Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   EL133_RS02930 Genome accession   NZ_LR134323
Coordinates   571383..571853 (+) Length   156 a.a.
NCBI ID   WP_006739527.1    Uniprot ID   G5KDJ0
Organism   Streptococcus urinalis strain NCTC13766     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 566383..576853
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EL133_RS02905 (NCTC13766_00592) - 568100..568354 (-) 255 WP_006738513.1 GIY-YIG nuclease family protein -
  EL133_RS02910 - 568356..568583 (-) 228 WP_006740416.1 hypothetical protein -
  EL133_RS02915 (NCTC13766_00593) - 568558..569337 (-) 780 WP_006739967.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  EL133_RS02920 (NCTC13766_00594) - 569416..570339 (-) 924 WP_006739084.1 polysaccharide deacetylase family protein -
  EL133_RS02925 (NCTC13766_00595) - 570466..571206 (+) 741 WP_006738486.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  EL133_RS02930 (NCTC13766_00597) comEA 571383..571853 (+) 471 WP_006739527.1 helix-hairpin-helix domain-containing protein Machinery gene
  EL133_RS11550 (NCTC13766_00598) - 572074..572814 (+) 741 WP_040832718.1 ComEC/Rec2 family competence protein -
  EL133_RS11795 (NCTC13766_00599) - 572705..573304 (+) 600 WP_406874637.1 ComEC/Rec2 family competence protein -
  EL133_RS02940 (NCTC13766_00600) comEC 573364..573663 (+) 300 WP_006738752.1 MBL fold metallo-hydrolase Machinery gene
  EL133_RS02945 (NCTC13766_00601) comEC/celB 573677..574081 (+) 405 WP_006740411.1 ComEC/Rec2 family competence protein Machinery gene
  EL133_RS02950 (NCTC13766_00602) - 574204..574632 (+) 429 WP_006740037.1 PTS sugar transporter subunit IIA -
  EL133_RS02955 (NCTC13766_00603) - 574643..575134 (+) 492 WP_006739599.1 PTS sugar transporter subunit IIB -
  EL133_RS02960 (NCTC13766_00604) - 575151..575963 (+) 813 WP_006739400.1 PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC -
  EL133_RS02965 (NCTC13766_00605) - 575960..576787 (+) 828 WP_006739879.1 PTS system mannose/fructose/sorbose family transporter subunit IID -

Sequence

Protein


Download         Length: 156 a.a.        Molecular weight: 17340.40 Da        Isoelectric Point: 4.7830

>NTDB_id=1121525 EL133_RS02930 WP_006739527.1 571383..571853(+) (comEA) [Streptococcus urinalis strain NCTC13766]
MDQQKQQTYQFEEKTAAPIEEKPIKEEKANTAESQTITVDLKGAVKNEGVYQIEKGNRLFDLIQKAGGLTPEADKKSINL
ASKLADEQLIYVAKVGEEVVSNVTNNHQESSSSTTIVNINKANLEELQTITGIGQKKAQEIINYREKNGLFKSIED

Nucleotide


Download         Length: 471 bp        

>NTDB_id=1121525 EL133_RS02930 WP_006739527.1 571383..571853(+) (comEA) [Streptococcus urinalis strain NCTC13766]
GTGGATCAACAAAAACAACAAACCTATCAATTTGAAGAAAAAACTGCTGCTCCGATAGAAGAAAAACCTATAAAAGAAGA
AAAGGCAAATACAGCAGAGAGTCAAACAATAACCGTTGATTTAAAAGGTGCGGTAAAAAACGAGGGGGTATATCAAATAG
AGAAAGGTAACAGGCTATTTGATCTTATCCAAAAAGCTGGAGGCTTGACACCTGAAGCTGACAAGAAATCAATTAATTTA
GCATCAAAGTTAGCTGATGAACAACTTATTTATGTGGCAAAAGTTGGTGAAGAAGTGGTTAGTAATGTTACCAATAATCA
TCAAGAGTCAAGCTCTAGTACAACAATTGTTAATATCAATAAAGCAAATTTAGAAGAATTACAGACTATTACTGGTATAG
GACAGAAAAAAGCACAAGAGATTATCAATTATAGAGAAAAGAATGGACTATTTAAATCAATTGAAGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(115-156)

SLBB domain (SLBB)

(39-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G5KDJ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Lactococcus lactis subsp. cremoris KW2

59.843

81.41

0.487
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

53.6

80.128

0.429
  comEA/celA/cilE Streptococcus pneumoniae Rx1

53.6

80.128

0.429
  comEA/celA/cilE Streptococcus pneumoniae R6

53.6

80.128

0.429
  comEA/celA/cilE Streptococcus pneumoniae D39

53.6

80.128

0.429
  comEA Bacillus subtilis subsp. subtilis str. 168

44.898

94.231

0.423
  comEA/celA/cilE Streptococcus mitis NCTC 12261

52

80.128

0.417
  comEA/celA/cilE Streptococcus mitis SK321

52.893

77.564

0.41
  comEA Streptococcus thermophilus LMD-9

46.457

81.41

0.378
  comEA Latilactobacillus sakei subsp. sakei 23K

40.426

90.385

0.365

Multiple sequence alignment