAAGGTGTCTCTACGATTATCAGCTGTGGGTGATTATCAGGGACAGGAGAGCTTGGTTATTCGTCTCTT
GTATCATCATCAACGCCAGCTCAGGTATTGGTTTGATGGTTTAGAGCGAGTCACATCAGCTATTGGAGCTAGAGGCCTTT
ACCTCTTTTCTGGACCGGTTGGATCAGGTAAGACAACCCTGATGTATCAGCTAGTCTCTGACTATTGCAAGGAGCTTCAG
GTGATCAGTATTGAGGATCCTGTGGAAATTAAAAATGATCAGCTCCTGCAATTACAGGTTAACGACAGCATTGGCATGAC
ATACGATAATCTGATTAAGCTTTCCTTGCGTCATCGTCCAGATGTGTTGATTATCGGAGAAATCAGAGATACACAGACTG
CTAGAGCGGTTATTAGGGCTAGCCTGACAGGAGCAATGGTCTTTTCAACCGTCCATGCAAAGAGTATTTCAGGTGTTTAC
GCTAGGCTGTTAGAATTAGGCATTTCTAGGGCAGAATTGGATAATAGTCTAGCAATGGTTACTTACCAGCGATTTATTAG
TGGAGGTGCTTTAATTGATTGTGCACAAAAGGAATTTGAACATCATCAAGCCAACCGGTGGAATCAGCAGATTGATCAGC
TTCTTGCAGAGGGACATCTCAATACCAGGCAGGCAAGGCTTGAAAAAATTATCCAGTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(10-265)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.065

99.359

0.676
  comYA Streptococcus mutans UA140

63.987

99.679

0.638
  comYA Streptococcus mutans UA159

63.987

99.679

0.638
  comYA Streptococcus gordonii str. Challis substr. CH1

61.935

99.359

0.615
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

61.613

99.359

0.612
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae D39

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae R6

61.29

99.359

0.609
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

61.29

99.359

0.609
  comGA Lactococcus lactis subsp. cremoris KW2

52.733

99.679

0.526
  comGA Latilactobacillus sakei subsp. sakei 23K

39.931

92.308

0.369

Multiple sequence alignment