Detailed information    

insolico Bioinformatically predicted

Overview

Name   ssbA   Type   Machinery gene
Locus tag   FGL18_RS09515 Genome accession   NZ_LR594046
Coordinates   1969073..1969465 (-) Length   130 a.a.
NCBI ID   WP_071127078.1    Uniprot ID   A0AAE4Q4B3
Organism   Streptococcus dysgalactiae strain NCTC6403     
Function   ssDNA binding (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1943447..1981610 1969073..1969465 within 0


Gene organization within MGE regions


Location: 1943447..1981610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL18_RS09355 (NCTC6403_01920) - 1943447..1944067 (-) 621 WP_012767582.1 hypothetical protein -
  FGL18_RS09360 (NCTC6403_01921) - 1944152..1944856 (-) 705 WP_138126613.1 exotoxin beta-grasp domain-containing protein -
  FGL18_RS09365 (NCTC6403_01922) - 1945222..1945626 (-) 405 WP_071127058.1 type II toxin-antitoxin system HicB family antitoxin -
  FGL18_RS09370 (NCTC6403_01923) - 1945686..1945871 (-) 186 WP_024376845.1 type II toxin-antitoxin system HicA family toxin -
  FGL18_RS09375 (NCTC6403_01924) - 1946081..1947286 (-) 1206 WP_172601457.1 N-acetylmuramoyl-L-alanine amidase -
  FGL18_RS09380 (NCTC6403_01925) - 1947288..1947623 (-) 336 WP_138126617.1 phage holin -
  FGL18_RS09385 (NCTC6403_01926) - 1947616..1948083 (-) 468 WP_003058491.1 phage holin family protein -
  FGL18_RS09390 (NCTC6403_01927) - 1948091..1948252 (-) 162 WP_172601458.1 hypothetical protein -
  FGL18_RS09395 (NCTC6403_01928) - 1948284..1948712 (-) 429 WP_138126621.1 DUF1366 domain-containing protein -
  FGL18_RS09400 (NCTC6403_01929) - 1948763..1950649 (-) 1887 WP_138126623.1 DUF859 family phage minor structural protein -
  FGL18_RS11025 (NCTC6403_01930) - 1950661..1953027 (-) 2367 Protein_1788 phage tail spike protein -
  FGL18_RS09410 (NCTC6403_01931) - 1953123..1953800 (-) 678 WP_071127064.1 phage tail domain-containing protein -
  FGL18_RS09415 (NCTC6403_01932) - 1953800..1957207 (-) 3408 WP_138126627.1 phage tail tape measure protein -
  FGL18_RS09420 (NCTC6403_01933) - 1957475..1957846 (-) 372 WP_071127066.1 hypothetical protein -
  FGL18_RS09425 (NCTC6403_01934) - 1957867..1958454 (-) 588 WP_003057267.1 hypothetical protein -
  FGL18_RS09430 (NCTC6403_01935) - 1958465..1958887 (-) 423 WP_002986168.1 hypothetical protein -
  FGL18_RS09435 (NCTC6403_01936) - 1958896..1959267 (-) 372 WP_002986170.1 hypothetical protein -
  FGL18_RS09440 (NCTC6403_01937) - 1959239..1959616 (-) 378 WP_003057300.1 hypothetical protein -
  FGL18_RS09445 (NCTC6403_01938) - 1959618..1959911 (-) 294 WP_138126629.1 phage gp6-like head-tail connector protein -
  FGL18_RS09450 (NCTC6403_01939) - 1959931..1960218 (-) 288 WP_071127068.1 hypothetical protein -
  FGL18_RS09455 (NCTC6403_01940) - 1960233..1961426 (-) 1194 WP_138126631.1 phage major capsid protein -
  FGL18_RS09460 (NCTC6403_01941) - 1961464..1962180 (-) 717 WP_138126633.1 head maturation protease, ClpP-related -
  FGL18_RS09465 (NCTC6403_01942) - 1962184..1963419 (-) 1236 WP_138126635.1 phage portal protein -
  FGL18_RS09470 (NCTC6403_01943) - 1963619..1965277 (-) 1659 WP_002986185.1 terminase TerL endonuclease subunit -
  FGL18_RS09475 (NCTC6403_01944) - 1965258..1965605 (-) 348 WP_002986187.1 hypothetical protein -
  FGL18_RS09480 (NCTC6403_01945) - 1965728..1966057 (-) 330 WP_071127073.1 HNH endonuclease -
  FGL18_RS09485 (NCTC6403_01946) - 1966054..1966347 (-) 294 WP_002986191.1 hypothetical protein -
  FGL18_RS09490 (NCTC6403_01947) - 1966519..1967082 (-) 564 WP_071127093.1 site-specific integrase -
  FGL18_RS09495 (NCTC6403_01948) - 1967177..1967596 (-) 420 WP_071127074.1 DUF1492 domain-containing protein -
  FGL18_RS09500 (NCTC6403_01949) - 1967620..1967820 (-) 201 WP_050317758.1 hypothetical protein -
  FGL18_RS10735 (NCTC6403_01950) - 1967789..1967938 (-) 150 WP_172601459.1 hypothetical protein -
  FGL18_RS10740 (NCTC6403_01951) - 1967941..1968114 (-) 174 WP_172601460.1 hypothetical protein -
  FGL18_RS09505 (NCTC6403_01952) - 1968111..1968440 (-) 330 WP_071127075.1 helix-turn-helix transcriptional regulator -
  FGL18_RS09510 (NCTC6403_01953) - 1968437..1968958 (-) 522 WP_071127076.1 hypothetical protein -
  FGL18_RS09515 (NCTC6403_01954) ssbA 1969073..1969465 (-) 393 WP_071127078.1 single-stranded DNA-binding protein Machinery gene
  FGL18_RS10745 (NCTC6403_01955) - 1969455..1969619 (-) 165 WP_172601461.1 hypothetical protein -
  FGL18_RS09520 (NCTC6403_01956) - 1969619..1969924 (-) 306 WP_138126637.1 DUF1372 family protein -
  FGL18_RS09525 (NCTC6403_01957) - 1969921..1970412 (-) 492 WP_138126639.1 MazG-like family protein -
  FGL18_RS09530 (NCTC6403_01958) - 1970414..1970653 (-) 240 WP_138126641.1 hypothetical protein -
  FGL18_RS09535 (NCTC6403_01959) dcm 1970650..1971963 (-) 1314 WP_138126643.1 DNA (cytosine-5-)-methyltransferase -
  FGL18_RS09540 (NCTC6403_01960) - 1971963..1972775 (-) 813 WP_138126645.1 ATP-binding protein -
  FGL18_RS09545 (NCTC6403_01961) - 1972775..1973536 (-) 762 WP_138126647.1 conserved phage C-terminal domain-containing protein -
  FGL18_RS09550 (NCTC6403_01962) - 1973529..1974116 (-) 588 WP_138126649.1 hypothetical protein -
  FGL18_RS09555 (NCTC6403_01963) dnaB 1974103..1975449 (-) 1347 WP_138126651.1 replicative DNA helicase -
  FGL18_RS09560 (NCTC6403_01965) - 1975643..1975903 (-) 261 WP_138126653.1 hypothetical protein -
  FGL18_RS09565 (NCTC6403_01966) - 1975968..1976705 (-) 738 WP_138126655.1 ORF6C domain-containing protein -
  FGL18_RS10970 (NCTC6403_01967) - 1976702..1976836 (-) 135 WP_264164507.1 hypothetical protein -
  FGL18_RS09570 (NCTC6403_01968) - 1976910..1977125 (-) 216 WP_002986282.1 hypothetical protein -
  FGL18_RS09575 (NCTC6403_01969) - 1977436..1977786 (+) 351 WP_032467305.1 helix-turn-helix transcriptional regulator -
  FGL18_RS09580 (NCTC6403_01970) - 1977796..1978176 (+) 381 WP_002986288.1 ImmA/IrrE family metallo-endopeptidase -
  FGL18_RS09585 (NCTC6403_01971) - 1978188..1978721 (+) 534 WP_136286795.1 hypothetical protein -
  FGL18_RS10795 (NCTC6403_01972) - 1978848..1979990 (+) 1143 WP_197733577.1 site-specific integrase -
  FGL18_RS09600 (NCTC6403_01974) - 1980390..1981610 (+) 1221 WP_138126657.1 transglutaminase domain-containing protein -

