Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYA   Type   Machinery gene
Locus tag   FGL06_RS00625 Genome accession   NZ_LR594042
Coordinates   96253..97194 (+) Length   313 a.a.
NCBI ID   WP_027968018.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8133     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 91253..102194
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS00615 (NCTC8133_00122) rpoC 92010..95648 (+) 3639 WP_024344490.1 DNA-directed RNA polymerase subunit beta' -
  FGL06_RS00620 (NCTC8133_00123) - 95816..96184 (+) 369 WP_021141429.1 DUF1033 family protein -
  FGL06_RS00625 (NCTC8133_00124) comYA 96253..97194 (+) 942 WP_027968018.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL06_RS00630 (NCTC8133_00125) comYB 97118..98161 (+) 1044 WP_164554342.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL06_RS00635 (NCTC8133_00126) comYC 98161..98463 (+) 303 WP_021141433.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL06_RS00640 (NCTC8133_00127) comGD 98438..98878 (+) 441 WP_126437530.1 competence type IV pilus minor pilin ComGD -
  FGL06_RS00645 (NCTC8133_00128) comGE 98832..99125 (+) 294 WP_039697664.1 competence type IV pilus minor pilin ComGE -
  FGL06_RS00650 (NCTC8133_00129) comYF 99109..99546 (+) 438 WP_126437531.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL06_RS00655 (NCTC8133_00130) comGG 99533..99868 (+) 336 WP_003067902.1 competence type IV pilus minor pilin ComGG -
  FGL06_RS00660 (NCTC8133_00131) comYH 99922..100878 (+) 957 WP_024344497.1 class I SAM-dependent methyltransferase Machinery gene
  FGL06_RS00665 (NCTC8133_00132) - 100932..102128 (+) 1197 WP_138083561.1 acetate kinase -

Sequence

Protein


Download         Length: 313 a.a.        Molecular weight: 35736.86 Da        Isoelectric Point: 5.7732

>NTDB_id=1127546 FGL06_RS00625 WP_027968018.1 96253..97194(+) (comYA) [Streptococcus equinus strain NCTC8133]
MIQEKAKQLIRDAVEKNAQDIYIIPKAENYEIYQRIGEKRQFIQEVATDEMTSLISHFKFVAGMNVGEKRRSQLGSCDYA
FADDEEISLRLSSVGDYRGRESLVIRLLYSGRHDLQYWFDGMRNILEAIDSRGLYLFSGPVGSGKTTLMYQLVREKFPGK
QVITIEDPVEIKQDNMLQLQLNDEIGMTYDNLIKLSLRHRPDILIIGEIRDSETARAVIRASLTGVLVFSTIHAKSIPGV
YARLLELGVSRQELENSLRAIVYQRLIGGGGVVDFAKRDFEQYPPTRWNEQIDSLARDGHISFEEAKIEKIAL

Nucleotide


Download         Length: 942 bp        

>NTDB_id=1127546 FGL06_RS00625 WP_027968018.1 96253..97194(+) (comYA) [Streptococcus equinus strain NCTC8133]
ATGATTCAGGAAAAAGCAAAGCAGCTCATTAGAGATGCGGTTGAAAAGAATGCTCAGGATATCTATATTATTCCAAAGGC
AGAAAACTATGAGATTTATCAACGAATTGGTGAGAAACGTCAGTTTATTCAAGAAGTTGCTACTGATGAAATGACAAGCT
TGATTAGTCACTTTAAATTTGTAGCTGGGATGAATGTTGGTGAAAAGCGTCGTAGTCAGCTTGGTTCTTGTGACTATGCT
TTTGCAGATGATGAGGAGATTTCACTGCGCTTGTCTAGTGTGGGTGATTATCGTGGGCGTGAAAGTCTGGTCATTAGGCT
CCTTTATTCAGGTCGTCATGATTTGCAGTATTGGTTTGATGGAATGAGAAACATTTTAGAGGCTATTGACAGTAGGGGAC
TTTACCTTTTTTCCGGTCCGGTAGGGAGTGGAAAAACCACTCTCATGTACCAATTAGTTCGTGAAAAATTTCCTGGAAAG
CAGGTGATTACGATTGAAGACCCTGTTGAGATTAAGCAGGACAATATGTTGCAATTGCAGTTGAATGATGAAATCGGGAT
GACTTATGATAATCTTATCAAGCTCTCGCTTCGTCATAGACCTGATATTTTGATTATTGGTGAGATTCGTGATAGTGAGA
CAGCGCGTGCGGTTATTAGAGCTAGTCTGACAGGAGTCCTTGTTTTTTCAACCATTCATGCGAAAAGTATTCCCGGTGTT
TATGCTAGGTTATTAGAATTGGGTGTTAGTAGGCAGGAACTTGAAAATAGCTTGCGCGCTATTGTTTATCAACGATTAAT
TGGTGGTGGAGGTGTAGTTGATTTTGCCAAAAGAGATTTTGAGCAGTATCCCCCAACAAGGTGGAATGAGCAAATTGATA
GCCTTGCTCGAGACGGACATATCAGTTTTGAAGAGGCAAAAATCGAAAAAATTGCCCTTTAA

Domains

Predicted by InterproScan.

Type II/IV secretion system protein (T2SSE)

(8-267)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYA Streptococcus mutans UA159

71.061

99.361

0.706
  comYA Streptococcus mutans UA140

70.74

99.361

0.703
  comGA/cglA Streptococcus sobrinus strain NIDR 6715-7

68.71

99.042

0.681
  comYA Streptococcus gordonii str. Challis substr. CH1

65.916

99.361

0.655
  comGA/cglA/cilD Streptococcus pneumoniae Rx1

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae D39

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae R6

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus pneumoniae TIGR4

64.103

99.681

0.639
  comGA/cglA/cilD Streptococcus mitis NCTC 12261

64.103

99.681

0.639
  comGA Lactococcus lactis subsp. cremoris KW2

54.952

100

0.55
  comGA Latilactobacillus sakei subsp. sakei 23K

42.701

87.54

0.374

Multiple sequence alignment