Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGA/cglA/cilD   Type   Machinery gene
Locus tag   FJH52_RS09835 Genome accession   NZ_LR595848
Coordinates   1942646..1943587 (-) Length   313 a.a.
NCBI ID   WP_000249550.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 4559 isolate 4559     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1937646..1948587
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FJH52_RS09795 comYH 1938139..1939092 (-) 954 WP_000345084.1 class I SAM-dependent methyltransferase Machinery gene
  FJH52_RS09800 - 1939153..1939740 (-) 588 Protein_1927 class I SAM-dependent methyltransferase -
  FJH52_RS09805 comGG/cglG 1939877..1940290 (-) 414 WP_000265617.1 competence type IV pilus minor pilin ComGG Machinery gene
  FJH52_RS09810 comGF/cglF 1940268..1940729 (-) 462 WP_000250529.1 competence type IV pilus minor pilin ComGF Machinery gene
  FJH52_RS09815 comGE/cglE 1940692..1940994 (-) 303 WP_000413382.1 competence type IV pilus minor pilin ComGE Machinery gene
  FJH52_RS09820 comGD/cglD 1940957..1941361 (-) 405 WP_000588002.1 competence type IV pilus minor pilin ComGD Machinery gene
  FJH52_RS09825 comGC/cglC 1941354..1941680 (-) 327 WP_000738623.1 comG operon protein ComGC Machinery gene
  FJH52_RS09830 comGB/cglB 1941682..1942698 (-) 1017 WP_077141332.1 competence type IV pilus assembly protein ComGB Machinery gene
  FJH52_RS09835 comGA/cglA/cilD 1942646..1943587 (-) 942 WP_000249550.1 competence type IV pilus ATPase ComGA Machinery gene
  FJH52_RS09840 - 1943663..1944028 (-) 366 WP_000286415.1 DUF1033 family protein -
  FJH52_RS09845 - 1944179..1945237 (-) 1059 WP_000649468.1 zinc-dependent alcohol dehydrogenase family protein -
  FJH52_RS09850 nagA 1945400..1946551 (-) 1152 WP_001134457.1 N-acetylglucosamine-6-phosphate deacetylase -
  FJH52_RS09855 - 1946704..1948521 (-) 1818 WP_001220850.1 acyltransferase family protein -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35516.43 Da        Isoelectric Point: 6.0083

>NTDB_id=1128362 FJH52_RS09835 WP_000249550.1 1942646..1943587(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 4559 isolate 4559]
MVQEIAQEIIRSARKKGAQDIYFVPKLDAYELHMRVGDERCKIGSYDFEKFAAVISHFKFVAGMNVGEKRRSQLGSCDYA
YDQKIASLRLSTVGDYRGHESLVIRLLHDEEQDLHFWFQDIEELGKQYRQRGLYLFAGPVGSGKTTLMHELSKSLFKGQQ
VMSIEDPVEIKQDDMLQLQLNEAIGLTYENLIKLSLRHRPDLLIIGEIRDSETARAVVRASLTGATVFSTIHAKSIRGVY
ERLLELGVSEEELAVVLQGVCYQRLIGGGGIVDFASRDYQEHQAAKWNEQIDQLLKDGHITSLQAETEKISYS

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1128362 FJH52_RS09835 WP_000249550.1 1942646..1943587(-) (comGA/cglA/cilD) [Streptococcus pneumoniae strain 4559 isolate 4559]
ATGGTTCAAGAAATTGCACAAGAAATCATTCGTTCGGCTCGGAAAAAAGGGGCGCAAGACATTTATTTTGTCCCTAAGTT
AGATGCCTATGAGCTTCATATGAGGGTAGGAGACGAGCGCTGTAAAATTGGTAGCTATGATTTTGAAAAGTTTGCAGCCG
TTATCAGTCACTTTAAGTTTGTGGCGGGTATGAATGTGGGAGAAAAAAGACGTAGTCAACTGGGTTCCTGTGATTATGCC
TATGACCAGAAGATAGCGTCTCTACGTTTATCTACTGTAGGCGATTATCGGGGGCATGAGAGTTTGGTTATCCGTTTGTT
GCACGATGAGGAGCAGGACTTGCATTTTTGGTTTCAGGATATTGAAGAATTAGGCAAGCAGTACAGGCAACGGGGACTCT
ATCTTTTTGCTGGTCCGGTTGGGAGTGGTAAGACGACCTTGATGCATGAATTGTCCAAGTCACTCTTTAAAGGACAGCAA
GTTATGTCCATCGAAGATCCTGTCGAAATCAAGCAGGACGACATGCTTCAGTTGCAGTTGAACGAAGCAATCGGCCTAAC
CTATGAAAATCTAATCAAACTTTCCTTGCGTCATCGACCAGATCTCTTGATTATCGGAGAAATTCGTGACAGCGAGACGG
CGCGTGCAGTGGTCAGAGCTAGTTTGACAGGTGCGACAGTCTTTTCAACCATTCACGCCAAAAGTATCCGAGGTGTTTAT
GAGCGTCTGCTGGAGTTGGGTGTGAGTGAAGAAGAATTGGCAGTTGTTCTGCAAGGAGTCTGCTACCAGAGATTAATCGG
GGGAGGAGGAATCGTTGACTTTGCAAGCAGAGATTATCAAGAACACCAAGCAGCCAAGTGGAATGAGCAAATTGACCAGC
TTCTTAAAGATGGACATATCACAAGTCTTCAGGCTGAGACGGAAAAAATTAGCTACAGCTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(9-266)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

99.361

100

0.994
  comGA/cglA/cilD Streptococcus pneumoniae D39

99.361

100

0.994
  comGA/cglA/cilD Streptococcus pneumoniae R6

99.361

100

0.994
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

99.361

100

0.994
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

96.486

100

0.965
  comYA Streptococcus gordonii str. Challis substr. CH1

78.387

99.042

0.776
  comYA Streptococcus mutans UA159

66.238

99.361

0.658
  comYA Streptococcus mutans UA140

66.238

99.361

0.658
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

62.903

99.042

0.623
  comGA Lactococcus lactis subsp. cremoris KW2

55.128

99.681

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

41.912

86.901

0.364

Multiple sequence alignment