Detailed information NTG1127392

Bioinformatically predicted

Overview

• Name: comGF/cglF
• Type: Machinery gene
• Locus tag: FGK97_RS01035
• Genome accession: NZ_LR594037
• Coordinates: 193573..194010 (+)
• Length: 145 a.a.
• NCBI ID: WP_041783987.1
• Uniprot ID: A0AAP6EPH2
• Organism: Streptococcus anginosus strain NCTC11064
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 188573..199010

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGK97_RS01000 (NCTC11064_00196)	glnA	188747..190093 (+)	1347	WP_106079126.1	type I glutamate--ammonia ligase	-
FGK97_RS01005 (NCTC11064_00197)	-	190282..190647 (+)	366	WP_003027003.1	DUF1033 family protein	-
FGK97_RS01010 (NCTC11064_00198)	comYA	190717..191658 (+)	942	WP_003027001.1	competence type IV pilus ATPase ComGA	Machinery gene
FGK97_RS01015 (NCTC11064_00199)	comYB	191600..192622 (+)	1023	WP_041783985.1	competence type IV pilus assembly protein ComGB	Machinery gene
FGK97_RS01020 (NCTC11064_00200)	comYC	192619..192936 (+)	318	WP_003028473.1	competence type IV pilus major pilin ComGC	Machinery gene
FGK97_RS01025 (NCTC11064_00201)	comYD	192896..193324 (+)	429	WP_171004445.1	competence type IV pilus minor pilin ComGD	Machinery gene
FGK97_RS01030 (NCTC11064_00202)	comGE/cglE	193296..193589 (+)	294	WP_021001233.1	competence type IV pilus minor pilin ComGE	Machinery gene
FGK97_RS01035 (NCTC11064_00203)	comGF/cglF	193573..194010 (+)	438	WP_041783987.1	competence type IV pilus minor pilin ComGF	Machinery gene
FGK97_RS01040 (NCTC11064_00204)	comGG	193991..194317 (+)	327	WP_021001234.1	competence type IV pilus minor pilin ComGG	-
FGK97_RS01045 (NCTC11064_00205)	comYH	194389..195342 (+)	954	WP_138099333.1	class I SAM-dependent methyltransferase	Machinery gene
FGK97_RS01050 (NCTC11064_00206)	-	195389..196588 (+)	1200	WP_021001236.1	acetate kinase	-
FGK97_RS01055 (NCTC11064_00207)	glmS	196940..198754 (+)	1815	WP_138099541.1	glutamine--fructose-6-phosphate transaminase (isomerizing)	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16769.29 Da
• Isoelectric Point: 10.0941

>NTDB_id=1127392 FGK97_RS01035 WP_041783987.1 193573..194010(+) (comGF/cglF) [Streptococcus anginosus strain NCTC11064]
MFKANKVKAFTLLEALIALFVISGSVLLFQSMTRLLASEVQARQHSEQREWLLFADQLEAELARSSFEKVENNRLYMKQD
GKVIAFGKSSGQDFRKTNANGKGYQPMVYDVKKAEISQKNELIHVRLTFRRGLEREFVYRVETES

Nucleotide

• Length: 438 bp

>NTDB_id=1127392 FGK97_RS01035 WP_041783987.1 193573..194010(+) (comGF/cglF) [Streptococcus anginosus strain NCTC11064]
GTGTTCAAGGCAAATAAAGTGAAAGCTTTTACCCTTTTAGAGGCTCTGATTGCCCTCTTTGTCATTAGTGGAAGTGTGTT
GCTGTTTCAATCTATGACGCGCCTTCTAGCTTCTGAAGTCCAAGCTCGTCAACACAGTGAACAACGAGAATGGCTTTTGT
TTGCAGATCAACTAGAAGCAGAGTTGGCTCGTTCTTCATTTGAAAAGGTGGAGAATAATCGTTTATATATGAAACAGGAC
GGCAAGGTGATTGCATTTGGAAAGTCAAGTGGACAGGATTTCAGAAAAACCAATGCGAATGGGAAAGGTTACCAGCCGAT
GGTTTATGATGTAAAAAAAGCAGAAATCTCACAGAAAAATGAGCTGATTCATGTTAGACTGACGTTTAGGCGAGGATTGG
AAAGGGAGTTTGTCTATCGTGTGGAAACAGAAAGTTAA

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (38-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGF/cglF	Streptococcus pneumoniae R6	66.901	97.931	0.655
comGF/cglF	Streptococcus pneumoniae TIGR4	66.901	97.931	0.655
comGF/cglF	Streptococcus pneumoniae Rx1	66.901	97.931	0.655
comGF/cglF	Streptococcus pneumoniae D39	66.901	97.931	0.655
comGF/cglF	Streptococcus mitis NCTC 12261	67.143	96.552	0.648
comGF/cglF	Streptococcus mitis SK321	67.143	96.552	0.648
comYF	Streptococcus mutans UA159	45.185	93.103	0.421
comYF	Streptococcus mutans UA140	45.185	93.103	0.421
comGF	Lactococcus lactis subsp. cremoris KW2	42.222	93.103	0.393