Detailed information NTG1121526

Bioinformatically predicted

Overview

• Name: comEC
• Type: Machinery gene
• Locus tag: EL133_RS02940
• Genome accession: NZ_LR134323
• Coordinates: 573364..573663 (+)
• Length: 99 a.a.
• NCBI ID: WP_006738752.1
• Uniprot ID: G5KDJ3
• Organism: Streptococcus urinalis strain NCTC13766
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 568364..578663

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EL133_RS02915 (NCTC13766_00593)	-	568558..569337 (-)	780	WP_006739967.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
EL133_RS02920 (NCTC13766_00594)	-	569416..570339 (-)	924	WP_006739084.1	polysaccharide deacetylase family protein	-
EL133_RS02925 (NCTC13766_00595)	-	570466..571206 (+)	741	WP_006738486.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
EL133_RS02930 (NCTC13766_00597)	comEA	571383..571853 (+)	471	WP_006739527.1	helix-hairpin-helix domain-containing protein	Machinery gene
EL133_RS11550 (NCTC13766_00598)	-	572074..572814 (+)	741	WP_040832718.1	ComEC/Rec2 family competence protein	-
EL133_RS11795 (NCTC13766_00599)	-	572705..573304 (+)	600	WP_406874637.1	ComEC/Rec2 family competence protein	-
EL133_RS02940 (NCTC13766_00600)	comEC	573364..573663 (+)	300	WP_006738752.1	MBL fold metallo-hydrolase	Machinery gene
EL133_RS02945 (NCTC13766_00601)	comEC/celB	573677..574081 (+)	405	WP_006740411.1	ComEC/Rec2 family competence protein	Machinery gene
EL133_RS02950 (NCTC13766_00602)	-	574204..574632 (+)	429	WP_006740037.1	PTS sugar transporter subunit IIA	-
EL133_RS02955 (NCTC13766_00603)	-	574643..575134 (+)	492	WP_006739599.1	PTS sugar transporter subunit IIB	-
EL133_RS02960 (NCTC13766_00604)	-	575151..575963 (+)	813	WP_006739400.1	PTS mannose/fructose/sorbose/N-acetylgalactosamine transporter subunit IIC	-
EL133_RS02965 (NCTC13766_00605)	-	575960..576787 (+)	828	WP_006739879.1	PTS system mannose/fructose/sorbose family transporter subunit IID	-
EL133_RS02970 (NCTC13766_00606)	-	576873..578510 (+)	1638	WP_006738925.1	sensor histidine kinase	-

Sequence

Protein

• Length: 99 a.a.
• Molecular weight: 11131.80 Da
• Isoelectric Point: 10.1934

>NTDB_id=1121526 EL133_RS02940 WP_006738752.1 573364..573663(+) (comEC) [Streptococcus urinalis strain NCTC13766]
MVDIGQGDSILLREKFGKVILIDLGGIPGFKQKENWRQRTIKSNAEQTLIPFLKSRGISTIDQVILTHTDTDHAGDLEVV
HHHIKIKKSSSTFSFFKSS

Nucleotide

• Length: 300 bp

>NTDB_id=1121526 EL133_RS02940 WP_006738752.1 573364..573663(+) (comEC) [Streptococcus urinalis strain NCTC13766]
ATGGTTGATATTGGTCAAGGTGACAGTATTTTATTACGAGAAAAATTTGGGAAAGTCATTTTAATTGATTTAGGCGGTAT
CCCTGGGTTTAAACAGAAAGAAAACTGGCGACAAAGAACAATAAAATCAAACGCCGAACAGACTTTAATTCCGTTTTTGA
AAAGTCGTGGAATATCAACAATTGATCAAGTGATATTAACTCACACTGATACTGATCATGCAGGAGACTTAGAAGTGGTT
CATCATCATATTAAAATTAAAAAATCTAGTAGTACCTTTTCATTCTTTAAAAGTTCATGA

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (5-87)

3D structure

• AlphaFold DB: G5KDJ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC	Lactococcus lactis subsp. cremoris KW2	55.682	88.889	0.495
comEC/celB	Streptococcus mitis NCTC 12261	57.692	78.788	0.455
comEC/celB	Streptococcus mitis SK321	56.41	78.788	0.444
comEC/celB	Streptococcus pneumoniae TIGR4	55.128	78.788	0.434
comEC/celB	Streptococcus pneumoniae Rx1	53.846	78.788	0.424
comEC/celB	Streptococcus pneumoniae D39	53.846	78.788	0.424
comEC/celB	Streptococcus pneumoniae R6	53.846	78.788	0.424
comEC	Bacillus subtilis subsp. subtilis str. 168	43.956	91.919	0.404
comEC	Latilactobacillus sakei subsp. sakei 23K	40.449	89.899	0.364