Sequence

Protein


Download         Length: 130 a.a.        Molecular weight: 14882.73 Da        Isoelectric Point: 5.8648

>NTDB_id=1127821 FGL18_RS09515 WP_071127078.1 1969073..1969465(-) (ssbA) [Streptococcus dysgalactiae strain NCTC6403]
MINNVVLIGRLTKDVELRYTPSQVACAQFTLAVNRNFKNQDGQKEADFINCVMWRQAAENLTNWTKKGHLIAITGRIQTR
NYENQNGQRIYVTEVVAESFQILEKRDNTANTNSLADTMPDYGQEPDLPF

Nucleotide


Download         Length: 393 bp        

>NTDB_id=1127821 FGL18_RS09515 WP_071127078.1 1969073..1969465(-) (ssbA) [Streptococcus dysgalactiae strain NCTC6403]
ATGATAAATAATGTTGTCCTGATTGGCCGCTTAACCAAAGATGTTGAGCTACGCTATACACCAAGTCAAGTAGCTTGCGC
ACAGTTTACTTTAGCAGTTAATCGTAATTTTAAAAATCAAGATGGGCAAAAAGAAGCTGATTTTATTAATTGTGTAATGT
GGCGACAAGCTGCTGAAAATTTAACAAATTGGACGAAAAAGGGACATCTGATTGCGATAACAGGACGCATTCAGACCCGT
AACTATGAGAATCAGAATGGTCAACGTATTTACGTGACAGAAGTGGTTGCCGAAAGTTTTCAAATTTTAGAGAAGCGTGA
TAATACAGCTAATACTAATAGCTTGGCAGATACCATGCCAGACTATGGACAGGAACCAGATTTACCATTTTAG

Domains

Predicted by InterproScan.

Single-strand binding protein family (SSB)

(2-102)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ssbA Bacillus subtilis subsp. subtilis str. 168

66.355

82.308

0.546
  ssb Latilactobacillus sakei subsp. sakei 23K

63.303

83.846

0.531
  ssbB Streptococcus sobrinus strain NIDR 6715-7

46.97

100

0.477
  ssbA Streptococcus mutans UA159

44.444

100

0.462
  ssbB/cilA Streptococcus pneumoniae TIGR4

44.697

100

0.454
  ssbB/cilA Streptococcus pneumoniae Rx1

43.939

100

0.446
  ssbB/cilA Streptococcus pneumoniae R6

43.939

100

0.446
  ssbB/cilA Streptococcus mitis SK321

43.939

100

0.446
  ssbB/cilA Streptococcus mitis NCTC 12261

43.939

100

0.446
  ssbB/cilA Streptococcus pneumoniae D39

43.939

100

0.446
  ssbB Bacillus subtilis subsp. subtilis str. 168

51.887

81.538

0.423
  ssbB Lactococcus lactis subsp. cremoris KW2

41.86

99.231

0.415

Multiple sequence alignment