Detailed information NTG1127389

Bioinformatically predicted

Overview

• Name: comYC
• Type: Machinery gene
• Locus tag: FGK97_RS01020
• Genome accession: NZ_LR594037
• Coordinates: 192619..192936 (+)
• Length: 105 a.a.
• NCBI ID: WP_003028473.1
• Uniprot ID: A0A0P0N5S2
• Organism: Streptococcus anginosus strain NCTC11064
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 187619..197936

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK97_RS00990 (NCTC11064_00194)	-	187742..188272 (+)	531	WP_003032280.1	FUSC family protein	-
FGK97_RS00995 (NCTC11064_00195)	-	188349..188708 (+)	360	WP_003028467.1	MerR family transcriptional regulator	-
FGK97_RS01000 (NCTC11064_00196)	glnA	188747..190093 (+)	1347	WP_106079126.1	type I glutamate--ammonia ligase	-
FGK97_RS01005 (NCTC11064_00197)	-	190282..190647 (+)	366	WP_003027003.1	DUF1033 family protein	-
FGK97_RS01010 (NCTC11064_00198)	comYA	190717..191658 (+)	942	WP_003027001.1	competence type IV pilus ATPase ComGA	Machinery gene
FGK97_RS01015 (NCTC11064_00199)	comYB	191600..192622 (+)	1023	WP_041783985.1	competence type IV pilus assembly protein ComGB	Machinery gene
FGK97_RS01020 (NCTC11064_00200)	comYC	192619..192936 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
FGK97_RS01025 (NCTC11064_00201)	comYD	192896..193324 (+)	429	WP_171004445.1	competence type IV pilus minor pilin ComGD	Machinery gene
FGK97_RS01030 (NCTC11064_00202)	comGE/cglE	193296..193589 (+)	294	WP_021001233.1	competence type IV pilus minor pilin ComGE	Machinery gene
FGK97_RS01035 (NCTC11064_00203)	comGF/cglF	193573..194010 (+)	438	WP_041783987.1	competence type IV pilus minor pilin ComGF	Machinery gene
FGK97_RS01040 (NCTC11064_00204)	comGG	193991..194317 (+)	327	WP_021001234.1	competence type IV pilus minor pilin ComGG	-
FGK97_RS01045 (NCTC11064_00205)	comYH	194389..195342 (+)	954	WP_138099333.1	class I SAM-dependent methyltransferase	Machinery gene
FGK97_RS01050 (NCTC11064_00206)	-	195389..196588 (+)	1200	WP_021001236.1	acetate kinase	-

Sequence

Protein

• Length: 105 a.a.
• Molecular weight: 11622.72 Da
• Isoelectric Point: 10.1006

>NTDB_id=1127389 FGK97_RS01020 WP_003028473.1 192619..192936(+) (comYC) [Streptococcus anginosus strain NCTC11064]
MKKLKSLKVKGFTLVEMLVVLLIISVLMLLFVPNLTKQKEAVTEKGNAAVVKVVESQAELFEVNHTNEKATLSKLVNEGT
ITDKQAASYKAYYAKHTKEARSVAD

Nucleotide

• Length: 318 bp

>NTDB_id=1127389 FGK97_RS01020 WP_003028473.1 192619..192936(+) (comYC) [Streptococcus anginosus strain NCTC11064]
ATGAAAAAATTAAAAAGTTTGAAGGTTAAAGGTTTTACTTTAGTAGAAATGTTAGTCGTACTTCTTATCATCAGTGTTTT
GATGCTCTTATTTGTACCGAATTTGACCAAGCAAAAAGAAGCTGTAACGGAAAAAGGAAATGCAGCGGTGGTAAAAGTTG
TGGAAAGCCAAGCGGAGCTGTTTGAGGTCAATCACACCAATGAAAAAGCGACACTCTCAAAATTAGTCAACGAAGGCACG
ATTACAGACAAGCAGGCAGCATCTTATAAGGCTTACTATGCGAAACATACAAAAGAAGCTCGTTCTGTTGCAGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (8-30)

3D structure

• AlphaFold DB: A0A0P0N5S2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYC	Streptococcus gordonii str. Challis substr. CH1	73.333	100	0.733
comYC	Streptococcus mutans UA159	66.667	100	0.667
comYC	Streptococcus mutans UA140	66.667	100	0.667
comGC/cglC	Streptococcus mitis NCTC 12261	68.627	97.143	0.667
comGC/cglC	Streptococcus mitis SK321	68.627	97.143	0.667
comGC/cglC	Streptococcus pneumoniae R6	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae D39	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae Rx1	66.667	97.143	0.648
comGC/cglC	Streptococcus pneumoniae TIGR4	66.667	97.143	0.648
comYC	Streptococcus suis isolate S10	66.292	84.762	0.562
comGC	Lactococcus lactis subsp. cremoris KW2	54.808	99.048	0.543