Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYB   Type   Machinery gene
Locus tag   FGL06_RS00630 Genome accession   NZ_LR594042
Coordinates   97118..98161 (+) Length   347 a.a.
NCBI ID   WP_164554342.1    Uniprot ID   -
Organism   Streptococcus equinus strain NCTC8133     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 92118..103161
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL06_RS00620 (NCTC8133_00123) - 95816..96184 (+) 369 WP_021141429.1 DUF1033 family protein -
  FGL06_RS00625 (NCTC8133_00124) comYA 96253..97194 (+) 942 WP_027968018.1 competence type IV pilus ATPase ComGA Machinery gene
  FGL06_RS00630 (NCTC8133_00125) comYB 97118..98161 (+) 1044 WP_164554342.1 competence type IV pilus assembly protein ComGB Machinery gene
  FGL06_RS00635 (NCTC8133_00126) comYC 98161..98463 (+) 303 WP_021141433.1 competence type IV pilus major pilin ComGC Machinery gene
  FGL06_RS00640 (NCTC8133_00127) comGD 98438..98878 (+) 441 WP_126437530.1 competence type IV pilus minor pilin ComGD -
  FGL06_RS00645 (NCTC8133_00128) comGE 98832..99125 (+) 294 WP_039697664.1 competence type IV pilus minor pilin ComGE -
  FGL06_RS00650 (NCTC8133_00129) comYF 99109..99546 (+) 438 WP_126437531.1 competence type IV pilus minor pilin ComGF Machinery gene
  FGL06_RS00655 (NCTC8133_00130) comGG 99533..99868 (+) 336 WP_003067902.1 competence type IV pilus minor pilin ComGG -
  FGL06_RS00660 (NCTC8133_00131) comYH 99922..100878 (+) 957 WP_024344497.1 class I SAM-dependent methyltransferase Machinery gene
  FGL06_RS00665 (NCTC8133_00132) - 100932..102128 (+) 1197 WP_138083561.1 acetate kinase -
  FGL06_RS00670 (NCTC8133_00133) - 102286..102483 (+) 198 WP_021141442.1 helix-turn-helix transcriptional regulator -
  FGL06_RS00675 (NCTC8133_00134) - 102538..102990 (+) 453 WP_126437532.1 ABC transporter permease -

Sequence

Protein


Download         Length: 347 a.a.        Molecular weight: 39721.11 Da        Isoelectric Point: 9.7102

>NTDB_id=1127547 FGL06_RS00630 WP_164554342.1 97118..98161(+) (comYB) [Streptococcus equinus strain NCTC8133]
MSKLIALLETDISVLKRQKSKKLPFKKQQKVIQLFNNLFNSGFTLTEIVSFLRRSQLLQESYVDSMQESLLSGATLADMM
ARLGFSDTIVTQIALADVHGNCQQSLVKIDRYLASMSVVRKKLIEVATYPLILLSFLILIMLGLKNYLLPQLESQNFATQ
IIAHFPMIFLGSFVLLGLAVVLGFFYARRLSPIHLFSQISRLPIIGRFIRLYLTAYYAREWGNLIGQGIDLMEIVALMQH
QKSRLFQEIGKDMQQALLSGQSFHQKVLDYPFFLRELSLMIEYGEVKSKLGRELDIYAEETWQTFFSQLTQATQLIQPLV
FVFVALIIVLIYVAMLLPMYQNMGGNF

Nucleotide


Download         Length: 1044 bp        

>NTDB_id=1127547 FGL06_RS00630 WP_164554342.1 97118..98161(+) (comYB) [Streptococcus equinus strain NCTC8133]
ATGAGCAAATTGATAGCCTTGCTCGAGACGGACATATCAGTTTTGAAGAGGCAAAAATCGAAAAAATTGCCCTTTAAGAA
ACAACAGAAGGTCATTCAATTATTTAATAATTTATTTAACAGTGGCTTTACTTTAACTGAAATAGTGTCCTTTTTGAGAC
GAAGTCAGTTATTGCAGGAATCTTATGTGGATAGCATGCAGGAGTCCTTGCTGAGTGGCGCAACTTTAGCAGATATGATG
GCAAGGTTAGGCTTTTCAGACACGATTGTGACTCAGATTGCTTTGGCTGATGTTCATGGAAATTGTCAGCAAAGTCTTGT
AAAAATAGATCGTTATTTGGCTAGCATGTCTGTTGTGCGAAAGAAGTTGATTGAAGTAGCGACCTATCCTTTGATTTTAT
TAAGTTTTTTGATTTTGATAATGCTTGGCTTAAAAAATTATTTATTGCCGCAACTTGAAAGTCAAAATTTTGCTACTCAG
ATTATTGCCCATTTTCCAATGATTTTCTTGGGGAGCTTTGTACTTTTAGGACTAGCAGTTGTTTTGGGATTTTTCTATGC
TAGGCGTTTATCCCCAATCCATCTTTTTAGCCAGATTAGTCGCTTGCCGATAATAGGGCGATTCATTCGTCTTTATCTAA
CAGCTTATTATGCGCGTGAGTGGGGAAATCTTATTGGGCAGGGAATTGATTTGATGGAAATTGTAGCCTTGATGCAACAT
CAAAAGTCGCGTCTTTTTCAAGAGATTGGTAAGGATATGCAGCAAGCTCTTTTGTCTGGTCAATCATTTCACCAAAAGGT
CTTAGATTATCCCTTCTTTTTGAGGGAACTGAGCCTGATGATTGAGTACGGAGAAGTTAAGTCAAAACTTGGTCGGGAGC
TTGATATCTATGCTGAGGAAACATGGCAGACTTTCTTTAGCCAATTAACTCAGGCAACACAGCTGATTCAACCGCTAGTT
TTTGTCTTTGTTGCTTTAATTATTGTTTTAATCTACGTGGCAATGCTTTTGCCAATGTATCAAAATATGGGAGGAAATTT
TTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(218-338)

Type II secretion system (T2SS), protein F (T2SSF)

(33-150)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYB Streptococcus mutans UA140

63.158

98.559

0.622
  comYB Streptococcus mutans UA159

63.158

98.559

0.622
  comYB Streptococcus gordonii str. Challis substr. CH1

58.309

98.847

0.576
  comGB/cglB Streptococcus mitis NCTC 12261

58.16

97.118

0.565
  comGB/cglB Streptococcus mitis SK321

57.567

97.118

0.559
  comGB/cglB Streptococcus pneumoniae Rx1

57.27

97.118

0.556
  comGB/cglB Streptococcus pneumoniae D39

57.27

97.118

0.556
  comGB/cglB Streptococcus pneumoniae R6

57.27

97.118

0.556
  comGB/cglB Streptococcus pneumoniae TIGR4

57.27

97.118

0.556
  comGB Lactococcus lactis subsp. cremoris KW2

50.296

97.406

0.49

Multiple sequence alignment